1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE

Product Name: 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
CAS No.: 17082-61-0
Chemical Name: 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
Synonyms: 1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE;1,2-Bis((triMethylsilyl)oxy)cyclobut-1-ene;DK105;DK578;obutene;DKSI111;95+%(gc);oxy)cycL;Hexacosanoic acid ≥4-Aminomethylindole &ge
CBNumber: CB3400436
Molecular Formula: C10H22O2Si2
Formula Weight: 230.45
MOL File: 17082-61-0.mol

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1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Property

Boiling point:: 58-59 °C2 mm Hg(lit.)
Density: 0.897 g/mL at 25 °C(lit.)
refractive index: n20/D 1.435(lit.)
Flash point:: 142 °F
storage temp.: Inert atmosphere,2-8°C
solubility: sol hydrocarbons and ethers.
form: clear liquid
color: Colorless to Light yellow
Specific Gravity: 0.87
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
BRN: 1367530
InChI: InChI=1S/C10H22O2Si2/c1-13(2,3)11-9-7-8-10(9)12-14(4,5)6/h7-8H2,1-6H3
InChIKey: WOBRFSDEZREQAB-UHFFFAOYSA-N
SMILES: C1(O[Si](C)(C)C)CCC=1O[Si](C)(C)C
CAS DataBase Reference: 17082-61-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: 1993
WGK Germany: 3
F: 10-21
TSCA: No
HS Code: 2931.90.6000
Storage Class: 10 - Combustible liquids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 293830
Product name: 1,2-Bis(trimethylsiloxy)cyclobutene
Purity: ≥95%
Packaging: 5g
Price: $148
Updated: 2023/01/07

TCI Chemical

Product number: B1768
Product name: 1,2-Bis(trimethylsilyloxy)cyclobutene
Purity: >94.0%(GC)
Packaging: 1g
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: B1768
Product name: 1,2-Bis(trimethylsilyloxy)cyclobutene
Purity: >94.0%(GC)
Packaging: 5g
Price: $158
Updated: 2025/07/31

TRC

Product number: B535288
Product name: 1,2-Bis(trimethylsilyloxy)cyclobutene
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B535288
Product name: 1,2-Bis(trimethylsilyloxy)cyclobutene
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

1,2-Bis(trimethylsilyloxy)cyclobutene is a useful chemical reactant used in the preparation and biological activity of serine and threonine β-lactones as inhibitors of hepatitis A virus 3C cysteine proteinase.

Application

Used as a suitable reagent for annulation processes and 4-keto ester synthesis.

General Description

Photocycloaddition of 2-cyclohexenones to 1,2-bis(trimethyl-siloxy)cyclobutene has been studied. It undergoes Aldol condensation reaction with carbonyl compounds. It reacts with Br₂ to give cyclobutanedione.

Synthesis

1,2-Bis(trimethylsilyloxy)cyclobutene is prepared as a colorless liquid by acyloin condensation of Diethyl Succinate (dispersed Na in toluene or Et2O, reflux) using Chlorotrimethylsilane as trapping agent.

storage

Use in a fume hood; the compound is stable for years if stored in a tightly screw-capped bottle. Prolonged exposure to moist air leads to decomposition.

1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Suppliers

Americas 1 Belgium 1 China 113 Europe 1 France 1 Germany 2 India 2 Japan 1 Singapore 1 Switzerland 1 United Kingdom 6 United States 14 Global 144

nanjing huayan chemical corp.

Tel: 25-25-86661363 18951712139
Email: ruishi@hychemm.com
Country: China
ProdList: 64
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 11999
Advantage: 60

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@163.com
Country: China
ProdList: 283
Advantage: 58

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

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View Lastest Price from 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1,2-Bis(trimethylsiloxy)cyclobutene >=95% 17082-61-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE 17082-61-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100
Release date: 2019-06-28

17082-61-0, 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENERelated Search:

(N,N-DIMETHYLAMINO)DIMETHYLCHLOROSILANE (N,N-DIMETHYLAMINO)TRIETHYLSILANE N,N-Dimethyltrimethylsilylamine tert-Butyldimethylsilyl chloride 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Trimethyl(propoxy)silane ISOPROPENYLOXYTRIMETHYLSILANE VINYLOXYTRIMETHYLSILANE

1,2-Bis(triMethylsiloxy)cyclobutene >=95%

4-methoxy-2-vinylbenzenamine &ge

2-Chloro-1,3-thiazole &ge

2,6-diethylpyridine &ge

3-Bromo-5-ethyl-2-methylpyridine &ge

(4-Methyl-1,3-thiazol-2-yl)methanol &ge

Methyl 3-(3-bromophenyl)-3-oxopropanoate &ge

tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate &ge

Benzyl chloromethyl ether &ge

4-Aminomethylindole &ge

Phenoxyethyl chloroformate &ge

1-Boc-4-cyclopropylaminopiperidine &ge

2-Ethyl-4-methyl-1H-imidazole-1-propanenitrile &ge

2-Bromo-3-methylpyridine &ge

Hexacosanoic acid &ge

6-butylpyridin-2-amine &ge

5-Bromo-4-methylthiazole &ge

BIS(TRIMETHYLSILOXY)CYCLOBUTENE

1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE

1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE

1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE PURUM 95+ % (GC)

1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE, 9 5+%

1,2-Bis(trimethylsiloxy)cyclobutenepurum

95+%(gc)

BIS(TRIMETHYLSILOXY)CYCLOBUTENE ,95%

[1-Cyclobutene-1,2-diylbis(oxy)]bis[trimethylsilane]

1,2-Bis(trimethylsiloxy)-1-cyclobutene

triMethyl({1-[(triMethylsilyl)oxy]cyclobut-2-en-1-yl}oxy)silane

1,2-Bis((triMethylsilyl)oxy)cyclobut-1-ene

Ethylene glycol-monopentylether &ge

4-Hydroxymethylthiazole &ge

Pentachloronitrobenzene &ge

2-Chloro-1-N-isopropylimidazole &ge

2-Chloro-1N-ethyl-imidazole &ge

Diallyl pyrocarbonate &ge

(Tetrahydropyran-2-yl)methylamine &ge

Di-tert-butyl-N,N-diisopropylphosphoramidite &ge

Cis-3-(4-Tert-Butoxycarbonylaminocyclohexyl)Propionic Acid &ge

4-Phenylpyrrolidine-3-methylcarboxylate &ge

3-Chloro-5-methylpyridazine &ge

N-Methyl-4-hydroxymethylpiperidine &ge

4,5,6,7-Tetrahydrothieno[3,2-c]pyridine &ge

2-Bromo-5-fluoro-3-methylpyridine &ge

Ethyl 2-bromo-2-(4-fluorophenyl)acetate &ge

Ethyl 2-methylacetoacetate &ge

trimethyl({2-[(trimethylsilyl)oxy]cyclobut-1-en-1-yl}oxy)silane

1-Methyl-piperidine-4-carbonitrile &ge

1,2-Bis(trimethylsilyloxy)cyclobutene &gt

oxy)cycL

obutene

Cyclobutene, 1,2-bis[(trimethylsilyl)oxy]-

DK105

DK578

trimethyl-(2-trimethylsilyloxycyclobuten-1-yl)oxy-silane

DKSI111

1,2-Bis((trimethylsilyl)oxy)cyclobut-1-ene - [B3339]

17082-61-0

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