ChemicalBook > CAS DataBase List > 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE

1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE

Product Name
1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
CAS No.
17082-61-0
Chemical Name
1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
Synonyms
1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE;1,2-Bis((triMethylsilyl)oxy)cyclobut-1-ene;DK105;DK578;obutene;DKSI111;95+%(gc);oxy)cycL;Hexacosanoic acid ≥4-Aminomethylindole &ge
CBNumber
CB3400436
Molecular Formula
C10H22O2Si2
Formula Weight
230.45
MOL File
17082-61-0.mol
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1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Property

Boiling point:
58-59 °C2 mm Hg(lit.)
Density 
0.897 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.435(lit.)
Flash point:
142 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
sol hydrocarbons and ethers.
form 
clear liquid
color 
Colorless to Light yellow
Specific Gravity
0.87
Hydrolytic Sensitivity
7: reacts slowly with moisture/water
BRN 
1367530
InChI
InChI=1S/C10H22O2Si2/c1-13(2,3)11-9-7-8-10(9)12-14(4,5)6/h7-8H2,1-6H3
InChIKey
WOBRFSDEZREQAB-UHFFFAOYSA-N
SMILES
C1(O[Si](C)(C)C)CCC=1O[Si](C)(C)C
CAS DataBase Reference
17082-61-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
1993
WGK Germany 
3
10-21
TSCA 
No
HS Code 
2931.90.6000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
293830
Product name
1,2-Bis(trimethylsiloxy)cyclobutene
Purity
≥95%
Packaging
5g
Price
$148
Updated
2023/01/07
TCI Chemical
Product number
B1768
Product name
1,2-Bis(trimethylsilyloxy)cyclobutene
Purity
>94.0%(GC)
Packaging
1g
Price
$54
Updated
2025/07/31
TCI Chemical
Product number
B1768
Product name
1,2-Bis(trimethylsilyloxy)cyclobutene
Purity
>94.0%(GC)
Packaging
5g
Price
$158
Updated
2025/07/31
TRC
Product number
B535288
Product name
1,2-Bis(trimethylsilyloxy)cyclobutene
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
B535288
Product name
1,2-Bis(trimethylsilyloxy)cyclobutene
Packaging
100mg
Price
$45
Updated
2021/12/16
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1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

1,2-Bis(trimethylsilyloxy)cyclobutene is a useful chemical reactant used in the preparation and biological activity of serine and threonine β-lactones as inhibitors of hepatitis A virus 3C cysteine proteinase.

Application

Used as a suitable reagent for annulation processes and 4-keto ester synthesis.

General Description

Photocycloaddition of 2-cyclohexenones to 1,2-bis(trimethyl-siloxy)cyclobutene has been studied. It undergoes Aldol condensation reaction with carbonyl compounds. It reacts with Br2 to give cyclobutanedione.

Synthesis

1,2-Bis(trimethylsilyloxy)cyclobutene is prepared as a colorless liquid by acyloin condensation of Diethyl Succinate (dispersed Na in toluene or Et2O, reflux) using Chlorotrimethylsilane as trapping agent.

storage

Use in a fume hood; the compound is stable for years if stored in a tightly screw-capped bottle. Prolonged exposure to moist air leads to decomposition.

1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE Suppliers

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View Lastest Price from 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1,2-Bis(trimethylsiloxy)cyclobutene >=95% 17082-61-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE 17082-61-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100
Release date
2019-06-28

17082-61-0, 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENERelated Search:


  • 1,2-Bis(triMethylsiloxy)cyclobutene >=95%
  • 4-methoxy-2-vinylbenzenamine &ge
  • 2-Chloro-1,3-thiazole &ge
  • 2,6-diethylpyridine &ge
  • 3-Bromo-5-ethyl-2-methylpyridine &ge
  • (4-Methyl-1,3-thiazol-2-yl)methanol &ge
  • Methyl 3-(3-bromophenyl)-3-oxopropanoate &ge
  • tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate &ge
  • Benzyl chloromethyl ether &ge
  • 4-Aminomethylindole &ge
  • Phenoxyethyl chloroformate &ge
  • 1-Boc-4-cyclopropylaminopiperidine &ge
  • 2-Ethyl-4-methyl-1H-imidazole-1-propanenitrile &ge
  • 2-Bromo-3-methylpyridine &ge
  • Hexacosanoic acid &ge
  • 6-butylpyridin-2-amine &ge
  • 5-Bromo-4-methylthiazole &ge
  • BIS(TRIMETHYLSILOXY)CYCLOBUTENE
  • 1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE
  • 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
  • 1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE PURUM 95+ % (GC)
  • 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE, 9 5+%
  • 1,2-Bis(trimethylsiloxy)cyclobutenepurum
  • 95+%(gc)
  • BIS(TRIMETHYLSILOXY)CYCLOBUTENE ,95%
  • [1-Cyclobutene-1,2-diylbis(oxy)]bis[trimethylsilane]
  • 1,2-Bis(trimethylsiloxy)-1-cyclobutene
  • triMethyl({1-[(triMethylsilyl)oxy]cyclobut-2-en-1-yl}oxy)silane
  • 1,2-Bis((triMethylsilyl)oxy)cyclobut-1-ene
  • Ethylene glycol-monopentylether &ge
  • 4-Hydroxymethylthiazole &ge
  • Pentachloronitrobenzene &ge
  • 2-Chloro-1-N-isopropylimidazole &ge
  • 2-Chloro-1N-ethyl-imidazole &ge
  • Diallyl pyrocarbonate &ge
  • (Tetrahydropyran-2-yl)methylamine &ge
  • Di-tert-butyl-N,N-diisopropylphosphoramidite &ge
  • Cis-3-(4-Tert-Butoxycarbonylaminocyclohexyl)Propionic Acid &ge
  • 4-Phenylpyrrolidine-3-methylcarboxylate &ge
  • 3-Chloro-5-methylpyridazine &ge
  • N-Methyl-4-hydroxymethylpiperidine &ge
  • 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine &ge
  • 2-Bromo-5-fluoro-3-methylpyridine &ge
  • Ethyl 2-bromo-2-(4-fluorophenyl)acetate &ge
  • Ethyl 2-methylacetoacetate &ge
  • trimethyl({2-[(trimethylsilyl)oxy]cyclobut-1-en-1-yl}oxy)silane
  • 1-Methyl-piperidine-4-carbonitrile &ge
  • 1,2-Bis(trimethylsilyloxy)cyclobutene &gt
  • oxy)cycL
  • obutene
  • Cyclobutene, 1,2-bis[(trimethylsilyl)oxy]-
  • DK105
  • DK578
  • trimethyl-(2-trimethylsilyloxycyclobuten-1-yl)oxy-silane
  • DKSI111
  • 1,2-Bis((trimethylsilyl)oxy)cyclobut-1-ene - [B3339]
  • 17082-61-0
  • Building Blocks