2-AMINO-5-PHENYLPYRIDINE
- Product Name
- 2-AMINO-5-PHENYLPYRIDINE
- CAS No.
- 33421-40-8
- Chemical Name
- 2-AMINO-5-PHENYLPYRIDINE
- Synonyms
- PHE-P-1;AKOS BAR-1613;5-PHENYL-2-PYRIDINAMINE;5-Phenyl-2-aminopyridine;2-amino-5-phenyl-pyridin;2-AMINO-5-PHENYLPYRIDINE;2-pyridinaMine, 5-phenyl-;5-PHENYL-PYRIDIN-2-YLAMINE;2-Amino-5-phenylpyridine,97%;2-Amino-5-phenylpyridine >
- CBNumber
- CB3401529
- Molecular Formula
- C11H10N2
- Formula Weight
- 170.21
- MOL File
- 33421-40-8.mol
2-AMINO-5-PHENYLPYRIDINE Property
- Melting point:
- 132 °C
- Boiling point:
- 324℃
- Density
- 1.133
- refractive index
- 1.5200 (estimate)
- Flash point:
- 176℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 6.32±0.13(Predicted)
- color
- Off-White to Light Yellow
- CAS DataBase Reference
- 33421-40-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-36-22-40
- Safety Statements
- 26-36/37/39-36/37
- RTECS
- US2145000
- HS Code
- 29333990
- Toxicity
- mma-sat 100 mg/plate CPBTAL 26,611,78
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A1667
- Product name
- 2-Amino-5-phenylpyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $286
- Updated
- 2025/07/31
- Product number
- A1667
- Product name
- 2-Amino-5-phenylpyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 100mg
- Price
- $46
- Updated
- 2025/07/31
- Product number
- A626745
- Product name
- 2-Amino-5-phenylpyridine
- Packaging
- 2.5g
- Price
- $215
- Updated
- 2021/12/16
- Product number
- 3H30-1-KS
- Product name
- 2-Amino-5-phenylpyridine
- Purity
- 97%
- Packaging
- 5G
- Price
- $311
- Updated
- 2021/12/16
- Product number
- CS-W002820
- Product name
- 2-Amino-5-phenylpyridine
- Purity
- >97.0%
- Packaging
- 5g
- Price
- $71
- Updated
- 2021/12/16
2-AMINO-5-PHENYLPYRIDINE Chemical Properties,Usage,Production
Chemical Properties
Beige Crystalline Solid
Uses
A product from the pyrolysis of phenylalanine
Definition
ChEBI: 5-Phenyl-2-pyridinamine is a phenylpyridine.
Safety Profile
Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.
Synthesis
66600-05-3
33421-40-8
The general procedure for the synthesis of 2-amino-5-phenylpyridine from 2-chloro-5-phenylpyridine is as follows: 1. a solution was prepared by dissolving 2-chloro-5-phenylpyridine (4.0 g, 0.021 mol) in anhydrous ether (160 ml). 2. the above solution was slowly added dropwise to a solution of liquid ammonia (160 ml) containing sodium (3.39 g, 0.15 g atoms) and ferrous nitrate hexahydrate (0.095 g). 3. The resulting suspension was heated to reflux for 4 hours. 4. Upon completion of the reaction, ammonium chloride was added and the ammonia was allowed to evaporate naturally. 5. The residue is treated with a 5% aqueous sodium hydroxide solution (5 mL). 6. Filter the mixture to separate the solids from the liquid. 7. Extract the aqueous layer with ether (2 x 100 ml) and combine the ether layers. 8. Wash the combined ether layers with brine and dry with sodium sulfate. 9. The dried ether solution was concentrated to give the crude product. 10. the crude product was recrystallized with methylcyclohexane. 11. 11. The recrystallized product was ground with chloroform (100 ml). 12. The mixture was filtered and the filtrate was evaporated to give the final product 2-amino-5-phenylpyridine (1.3 g, 36% yield) with a melting point of 205 °C. Melting points of 133°-135° have been reported in the literature (Chem. Ber., 91, 247 (1958)).
References
[1] Patent: US4122274, 1978, A
2-AMINO-5-PHENYLPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-5-PHENYLPYRIDINE Suppliers
- Tel
- --
- Fax
- --
- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from 2-AMINO-5-PHENYLPYRIDINE manufacturers
- Product
- 2-AMINO-5-PHENYLPYRIDINE 33421-40-8
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-08-22
- Product
- 2-AMINO-5-PHENYLPYRIDINE 33421-40-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-26
- Product
- 2-AMINO-5-PHENYLPYRIDINE 33421-40-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-25