PERIODIC ACID Property

Melting point:

122 °C (lit.)

Boiling point:

140°C

Density 

d417 1.3875; d 1.42

vapor pressure 

7.6Pa at 25℃

RTECS 

NN1269700

Flash point:

140°C

storage temp. 

Store at +15°C to +25°C.

solubility 

soluble in Methanol, Water

form 

Solid

color 

White to slightly yellow

PH

1.2 (100g/l, H2O, 20℃)

Water Solubility 

Soluble in water and alcohols.

Sensitive 

Moisture & Light Sensitive

Merck 

14,7171

Stability:

Stable, but strong oxidizer. Contact with combustible material may cause fire. Hygroscopic. Incompatible with organic materials, strong reducing agents.

InChIKey

TWLXDPFBEPBAQB-UHFFFAOYSA-N

CAS DataBase Reference

10450-60-9(CAS DataBase Reference)

EPA Substance Registry System

Periodic acid (H5IO6) (10450-60-9)

Safety

Hazard Codes 

C,O

Risk Statements 

8-34

Safety Statements 

26-27-36/37/39-45-17-36

RIDADR 

UN 3264 8/PG 2

WGK Germany 

3

F 

3-8

TSCA 

Yes

HS Code 

2811 19 80

HazardClass 

5.1

PackingGroup 

II

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H271May cause fire or explosion; strong oxidiser

H314Causes severe skin burns and eye damage

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

PERIODIC ACID Chemical Properties,Usage,Production

Chemical Properties

PERIODIC ACID is colourless crystals

Physical properties

In dilute solution, periodic acid exists as H⁺ and IO4^-. When more concentrated, orthoperiodic acid, H5IO6, is formed. Note that this compound is essentially a dihydrate, HIO4·2H2O. This can be obtained as a crystalline solid. O-periodic acid can be dehydrated to metaperiodic acid, m-HIO4. Further heating gives di-iodine pentoxide (I2O5) and O2. The anhydride di-iodine heptoxide, i.e. I2O7, does not exist in nature but can be formed synthetically.

Uses

Periodic acid is used as a component for glycoprotein stains. It serves as a pharmaceutical and synthetic intermediate and is used in silk screen printing. It acts as an oxidizing agent especially the cleavage of 1,2 diols to prepare dialdehydes. It has selective oxidation powers which makes it an ideal reagent for the reclamation of silk screens in the printing industry. It finds application in life sciences for the analysis of intracellular polysaccharides like glycogen, starch and cellulose. Furthermore, it is used in the oxidation reactions converting sulfides into sulfones, catalyzed by chromium(VI) oxide and oxidation reactions converting alcohols to aldehydes and ketones.

Uses

In organic synthesis.

Uses

PERIODIC ACID is used as an oxidiser and in the determination of manganese.

Production Methods

A 100-g quantity of Ba3H4(IO6)2 is moistened with 75 ml H2O and treated with 200 ml of colourless nitric acid. The agitated mixture is heated to 60-70°C for an hour and is then cooled to 30-40°C. The precipitated Ba(NO3)2 is filtered off on a glass frit. The residue is washed free of periodate by stirring with concentrated nitric acid. The combined filtrate is evaporated at 60-70°C in an aspirator vacuum [if more Ba(NO3)s separates, it is filtered, and the evaporation continues] until H5IO6 begins to precipitate. After cooling, glistening crystals of periodic acid are formed. Since the solution tends to become supersaturated, it is often necessary to wait a long time. The crystals are filtered off and dried in a vacuum at 50°C. A second crystal crop may be obtained from the mother liquor by evaporation.

Definition

ChEBI: Orthoperiodic acid is an iodine oxoacid. It is a conjugate acid of an orthoperiodate(1-).

Reactions

Paraperiodic acid H5IO6, is obtained from sodium paraperiodate, formed by action of chlorine upon a NaOH solution containing I2. On vacuum drying, paraperiodic acid yields metaperiodic acid, HIO4, and dimesoperiodic acid, H4I2O9; which form heteropoly acids with a number of oxides and acids. The periodic acids and their salts are strong oxidizing agents both with inorganic and organic compounds.

General Description

Periodic acid (H₅IO₆) is an oxoacid of iodine. It is commonly used as an oxidizing agent in organic synthesis for the preparation of useful chemical intermediates. Periodic acid is also used in oxidative cleavage reactions.

Flammability and Explosibility

Not classified