5-IODOCYTOSINE

Product Name: 5-IODOCYTOSINE
CAS No.: 1122-44-7
Chemical Name: 5-IODOCYTOSINE
Synonyms: IODOCYTOSINE;5-IODOCYTOSINE;5-iodo-cytosin;5-iodocytomidine;Cytosine, 5-iodo-;5-Iodocytosine ,98%;5-IODOCYTOSINE USP/EP/BP;4-Amino-5-iodopyrimidin-2(1H);4-Amino-5-iodopyrimidin-2(1H)-one;4-Amino-5-iodo-2(1H)-pyrimidinone
CBNumber: CB9203633
Molecular Formula: C4H4IN3O
Formula Weight: 237
MOL File: 1122-44-7.mol

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5-IODOCYTOSINE Property

Density: 2.65±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: formic acid: 50mg/mL
pka: 7.58±0.10(Predicted)
form: powder
Appearance: Off-white to light yellow Solid
biological source: synthetic (organic)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 24/25
WGK Germany: 3
RTECS: HA6125000
F: 8-10-23
HS Code: 29335990
Toxicity: mouse,LDLo,intraperitoneal,50mg/kg (50mg/kg),Biochemical Pharmacology. Vol. 13, Pg. 1249, 1964.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I6875
Product name: 5-Iodocytosine
Packaging: 5g
Price: $441.5
Updated: 2025/07/31

Usbiological

Product number: 280296
Product name: 5-Iodocytosine
Packaging: 1g
Price: $545
Updated: 2021/12/16

TRC

Product number: A612778
Product name: 6-Amino-5-iodopyrimidin-2(1H)-one
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A612778
Product name: 6-Amino-5-iodopyrimidin-2(1H)-one
Packaging: 500mg
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 090392
Product name: 6-Amino-5-iodopyrimidin-2(1H)-one
Purity: 95+%
Packaging: 1g
Price: $105
Updated: 2021/12/16

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5-IODOCYTOSINE Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

6-Amino-5-iodopyrimidin-2(1H)-one is an iodinated nucleobase for peptide modified nucleic acids.

Synthesis

71-30-7

1122-44-7

A mixture of N-iodosuccinimide (18.562 g, 82.5 mmol) and 6-aminopyrimidin-2(1H)-one (8.333 g, 75 mmol) was dissolved in DMF (50 mL) under argon protection. The reaction vessel was covered with aluminum foil and sonicated for 30 min to fully dissolve the solids at the bottom. Subsequently, the reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the mixture was poured into water (150 mL) to quench the reaction. The resulting precipitate was collected by filtration, washed with water and dried in the presence of phosphorus pentoxide (P2O5) to afford 4-amino-5-iodopyrimidin-2(1H)-one as a light tan solid (17.703 g, 99% yield). The product could be used in the subsequent reaction without further purification.

References

[1] Patent: US7741294, 2010, B1. Location in patent: Page/Page column 17
[2] European Journal of Organic Chemistry, 2015, vol. 2015, # 32, p. 7160 - 7175
[3] Journal of Medicinal Chemistry, 1983, vol. 26, # 2, p. 152 - 156
[4] Tetrahedron, 2012, vol. 68, # 26, p. 5145 - 5151
[5] Journal of Heterocyclic Chemistry, 2015, vol. 52, # 5, p. 1382 - 1389

5-IODOCYTOSINE Preparation Products And Raw materials

Raw materials

Periodic acid Cytosine Carbon tetrachloride Iodine Acetic acid

Preparation Products

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5-IODOCYTOSINE Suppliers

Canada 1 China 89 Europe 2 Germany 1 India 4 Japan 1 Russia 1 Switzerland 1 United Kingdom 2 United States 15 Global 117

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
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Beijing HwrkChemical Technology Co., Ltd

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Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
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Shandong Xiya Chemical Co., Ltd

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Spectrum Chemical Manufacturing Corp.

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Hangzhou Sage Chemical Co., Ltd.

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Shanghai potentpharm CO.,Ltd

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shanghai aokchem co., ltd

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Shanghai Yolne Chemical Co., Ltd.

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Bide Pharmatech Ltd.

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Email: product02@bidepharm.com
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View Lastest Price from 5-IODOCYTOSINE manufacturers

Career Henan Chemical Co

Product: 5-IODOCYTOSINE 1122-44-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

1122-44-7, 5-IODOCYTOSINERelated Search:

6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE 5-Iodo-2'-deoxycytidine 5-IODOCYTOSINE Fiacitabine 1-BETA-D-RIBOFURANOSYL-5-IODOCYTOSINE,1-D-Ribofuranosyl-5-iodocytosine 2''-DEOXY-2''-FLUORO-5-IODOCYTIDINE 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE N4-(DIISOBUTYLAMINOMETHYLIDENE)-5-IODO-2'-O-METHYL-CYTIDINE (N4-BZ)-5-IODO-2'-DEOXYCYTIDINE 5-IODO-2'-O-METHYLCYTIDINE 5'-O-(DIMETHOXYTRITYL)-N4-DIMETHYLAMINOMETHYLIDENE-5-IODO-2'-DEOXYCYTIDINE N4-DIISOBUTYLAMINOMETHYLIDENE-5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-O-METHYLCYTIDINE 2,2'-anhydro-1-(3'-O-acetyl-beta-arabinofuranosyl)-5-iodocytosine 2'-DEOXYCYTIDINE, 5-[125I]IODO- 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5-[125I]IODO-,TETRAAMMONIUM SALT 5-IODOCYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT 5-IODO-2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, SODIUM SALT 5-IODO-2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT

5-iodo-cytosin

Cytosine, 5-iodo-

IODOCYTOSINE

5-IODOCYTOSINE

4-AMINO-2-HYDROXY-5-IODO-1 BETA-D-RIBOFURANOSYL PURIMIDINE

4-AMINO-2-HYDROXY-5-IODOPYRIMIDINE

4-Amino-5-iodo-2(1H)-pyrimidinone

4-Amino-5-iodopyrimidin-2(1H)-one

5-Iodocytosine ,98%

6-amino-5-iodo-1H-pyrimidin-2-one

6-azanyl-5-iodo-1H-pyrimidin-2-one

4-aMino-5-iodo-1,2-dihydropyriMidin-2-one

6-AMino-5-iodopyriMidin-2(1H)-one

2(1H)-PyriMidinone, 6-aMino-5-iodo-

4-amino-5-iodo-3H-pyrimidin-2-one

4-Amino-5-iodopyrimidin-2(1H)

4-Amino-5-iodo-1H-pyrimidin-2-one

5-IODOCYTOSINE USP/EP/BP

5-iodocytomidine

1122-44-7

C4H4IN3O

Biochemicals and Reagents

BioChemical

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides