5-Iodocytidine

Product Name: 5-Iodocytidine
CAS No.: 1147-23-5
Chemical Name: 5-Iodocytidine
Synonyms: 5-IC;5-I-Cr;iodocytidine;5-IODOCYTIDINE;5-Iodo-D-cytidine;Cytidine, 5-iodo-;5-IODOCYTIDINE,99+%;5-lodo-cytidine(5-I-Cr);5-Iodocytidine USP/EP/BP;1-D-Ribofuranosyl-5-iodocytosine
CBNumber: CB4422468
Molecular Formula: C9H12IN3O5
Formula Weight: 369.11
MOL File: 1147-23-5.mol

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5-Iodocytidine Property

Melting point:: >160°C (dec.)
Boiling point:: 565.5±60.0 °C(Predicted)
Density: 2.52±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka: 13.48±0.70(Predicted)
form: Crystalline or Powder
color: White to Off-white
Sensitive: Light Sensitive
Stability:: Light Sensitive
InChI: InChI=1S/C9H12IN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1
InChIKey: LQQGJDJXUSAEMZ-UAKXSSHOSA-N
SMILES: OC[C@H]1O[C@@H](N2C=C(I)C(N)=NC2=O)[C@H](O)[C@@H]1O

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Safety

Safety Statements: 24/25
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 296192
Product name: 5-Iodocytidine
Packaging: 1g
Price: $319
Updated: 2021/12/16

Usbiological

Product number: I8447-36
Product name: 5-Iodocytidine
Packaging: 10mg
Price: $355
Updated: 2021/12/16

Ark Pharm

Product number: P000311790
Product name: 5-Iodo-cytidine
Purity: 98%
Packaging: 250mg
Price: $25
Updated: 2021/12/16

Ark Pharm

Product number: P000311790
Product name: 5-Iodo-cytidine
Purity: 98%
Packaging: 1g
Price: $38
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NI04748
Product name: 5-Iodocytidine
Packaging: 1g
Price: $50
Updated: 2021/12/16

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5-Iodocytidine Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions

Synthesis

65-46-3

1147-23-5

Synthesis of 5-iodocytidine 191: Cytidine 190 (15.0 g, 61.7 mmol) was dissolved in a mixed solvent of 225 mL of acetic acid and 225 mL of carbon tetrachloride, and heated to 40 °C. Subsequently, iodine (9.6 g, 75.7 mmol) was added. A solution prepared from iodic acid (9.6 g, 54.6 mmol) dissolved in 25 mL of water was added slowly dropwise with stirring, and the time of dropwise addition was controlled within 10 minutes. The reaction mixture was stirred continuously at 40 °C for 6 h, followed by stirring at room temperature overnight. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was concentrated under reduced pressure. The crude product was purified by fast chromatography on silica gel columns, using a gradient elution of dichloromethane-methanol (15:1 to 10:1 to 5:1), resulting in 19.4 g (85.1% yield) of the target product 5-iodocytidine (191).

References

[1] Patent: WO2015/196130, 2015, A2. Location in patent: Page/Page column 634; 635
[2] Patent: WO2015/196128, 2015, A2. Location in patent: Page/Page column 642
[3] Patent: EP2918275, 2015, A1. Location in patent: Paragraph 2219; 2220
[4] Patent: EP2918275, 2016, B1. Location in patent: Paragraph 2219; 2220
[5] Journal of the American Chemical Society, 2015, vol. 137, # 1, p. 34 - 37

5-Iodocytidine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Iodocytidine Suppliers

Canada 2 China 116 Germany 1 India 4 United Kingdom 5 United States 15 Global 143

Shanghai Xuanheng Pharmaceutical Technology Co., LTD

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J & K SCIENTIFIC LTD.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Hongene Biotech Corporation

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Capot Chemical Co., Ltd

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Adamas Reagent, Ltd.

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Chemsky (shanghai) International Co.,Ltd

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Hunan Hui Bai Shi Biotechnology Co., Ltd.

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Hangzhou Yuhao Chemical Technology Co., Ltd

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T&W GROUP

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View Lastest Price from 5-Iodocytidine manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 5-Iodocytidine 1147-23-5
Price: US $0.00-0.00/G
Min. Order: 1G
Purity: 98%
Supply Ability: 2000
Release date: 2025-06-03

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Iodocytidine 1147-23-5
Price: US $0.00-0.00/g
Min. Order: 100g
Purity: 98%min
Supply Ability: 100kgs
Release date: 2021-09-06

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Iodocytidine 1147-23-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-23

1147-23-5, 5-IodocytidineRelated Search:

Cytidine-5'-triphosphate disodium salt dihydrate 1-beta-D-Arabinofuranosylcytosine hydrochloride 5-Azacytidine Cytarabine 5-Bromouridine 5-BROMOCYTIDINE 5-IODOCYTOSINE Cytidine 2''-DEOXY-5-IODOCYTIDINE (5-IODO-2''-DEOXYCYTIDINE: 5-IDC),2'-DEOXY-5-IODOCYTIDINE N4-DIISOBUTYLAMINOMETHYLIDENE-5'-O-(DIMETHOXYTRITYL)-5-IODO-2'-O-METHYLCYTIDINE 5-IODO-2'-O-METHYLCYTIDINE N4-(DIISOBUTYLAMINOMETHYLIDENE)-5-IODO-2'-O-METHYL-CYTIDINE 2''-DEOXY-2''-FLUORO-5-IODOCYTIDINE 5-Iodocytidine 5-IODOCYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM 2'-Deoxy-2'-methylene-5-iodocytidine 3'-Deoxy-5-iodocytidine 5-IODOCYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT

1-BETA-D-RIBOFURANOSYL-5-IODOCYTOSINE

1-D-Ribofuranosyl-5-iodocytosine

5-Iodo-D-cytidine

iodocytidine

5-IODOCYTIDINE,99+%

5-IC

4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-iodo-pyrimidin-2-one

4-azanyl-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-pyrimidin-2-one

4-aMino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyriMidin-2-one

4-AMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-iodopyriMidin-2(1H)-one

5-IODOCYTIDINE

4-Amino-2-hydroxy-5-iodo-1β-D-ribofuranosylpyrimidine

5-I-Cr

Cytidine, 5-iodo-

5-Iodocytidine USP/EP/BP

5-lodo-cytidine(5-I-Cr)

1147-23-5

C9H12IN3O5

5-FOA

Bases & Related Reagents

Nucleotides

Nucleosides-5-I Nucleosides