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5-Bromouridine

Product Name
5-Bromouridine
CAS No.
957-75-5
Chemical Name
5-Bromouridine
Synonyms
5-BrU;5-Br-rU;5-Br-Ur;5-Br-Uridine;5-bromo-uridin;5-BROMOURIDINE;5'-BROMOURIDINE;5-Bromo-D-uridine;Uridine, 5-bromo-;5-Bromouridine,98%
CBNumber
CB1683763
Molecular Formula
C9H11BrN2O6
Formula Weight
323.1
MOL File
957-75-5.mol
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5-Bromouridine Property

Melting point:
180-182 °C (dec.) (lit.)
alpha 
-11 º (c=2 in H2O)
Density 
1.9322 (rough estimate)
refractive index 
1.6520 (estimate)
storage temp. 
-20°C
solubility 
Water (Sonicated)
form 
Solid
pka
7.73±0.10(Predicted)
color 
Off-White
optical activity
[α]22/D 11°, c = 2 in H2O
Water Solubility 
Insoluble in water.
BRN 
33664
CAS DataBase Reference
957-75-5(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
YU7300000
10
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
850187
Product name
5-Bromouridine
Purity
98%
Packaging
250mg
Price
$45.3
Updated
2024/03/01
Sigma-Aldrich
Product number
850187
Product name
5-Bromouridine
Purity
98%
Packaging
1g
Price
$112
Updated
2024/03/01
TCI Chemical
Product number
B0666
Product name
5-Bromouridine
Purity
>99.0%(HPLC)
Packaging
1g
Price
$89
Updated
2024/03/01
TCI Chemical
Product number
B0666
Product name
5-Bromouridine
Purity
>99.0%(HPLC)
Packaging
100mg
Price
$25
Updated
2024/03/01
Alfa Aesar
Product number
A18507
Product name
5-Bromouridine, 98%
Packaging
0.25g
Price
$24.65
Updated
2024/03/01
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5-Bromouridine Chemical Properties,Usage,Production

Description

5-Bromouridine is an energy-related metabolite that is a precursor of uridine. 5-Bromouridine binds to the nuclear DNA in cells, where it can act as a transcriptional regulator. 5-Bromouridine is used in the treatment of malignant brain tumors, where it can inhibit tumor growth by binding to the dna of cancer cells and preventing the synthesis of proteins required for cell division.

Chemical Properties

WHITE FINE POWDER

Uses

5-Bromouridine is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry. It possesses anti-viral activity and inhibits the activity of viruses such as human immunodeficiency virus.

Uses

5-Bromouridine is a uridine (U829910) derivative and is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry.

Definition

ChEBI: A uridine having a bromo substituent at the 5-position.

Purification Methods

Recrystallise it from 96% EtOH. UV max 279nm (log  3.95)in 2O pH 1.9. RF in n -BuOH/AcOH/H2O (4:4:1) is 0.49; in n-BuOH/EtOH/H2O (40:11:9) it is 0.46 and in isoPrOH/25%NH3/H2O (7:1:2) it is 0.53 using Whatman No 1 paper. [Pryst.s & Sorm Collect Czech Chem Commmun 29 2956 1964, Beilstein 31 H 24.]

5-Bromouridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromouridine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Hongene Biotech Corporation
Tel
021-64757213
Fax
86-21-64700613
Email
info@hongene.com
Country
China
ProdList
672
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhu Huaren Science and Technology Co., Ltd.
Tel
0553-0553-5842013-801 18155347026
Fax
086-553-5843138
Email
sale@huarensh.com
Country
China
ProdList
296
Advantage
64
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
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View Lastest Price from 5-Bromouridine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Bromouridine 957-75-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
500kg/month
Release date
2021-07-28
Hebei Mojin Biotechnology Co., Ltd
Product
5-Bromouridine 957-75-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-10
Hebei Guanlang Biotechnology Co., Ltd.
Product
5-Bromouridine 957-75-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-06

957-75-5, 5-BromouridineRelated Search:


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  • 5-Bromouridine,98%
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  • 5-Bromo-D-uridine
  • 5-BROMO-URIDINE(5-BRU)
  • 5-BROMOURIDINE (5-BROMOURACIL-1-β-D-RIBOFURANOSIDE: 5-BRU)
  • 5-BROMOURIDINE extrapure
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  • 5-broMo-1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione
  • 5-Br-rU
  • 5-BroMo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
  • 5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3
  • 5-Br-Uridine
  • 5-BROMOURACIL-1-BETA-D-RIBOFURANOSIDE
  • (-)-5-BROMOURIDINE
  • 5'-BROMOURIDINE
  • 5-BROMOURIDINE
  • 5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1
  • 5-Br-Ur
  • 5-Bromouridine &gt
  • Uridine, 5-bromo-
  • 5-Bromouridine USP/EP/BP
  • 957-75-5
  • C9H11BrN2O6
  • C9H11N2O6Br
  • Specialty Synthesis
  • Oligonucleotide Synthesis
  • Nucleosides
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Biochemistry
  • Nucleosides and their analogs
  • Nucleosides, Nucleotides & Related Reagents