SOLANIDINE Property

Melting point:

212-214°C

alpha 

D21 -29° (c = 0.5 in chloroform)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly, Heated)

form 

Solid

color 

White to Off-White

LogP

7.100 (est)

Safety

Hazard Codes 

T+,Xn

Risk Statements 

23/24/25-53-22

Safety Statements 

2-13-45-36/37/39-22

RIDADR 

1544

WGK Germany 

3

RTECS 

WF0500000

HazardClass 

6.1(b)

PackingGroup 

III

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

SOLANIDINE Chemical Properties,Usage,Production

Uses

Soladine has been shown to display mutagenic properties in the liver, and is stored in the body for prolonged periods of time.

Definition

ChEBI: Solanidine is a steroid alkaloid fundamental parent, a 3beta-hydroxy-Delta(5)-steroid and a solanid-5-en-3-ol. It has a role as a plant metabolite and a toxin. It is a conjugate base of a solanidine(1+).

Purification Methods

Solanidine crystallises from CHCl3/MeOH, aqueous EtOH or aqueous MeOH as needles. TLC on Al2O3 plates using CH2Cl2/MeOH (98:2) gives a spot at RF 0.47. The hydrochloride crystallises from aqueous EtOH with m 345o(dec). The acetate crystallises from EtOH with m 208o. [Schreiber & Roensch Tetrahedron 21 6451965, Kessar et al. Tetrahedron 27 2153 1971, Reichestein & Reich Ann Rev Biochem 15 155 1946, Beilstein 21 III/IV 1398, 27 III/IV 2000.]