1-tert-Butylpiperazine
- Product Name
- 1-tert-Butylpiperazine
- CAS No.
- 38216-72-7
- Chemical Name
- 1-tert-Butylpiperazine
- Synonyms
- 1-T-BUTYLPIPERAZINE;N-T-BUTYLPIPERAZINE;N-TERT-BUTYLPIPERAZINE;1-tert-Butylpiperazine;1-tert-Butylpiperazine,97%;1-(tert-Butyl)piperazine 98+%;1-(tert-Butyl)piperazine, tech;1-(1,1-Dimethylethyl)piperazine;Piperazine, 1-(1,1-dimethylethyl)-;2-Methyl-2-(piperazin-1-yl)propane
- CBNumber
- CB3411496
- Molecular Formula
- C8H18N2
- Formula Weight
- 142.24
- MOL File
- 38216-72-7.mol
1-tert-Butylpiperazine Property
- Melting point:
- 32-35℃
- Boiling point:
- 85-87℃/22mm
- Density
- 0.890±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 9.27±0.10(Predicted)
- form
- Low Melting Solid
- color
- Colorless to yellow
- Sensitive
- Light, Air & Moisture Sensitive
- InChI
- InChI=1S/C8H18N2/c1-8(2,3)10-6-4-9-5-7-10/h9H,4-7H2,1-3H3
- InChIKey
- PVMNSAIKFPWDQG-UHFFFAOYSA-N
- SMILES
- N1(C(C)(C)C)CCNCC1
- CAS DataBase Reference
- 38216-72-7(CAS DataBase Reference)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN3259
- HazardClass
- 8
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H400Very toxic to aquatic life
- Precautionary statements
-
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B699805
- Product name
- 1-tert-Butylpiperazine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR5147
- Product name
- 1-(tert-Butyl)piperazine
- Purity
- 98+%
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
- Product number
- 3H32-1-Q4
- Product name
- 1-(tert-Butyl)piperazine
- Purity
- 98.0%
- Packaging
- 1g
- Price
- $23
- Updated
- 2021/12/16
- Product number
- 075266
- Product name
- 1-tert-Butylpiperazine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $178
- Updated
- 2021/12/16
- Product number
- V1661
- Product name
- N-tert-Butylpiperazine
- Packaging
- 25g
- Price
- $187
- Updated
- 2021/12/16
1-tert-Butylpiperazine Chemical Properties,Usage,Production
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 7331, 1994 DOI: 10.1016/0040-4039(94)85306-1
Synthesis
507-20-0
7542-23-6
38216-72-7
General procedure for the synthesis of N-tert-butylpiperazine from chlorinated tert-butane and compound (CAS:7542-23-6): 20 mmol of compound (1) and 150 mL of tetrahydrofuran were added to a 250 mL round bottom flask. A 50 mL acetonitrile solution of 20 mmol of tert-butyl chloride was slowly added dropwise with stirring at room temperature. The dropwise addition process was completed in about 2 hours. Stirring of the reaction mixture was continued for 2 hours. It was then heated to reflux and stirred for 5 h. After completion of the reaction, the reaction was cooled to room temperature, filtered, and the solid was washed with 10 mL of tetrahydrofuran and dried to give mono-substituted piperazinic acid dihydrochloride (5) (R=tert-butyl). The compound (5) was transferred to a 250 mL round bottom flask and 200 mL of tetrahydrofuran and an appropriate amount of base was added. The reaction was heated to reflux for 4 hours under stirring. After completion of the reaction, it was cooled to room temperature, filtered, and the filtrate was evaporated by solvent to remove the low-boiling components, and the product was collected by distillation to afford the light yellow oily liquid N-tert-butylpiperazine (6) (R=tert-butyl) in 92% yield (based on the amount of tert-butyl chloride fed).
References
[1] Patent: CN106083761, 2016, A. Location in patent: Paragraph 0024; 0025
1-tert-Butylpiperazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-tert-Butylpiperazine manufacturers
- Product
- 1-tert-Butylpiperazine 38216-72-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons
- Release date
- 2022-02-23
- Product
- 1-tert-Butylpiperazine 38216-72-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 654
- Release date
- 2019-09-01