ChemicalBook > CAS DataBase List > 1-tert-Butylpiperazine

1-tert-Butylpiperazine

Product Name
1-tert-Butylpiperazine
CAS No.
38216-72-7
Chemical Name
1-tert-Butylpiperazine
Synonyms
1-T-BUTYLPIPERAZINE;N-T-BUTYLPIPERAZINE;N-TERT-BUTYLPIPERAZINE;1-tert-Butylpiperazine;1-tert-Butylpiperazine,97%;1-(tert-Butyl)piperazine 98+%;1-(tert-Butyl)piperazine, tech;1-(1,1-Dimethylethyl)piperazine;Piperazine, 1-(1,1-dimethylethyl)-;2-Methyl-2-(piperazin-1-yl)propane
CBNumber
CB3411496
Molecular Formula
C8H18N2
Formula Weight
142.24
MOL File
38216-72-7.mol
More
Less

1-tert-Butylpiperazine Property

Melting point:
32-35℃
Boiling point:
85-87℃/22mm
Density 
0.890±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
9.27±0.10(Predicted)
form 
Low Melting Solid
color 
Colorless to yellow
Sensitive 
Light, Air & Moisture Sensitive
InChI
InChI=1S/C8H18N2/c1-8(2,3)10-6-4-9-5-7-10/h9H,4-7H2,1-3H3
InChIKey
PVMNSAIKFPWDQG-UHFFFAOYSA-N
SMILES
N1(C(C)(C)C)CCNCC1
CAS DataBase Reference
38216-72-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN3259
HazardClass 
8
HS Code 
2933599590
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B699805
Product name
1-tert-Butylpiperazine
Packaging
50mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR5147
Product name
1-(tert-Butyl)piperazine
Purity
98+%
Packaging
1g
Price
$21
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-Q4
Product name
1-(tert-Butyl)piperazine
Purity
98.0%
Packaging
1g
Price
$23
Updated
2021/12/16
Matrix Scientific
Product number
075266
Product name
1-tert-Butylpiperazine
Purity
95+%
Packaging
5g
Price
$178
Updated
2021/12/16
AK Scientific
Product number
V1661
Product name
N-tert-Butylpiperazine
Packaging
25g
Price
$187
Updated
2021/12/16
More
Less

1-tert-Butylpiperazine Chemical Properties,Usage,Production

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 7331, 1994 DOI: 10.1016/0040-4039(94)85306-1

Synthesis

507-20-0

7542-23-6

38216-72-7

General procedure for the synthesis of N-tert-butylpiperazine from chlorinated tert-butane and compound (CAS:7542-23-6): 20 mmol of compound (1) and 150 mL of tetrahydrofuran were added to a 250 mL round bottom flask. A 50 mL acetonitrile solution of 20 mmol of tert-butyl chloride was slowly added dropwise with stirring at room temperature. The dropwise addition process was completed in about 2 hours. Stirring of the reaction mixture was continued for 2 hours. It was then heated to reflux and stirred for 5 h. After completion of the reaction, the reaction was cooled to room temperature, filtered, and the solid was washed with 10 mL of tetrahydrofuran and dried to give mono-substituted piperazinic acid dihydrochloride (5) (R=tert-butyl). The compound (5) was transferred to a 250 mL round bottom flask and 200 mL of tetrahydrofuran and an appropriate amount of base was added. The reaction was heated to reflux for 4 hours under stirring. After completion of the reaction, it was cooled to room temperature, filtered, and the filtrate was evaporated by solvent to remove the low-boiling components, and the product was collected by distillation to afford the light yellow oily liquid N-tert-butylpiperazine (6) (R=tert-butyl) in 92% yield (based on the amount of tert-butyl chloride fed).

References

[1] Patent: CN106083761, 2016, A. Location in patent: Paragraph 0024; 0025

1-tert-Butylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-tert-Butylpiperazine Suppliers

China 124 Europe 2 Germany 3 India 5 Japan 1 Switzerland 1 United Kingdom 6 United States 20 Global 162
Shanghai Pullins Pharmaceutical Technology Co., LTD
Tel
021-68080657 15921562525
Email
37130379@qq.com
Country
China
ProdList
48
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Sichuan Guanghan Bio-Tech Co., Ltd
Tel
+86-28-86127071
Fax
+86-28-86127072
Email
info@sino-produce.com
Country
China
ProdList
406
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Wuhan Haizheng Industry & Trade Development Co. Ltd
Tel
027-8866 0053/88660577/88660578
Fax
027-8899 1911
Country
China
ProdList
1073
Advantage
55
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2151
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
15928766785 15928766785
Fax
QQ961458712
Email
wupengcheng@astatech.cn
Country
China
ProdList
1987
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
023-13650506873 19923294409
Email
xingcanyaoye@sina.com
Country
China
ProdList
1604
Advantage
58
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
2598
Advantage
60
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9858
Advantage
58
Changsha Jing Kang New Material Technology Co., Ltd.
Tel
0733-0731-85118349 18874718518
Fax
0731-85118349
Email
877634463@qq.com
Country
China
ProdList
1965
Advantage
50
Bellen Chemistry Co., Ltd.
Tel
010-60400365-8001 15910885229
Fax
010-60400361
Email
service@bellenchem.com
Country
China
ProdList
4514
Advantage
60
SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
QQ:2746983436
Email
sales@sano-chem.com
Country
China
ProdList
3795
Advantage
55
Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q2635253576
Fax
QQ3382968513
Email
hailey@shsendpharm.com
Country
China
ProdList
1984
Advantage
55
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
sales@chemwill.com
Country
China
ProdList
1974
Advantage
58
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Chengdu HuaNa Chemicals Co., Ltd.
Tel
028-86612776; 13699069380
Fax
-
Email
515238037@qq.com
Country
China
ProdList
968
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Nanjing SynTitan Pharmaceutical Co., Ltd.
Tel
025-57027686 17372956142
Fax
025-57027686
Email
li_lan@syntitan.com
Country
China
ProdList
9998
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.
Tel
029-88380327 17691182729
Fax
029-88380327
Email
1018@dideu.com
Country
China
ProdList
2011
Advantage
58
Nanjing Chengqian Pharmaceutical Technology Co., Ltd.
Tel
025-52791040 18652036685
Email
haozhongwen@126.com
Country
China
ProdList
767
Advantage
58
Anhui xinying technology co., LTD
Tel
18505585965
Email
sales@xinying-chem.com
Country
China
ProdList
176
Advantage
58
Xi'an MC Biotech, Co., Ltd.
Tel
029-89275612 +8618991951683
Fax
8618991951683
Email
mcbio_sales@163.com
Country
China
ProdList
2251
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
sgtlifesciences pvt ltd
Tel
+8617013299288
Email
dj@sgtlifesciences.com
Country
China
ProdList
12373
Advantage
58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
sales@afinechem.com
Country
China
ProdList
15107
Advantage
58
More
Less

View Lastest Price from 1-tert-Butylpiperazine manufacturers

Dideu Industries Group Limited
Product
1-tert-Butylpiperazine 38216-72-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons
Release date
2022-02-23
Career Henan Chemical Co
Product
1-tert-Butylpiperazine 38216-72-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 654
Release date
2019-09-01

38216-72-7, 1-tert-ButylpiperazineRelated Search:

tert-Butyldimethylsilyl chloride 2-tert-Butylphenol 4-tert-Butylcatechol tert-Butyl methyl ether tert-Butylbenzene tert-Butyl hydroperoxide Methyl 4-tert-butylbenzoate 4-tert-Butylphenol DI-TERT-BUTYL ETHER tert-Butyl piperazin-1-ylacetate dihydrochloride tert-Butyl 1-piperazinecarboxylate 2-TERT-BUTYLPYRAZINE 2-METHYL-2-[4-(4-NITROPHENYL)PIPERAZINO]PROPANENITRILE 2-METHYL-2-(4-PHENYLPIPERAZINO)PROPANENITRILE 2-(4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]PIPERAZINO)-2-METHYLPROPANENITRILE Recombinant Human Telomerase 1-(1-Piperazinyl)adamantane dihydrochloride 1-tert-Butylpiperazine

  • 2-Methyl-2-(piperazin-1-yl)propane
  • Piperazine, 1-(1,1-dimethylethyl)-
  • N-TERT-BUTYLPIPERAZINE
  • N-T-BUTYLPIPERAZINE
  • 1-T-BUTYLPIPERAZINE
  • 1-tert-Butylpiperazine
  • 1-(tert-Butyl)piperazine 98+%
  • 1-(tert-Butyl)piperazine, tech
  • 1-tert-Butylpiperazine,97%
  • 1-tert-Butylpiperazine ISO 9001：2015 REACH
  • 1-(1,1-Dimethylethyl)piperazine
  • 38216-72-7
  • 1