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OXYTHIAMINE HYDROCHLORIDE

Product Name
OXYTHIAMINE HYDROCHLORIDE
CAS No.
614-05-1
Chemical Name
OXYTHIAMINE HYDROCHLORIDE
Synonyms
OXYTHIAMINE HCL;Oxythiamine Chloride HCl;OXYTHIAMINE HYDROCHLORIDE;Oxametholone Hydrochloride;OXYTHIAMINE CHLORIDE HYDROCHLORIDE;hydroxythiaminechloridehydrochloride;OXYTHIAMINE CHLORIDE HCL CRYSTALLINE;hyl)-4-methyl-,chloride,monohydrochloride;Thiamine Impurity 19(Oxythiamine Chloride HCl);Oxythiamine chloride hydrochloride, ≥95% (HPLC)
CBNumber
CB3428625
Molecular Formula
C12H17Cl2N3O2S
Formula Weight
338.25
MOL File
614-05-1.mol
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OXYTHIAMINE HYDROCHLORIDE Property

Melting point:
>190°C (subl.)
storage temp. 
-20°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Safety

WGK Germany 
3
RTECS 
XJ7034100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O4000
Product name
Oxythiamine chloride hydrochloride
Purity
≥95% (HPLC)
Packaging
1g
Price
$50.3
Updated
2024/03/01
Sigma-Aldrich
Product number
O4000
Product name
Oxythiamine chloride hydrochloride
Purity
≥95% (HPLC)
Packaging
5g
Price
$156
Updated
2024/03/01
Cayman Chemical
Product number
29953
Product name
Oxythiamine (chloride hydrochloride)
Packaging
1g
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
29953
Product name
Oxythiamine (chloride hydrochloride)
Packaging
25g
Price
$479
Updated
2024/03/01
Cayman Chemical
Product number
29953
Product name
Oxythiamine (chloride hydrochloride)
Packaging
5g
Price
$140
Updated
2024/03/01
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OXYTHIAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

thiamine antagonist

Uses

Oxythiamine chloride hydrochloride is suitable for use:

  • as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells
  • as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines
  • in the synthesis of oxythiamineH picrolonate salt

Definition

ChEBI: A hydrochloride obtained by combining oxythiamine chloride with one molar equivalent of hydrochloric acid.

General Description

Oxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.

Biochem/physiol Actions

Oxythiamine (OT) is a thiamine antagonist. It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms, especially those involving metalloproteinases (MMP). It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.

OXYTHIAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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OXYTHIAMINE HYDROCHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
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57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
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9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80

614-05-1, OXYTHIAMINE HYDROCHLORIDERelated Search:


  • 5-(2-HYDROXYETHYL)-3-(4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL)-4-METHYLTHIAZOLIUM CHLORIDE
  • 5-[2-HYDROXYETHYL]-3-[4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL]-4-METHYLTHIAZOLIUM CHLORIDE HYDROCHLORIDE
  • Oxametholone Hydrochloride
  • hydroxythiaminechloridehydrochloride
  • hyl)-4-methyl-,chloride,monohydrochloride
  • OXYTHIAMINE CHLORIDE HYDROCHLORIDE
  • OXYTHIAMINE HCL
  • OXYTHIAMINE HYDROCHLORIDE
  • OXYTHIAMINE CHLORIDE HCL CRYSTALLINE
  • 5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride
  • 5-[[5-(2-hydroxyethyl)-4-methyl-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride
  • 5-(2-Hydroxyethyl)-4-methyl-3-[(2-methyl-6-oxo-1,6-dihydro-5-pyrimidinyl)methyl]-1,3-thiazol-3-ium chloride hydrochloride (1:1:1)
  • 5-(2-Hydroxyethyl)-4-methyl-3-((2-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)methyl)thiazol-3-ium chloride hydrochloride
  • Thiamine Impurity 19(Oxythiamine Chloride HCl)
  • Oxythiamine Chloride HCl
  • Oxythiamine chloride hydrochloride, ≥95% (HPLC)
  • 614-05-1
  • C12H17Cl2N3O2S
  • C12H16ClN3O2SHCl
  • C12H16N3O2SClHCl
  • C12H16N3O2SClClH
  • Biochemistry
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