OXYTHIAMINE HYDROCHLORIDE
- Product Name
- OXYTHIAMINE HYDROCHLORIDE
- CAS No.
- 614-05-1
- Chemical Name
- OXYTHIAMINE HYDROCHLORIDE
- Synonyms
- OXYTHIAMINE HCL;Oxythiamine Chloride HCl;OXYTHIAMINE HYDROCHLORIDE;Oxametholone Hydrochloride;OXYTHIAMINE CHLORIDE HYDROCHLORIDE;hydroxythiaminechloridehydrochloride;OXYTHIAMINE CHLORIDE HCL CRYSTALLINE;hyl)-4-methyl-,chloride,monohydrochloride;Thiamine Impurity 19(Oxythiamine Chloride HCl);Oxythiamine chloride hydrochloride, ≥95% (HPLC)
- CBNumber
- CB3428625
- Molecular Formula
- C12H17Cl2N3O2S
- Formula Weight
- 338.25
- MOL File
- 614-05-1.mol
OXYTHIAMINE HYDROCHLORIDE Property
- Melting point:
- >190°C (subl.)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
Safety
- WGK Germany
- 3
- RTECS
- XJ7034100
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- O4000
- Product name
- Oxythiamine chloride hydrochloride
- Purity
- ≥95% (HPLC)
- Packaging
- 1g
- Price
- $50.3
- Updated
- 2024/03/01
- Product number
- O4000
- Product name
- Oxythiamine chloride hydrochloride
- Purity
- ≥95% (HPLC)
- Packaging
- 5g
- Price
- $156
- Updated
- 2024/03/01
- Product number
- 29953
- Product name
- Oxythiamine (chloride hydrochloride)
- Packaging
- 1g
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 29953
- Product name
- Oxythiamine (chloride hydrochloride)
- Packaging
- 25g
- Price
- $479
- Updated
- 2024/03/01
- Product number
- 29953
- Product name
- Oxythiamine (chloride hydrochloride)
- Packaging
- 5g
- Price
- $140
- Updated
- 2024/03/01
OXYTHIAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
thiamine antagonist
Uses
Oxythiamine chloride hydrochloride is suitable for use:
- as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells
- as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines
- in the synthesis of oxythiamineH picrolonate salt
Definition
ChEBI: A hydrochloride obtained by combining oxythiamine chloride with one molar equivalent of hydrochloric acid.
General Description
Oxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.
Biochem/physiol Actions
Oxythiamine (OT) is a thiamine antagonist. It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms, especially those involving metalloproteinases (MMP). It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.
OXYTHIAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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