4,4'-DIMETHOXYSTILBENE Property

Melting point:

213-215 °C

Boiling point:

323.02°C (rough estimate)

Density 

1.1228 (rough estimate)

refractive index 

1.4700 (estimate)

storage temp. 

Amber Vial, Refrigerator, Under inert atmosphere

solubility 

Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated)

form 

Glistening Flakes

color 

White

Stability:

Light Sensitive

Safety

Hazard Codes 

Xi

Risk Statements 

36/38

Safety Statements 

37/39-26

HS Code 

29379000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

4,4'-DIMETHOXYSTILBENE Chemical Properties,Usage,Production

Chemical Properties

WHITE GLISTENING FLAKES

Uses

4,4''-Dimethoxystilbene is an intermediate in the synthesis of nonsteroidal, selective estrogen receptor modulator (SERM), Raloxifene (R100000).

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 4158, 1961 DOI: 10.1021/jo01068a638
Synthetic Communications, 21, p. 841, 1991 DOI: 10.1080/00397919108019767
Tetrahedron, 43, p. 2741, 1987 DOI: 10.1016/S0040-4020(01)86879-4