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(+)-PULEGONE

Product Name
(+)-PULEGONE
CAS No.
89-82-7
Chemical Name
(+)-PULEGONE
Synonyms
PULEGONE;(R)-PULEGONE;PULEGON;P-MENTH-4(8)-EN-3-ONE;2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE;FEMA 2963;NSC 15334;D-PULEGONE;d-Puregone;(+)-PULEONE
CBNumber
CB3448348
Molecular Formula
C10H16O
Formula Weight
152.23
MOL File
89-82-7.mol
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(+)-PULEGONE Property

Melting point:
<=25°C
alpha 
D20 +21°; 20546 +28.2°
Boiling point:
224 °C(lit.)
Density 
0.937 g/mL at 25 °C(lit.)
vapor pressure 
138 mm Hg ( 25 °C)
refractive index 
n20/D 1.488
FEMA 
2963 | PULEGONE
Flash point:
185 °F
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Liquid
color 
Clear colorless to yellow
Specific Gravity
0.94
Odor
at 100.00 %. peppermint camphor fresh herbal buchu
Odor Type
minty
optical activity
[α]20/D +23.5°, neat
λmax
255nm(lit.)
Merck 
14,7937
JECFA Number
753
BRN 
2040703
Dielectric constant
9.5(20℃)
InChIKey
NZGWDASTMWDZIW-MRVPVSSYSA-N
LogP
2.56
CAS DataBase Reference
89-82-7(CAS DataBase Reference)
IARC
2B (Vol. 108) 2016
EPA Substance Registry System
d-Pulegone (89-82-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
23-24/25
RIDADR 
2810
WGK Germany 
3
RTECS 
OT0261000
10-23
HS Code 
2914 29 00
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
89-82-7(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 470 mg/kg LD50 dermal Rabbit 3090 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W296309
Product name
(R)-(+)-Pulegone
Purity
≥90%
Packaging
100g
Price
$132
Updated
2024/03/01
Sigma-Aldrich
Product number
W296309
Product name
(R)-(+)-Pulegone
Purity
≥90%
Packaging
1kg
Price
$968
Updated
2024/03/01
Sigma-Aldrich
Product number
CRM40371
Product name
(+)-Pulegone solution
Purity
certified reference material, 2000?μg/mL in methanol, ampule of 1?mL
Packaging
1mL
Price
$82.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.18665
Product name
(R)-(+)-Pulegone
Purity
for synthesis
Packaging
10ml
Price
$135
Updated
2024/03/01
Sigma-Aldrich
Product number
04620590
Product name
(+)-Pulegone
Purity
primary pharmaceutical reference standard
Packaging
100mg
Price
$384
Updated
2024/03/01
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(+)-PULEGONE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Chemical Properties

Pulegone.has.a.pleasant.odor,somewhat.similar.to.peppermint.and.camphor.

Occurrence

The l-form is found in the essential oils of Agastache formosana, Israeli orange, Barosma betulina and Barosma crenulata; the d-form is the most abundant and is found in pennyroyal oils. Also reported found in rabbiteye blueberry, black currants (buds), fresh blackberry, heated blackberry, peppermint oil, corn mint oil, spearmint oil, Scotch spearmint oil, other Mentha oils, thyme, black tea, origanum, Ocimum basilicum varieties, rosemary, lemon balm, buchu oil, anise hyssop, sweet grass oil and German chamomile oil.

Uses

A monoterpene, commonly found in the essential oils of Nepeta cataria (Catnip).

Definition

ChEBI: The (5R)-enantiomer of p-menth-4(8)-en-3-one.

Aroma threshold values

Detection:.130.ppb..Aroma.characteristics.at.1.0%:.minty.cooling,.herbal.green,.sweet,.clean.spicy,.with. wintergreen.nuances.

Taste threshold values

Taste characteristics at 20 ppm: minty, terpy, cooling, woody pine, citrus lime, with fresh green peppermint notes.

General Description

(R)-(+)-Pulegone, a monoterpene ketone found in the essential oil of pennyroyal, can induce abortion.

Biochem/physiol Actions

Taste at 20 ppm

Synthesis

Isolated.from.pennyroyal.oil.(Moroccan.or.Spanish);.synthesis.from.3-methyl.cyclohexanone..The.structure.has.been.defined. by.the.work.of.several.authors;.the.d-,.l-.and.dl-forms.are.known;.the.dl-form.is.prepared.synthetically.and.is.not.found.in.nature.

target

GABA Receptor

Purification Methods

Purify pulegone via the semicarbazone which has m 174o (from MeOH) and [] D +68.2o (c 1, CHCl3). Fractionally distil it in vacuo. [Short & Read J Chem Soc 1309 1939]. [Erskine & Waight J Chem Soc 3425 1960, cf Ort Org Synth 65 203 1987, Beilstein 7 III 334, 7 IV 188.]

(+)-PULEGONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-PULEGONE Suppliers

Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from (+)-PULEGONE manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
(+)-PULEGONE 89-82-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31
Hebei Yanxi Chemical Co., Ltd.
Product
(+)-PULEGONE 89-82-7
Price
US $20.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-03
Hebei Mojin Biotechnology Co., Ltd
Product
(+)-PULEGONE 89-82-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-09

89-82-7, (+)-PULEGONERelated Search:


  • (R)-(+)-P-MENTH-4(8)-EN-3-ONE
  • (R)-P-MENTH-4(8)-EN-3-ONE
  • (R)-(+)-PULEGONE
  • (R)-PULEGONE
  • (R)-(+)-5-METHYL-2-ISOPROPYLIDENCYCLOHEXANONE
  • (R)-2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE
  • R-(+)-2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE
  • PULEGON
  • (+)-PULEGONE
  • PULEGONE
  • PULEGONE, R-(+)-
  • P-METNH-4(8)-EN-3-ONE
  • (+)-P-MENTH-4(8)-EN-3-ONE
  • P-MENTH-4(8)-EN-3-ONE
  • (r)-(+)-p-menth-4(8)-en-3-on
  • (r)-cyclohexanon
  • (+)-1-ISOPROPYLIDENE-4-METHYL-2-CYCLOHEXANONE
  • 2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE
  • (+)-1-METHYL-4-ISOPROPYLIDENE-3-CYCLOHEXANONE
  • (R)-(+)-PULEGONE, TECH., 85%
  • (R)-(+)-PULEGONE 85+%
  • (+)-PULEGONE, TERPENE STANDARD
  • (+)-4(8)-Para-menthen-3-one
  • (1R)-(+)-p-Menth-4(8)-en-3-one
  • Pulegone, pract., 92%
  • PULEGONE, S-(-)-(SG)
  • DELTA-PULEGONE
  • DEXTRO-PULEGONE
  • R-(+)-PARA-MENTH-4(8)-EN-3-ONE
  • R-(+)-PULEGONE WITH GC
  • d-PULEGONE, NATURAL
  • (+)-Pulegone, (R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one, p-Menth-4(8)-en-3-one
  • (R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one
  • (R)-5-Methyl-2-(1-methylethylidene)cyclohexan-1-one
  • (R)-5-Methyl-2-(1-methylethylidene)cyclohexanone
  • Pulegone,92%,pract.
  • PULEGONE, R-(+)-(SG)
  • (+)-Pulegone ,98%
  • Pulegone, pract., 92% 100GR
  • (+)-Pulegone,(R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one
  • (R)-(+)-Pulegone,(+)-Pulegone, (R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one, p-Menth-4(8)-en-3-one
  • PULEGONE, TECH
  • (+)-Pulegone ,90%
  • (theta)-cyclohexanon
  • 3-Methyl-6-isopropylidenecyclohexanone
  • 4(8)-p-Menthen-3-one
  • 5-methyl-2-(1-methylethylidene)-,(5R)-Cyclohexanone
  • Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (R)-
  • Cyclohexanone,5-methyl-2-(1-methylethylidene)-,(5R)-
  • Cyclohexanone,5-methyl-2-(1-methylethylidene)-,(R)-
  • d-p-Menth-4(8)-en-3-one
  • p-Menth-4(8)-en-3-one, (R)-(+)-
  • p-Menth-4(8)-en-3-one,(R)-(+)-
  • Pulegone, (d)
  • D-PULEGONE
  • FEMA 2963
  • (5R)-5-Methyl-2-(1-Methylethylidene)cyclohexanone
  • NSC 15334