ChemicalBook > CAS DataBase List > (+)-MENTHOL

(+)-MENTHOL

Product Name
(+)-MENTHOL
CAS No.
15356-60-2
Chemical Name
(+)-MENTHOL
Synonyms
(1S,2R,5S)-2-ISOPROPYL-5-METHYLCYCLOHEXANOL;C00553;(1S,2R,5S)-;(+)-menthol;MENTHOL, (+)-;dextro-menthol;D-P-MENTHAN-3-OL;(1S)-(+)-menthol;(+)-p-Menthan-3-ol;(+)-Menthol solution
CBNumber
CB4116411
Molecular Formula
C10H20O
Formula Weight
156.27
MOL File
15356-60-2.mol
More
Less

(+)-MENTHOL Property

Melting point:
43-44 °C (lit.)
Boiling point:
103-104 °C/9 mmHg (lit.)
Density 
0.890
vapor pressure 
0.8 mm Hg ( 20 °C)
refractive index 
50 ° (C=10, EtOH)
Flash point:
196 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
15.30±0.60(Predicted)
color 
Colourless to Off-White Oil
Odor
mentholic
optical activity
[α]23/D +48°, c = 10 in ethanol
Water Solubility 
Soluble in methanol (almost transparency), chloroform, alcohols, water (456 mg/L at 25°C), and ether.
BRN 
1902292
Dielectric constant
3.2(Ambient)
InChI
1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m0/s1
InChIKey
NOOLISFMXDJSKH-AEJSXWLSSA-N
SMILES
CC(C)[C@H]1CC[C@H](C)C[C@@H]1O
LogP
3.15 at 25℃
CAS DataBase Reference
15356-60-2(CAS DataBase Reference)
EPA Substance Registry System
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5S)- (15356-60-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
2
RTECS 
OT0700000
TSCA 
TSCA listed
HS Code 
29061100
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
224464
Product name
(1S,2R,5S)-(+)-Menthol
Purity
99%
Packaging
10g
Price
$75.1
Updated
2025/07/31
Sigma-Aldrich
Product number
224464
Product name
(1S,2R,5S)-(+)-Menthol
Purity
99%
Packaging
50g
Price
$261
Updated
2025/07/31
Sigma-Aldrich
Product number
CRM40474
Product name
(+)-Menthol solution
Purity
certified reference material, 2000?μg/mL in methanol, ampule of 1?mL
Packaging
1mL
Price
$100
Updated
2024/03/01
TCI Chemical
Product number
M3170
Product name
(+)-Menthol
Purity
>99.0%(GC)
Packaging
25g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
M3170
Product name
(+)-Menthol
Purity
>99.0%(GC)
Packaging
100g
Price
$125
Updated
2024/03/01
More
Less

(+)-MENTHOL Chemical Properties,Usage,Production

Description

(+)-Menthol is a monoterpene alcohol that has been found in Cannabis and has antifungal activity. It inhibits the growth of F. verticillioides (MIC = 1.5 mM). Unlike (–)-menthol, (+)-menthol does not exhibit analgesia, antibacterial, anticancer, or cholinesterase inhibitory activities.

Chemical Properties

(+)-MENTHOL is white low melting solid

Uses

(+)-MENTHOL is used for oral gel patch or film containing herb extracts or Chinese medicine, fruit extract, spearmint, and menthol for smoking cessation.

Uses

(1S,2R,5S)-(+)-menthol can undergo acylation with acid anhydrides in the presence of trimethylsilyl trifluoromethanesulfonate to form the corresponding acylated products.

Definition

ChEBI: (+)-menthol is a p-menthan-3-ol which has (1S,2R,5S)-stereochemistry. In contrast to (-)-menthol, the (+)-enantiomer occurs only rarely in nature. It is an enantiomer of a (-)-menthol.

General Description

(1S,2R,5S)-(+)-menthol is a chiral secondary alcohol. Its alcohol group can be protected as 2-tetrahydrofuranyl ether by reacting with bromotrichloromethane and tetrahydrofuran.

Synthesis

Prod.: by Meerwein-Ponndorf-Verley reduction of l-Menthone, resuhing in approximately two-thirds d-Neomenthol plus one-third i-Menthol. It can also be produced by reduction of d-Menthone.

References

[1] JOSé S. DAMBOLENA . Effects of menthol stereoisomers on the growth, sporulation and fumonisin B1 production of Fusarium verticillioides[J]. Food Chemistry, 2010, 123 1: Pages 165-170. DOI: 10.1016/j.foodchem.2010.04.024
[2] GUY P.P. KAMATOU . Menthol: A simple monoterpene with remarkable biological properties[J]. Phytochemistry, 2013, 96: Pages 15-25. DOI: 10.1016/j.phytochem.2013.08.005

(+)-MENTHOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(+)-MENTHOL Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44802
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11777
Advantage
60
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9892
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
More
Less

View Lastest Price from (+)-MENTHOL manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
(+)-MENTHOL 15356-60-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2025-03-10
Apeloa production Co.,Limited
Product
D-Menthol 15356-60-2
Price
US $1.00/g
Min. Order
1g
Purity
0.98
Supply Ability
1000
Release date
2024-07-18
PNP Biotech Co. Ltd
Product
D-Menthol 15356-60-2
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2023-06-01

15356-60-2, (+)-MENTHOLRelated Search:


  • C00553
  • (+)-Menthol, (1S,2R,5S)-2-Isopropyl-5-methylcyclohexanol
  • (1S,3S,4R)-p-Menthane-3-ol
  • (1S,3S,4R)-p-Menthane-3α-ol
  • [1S,2R,5S,(+)]-2-Isopropyl-5-methylcyclohexan-1-ol
  • [1S-(1.alpha.,2.beta.,5.alpha.)]-p-Menthan-3-ol
  • Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5S)-
  • (1S,2R,5S)-
  • (1S,2R,5S)-5-Methyl-2-(propan-2-yl)cyclohexan-1-ol
  • D-P-MENTHAN-3-OL
  • MENTHOL, (+)-
  • (1S,2R,5S)-(+)-Menthol 99%
  • (1S,2R,5S)-2-ISOPROPYL-5-METHYLCYCLOHEXANOL
  • (1S,2R,5S)-(+)-MENTHOL
  • (+)-MENTHOL, TERPENE STANDARD
  • (1S,2R,5S)-(+)-MENTHOL, 99% (96% EE/GLC)
  • (+)-Menthol=D-Menthol
  • (1S)-(+)-menthol
  • 5-methyl-2-(1-methylethyl)-,[1S-(1.alpha.,2.beta.,5.alpha.)]-Cyclohexanol
  • 5-methyl-2-(1-methylethyl)-,[1s-(1alpha,2beta,5alpha)]-cyclohexano
  • (2R)-5-methyl-2-propan-2-yl-1-cyclohexanol
  • (1S,2R,5S)-(+)-Menthol, 99%, for synthesis
  • (+)-Menthol solution
  • (+)-p-Menthan-3-ol
  • dextro-menthol
  • (+)-menthol
  • TIANFUCHEM--15356-60-2--(+)-MENTHOL in stock
  • (1s,2r,5s)-5-methyl-2-(1-met
  • NOOLISFMXDJSKH-AEJSXWLSSA-N
  • mtricitabine Impurity 9
  • (+)-Menthol, ≥ 99.0%
  • Nano-Liposomal MENTHOL
  • Antazoline Impurity 12
  • D-Menthol, 10 mM in DMSO
  • (1<i>S</i>,2<i>R</i>,5<i>S</i>)-(+)-Menthol
  • 15356-60-2
  • Optical Resolution
  • Terpenes
  • for Resolution of Acids
  • Monocyclic Monoterpenes
  • Organic Building Blocks
  • MEA - MES
  • Analytical Standards
  • Alphabetic
  • Alcohols
  • Analytical Chromatography Product Catalog
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • chiral
  • Biochemistry
  • for Resolution of Acids
  • Monocyclic Monoterpenes
  • Optical Resolution
  • Synthetic Organic Chemistry
  • Terpenes