FOLIC ACID DIHYDRATE

Product Name: FOLIC ACID DIHYDRATE
CAS No.: 75708-92-8
Chemical Name: FOLIC ACID DIHYDRATE
Synonyms: FolicAcidB.P.;PGA DIHYDRATE;FOLIC ACID pure;FOLIC ACID DIHYDRATE;PTEROYLGLUTAMIC ACID;FOLIC ACID, 500MG, NEAT;VitaMin M or VitaMin Bc;FOLIC ACID DIHYDRATE 97%;PGA, Pteroylglutamic acid;PTEROYLGLUTAMIC ACID DIHYDRATE
CBNumber: CB3453412
Molecular Formula: C19H23N7O8
Formula Weight: 477.43
MOL File: 75708-92-8.mol

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FOLIC ACID DIHYDRATE Property

Melting point:: 250°C
storage temp.: Store at RT.
solubility: Aqueous Acid (Slightly), Aqueous Base (Slightly), DMSO (Slightly)
pka: pK1:8.26 (25°C)
form: Solid
color: Yellow to Dark Yellow
Water Solubility: Miscible with water.
Merck: 14,4221
BRN: 100781
CAS DataBase Reference: 75708-92-8

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Safety

WGK Germany: 3
RTECS: LP5425000
TSCA: Yes

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: F680328
Product name: FolicAcidDihydrate
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

Chem-Impex

Product number: 01422
Product name: Folicaciddihydrate,97.0-102.0%(Assay),meetsUSPspecifications
Purity: 97.0-102.0%(Assay)
Packaging: 250G
Price: $104.83
Updated: 2021/12/16

AK Scientific

Product number: 6515AF
Product name: Folicaciddihydrate
Packaging: 100g
Price: $67
Updated: 2021/12/16

Chem-Impex

Product number: 01422
Product name: Folicaciddihydrate,97.0-102.0%(Assay),meetsUSPspecifications
Purity: 97.0-102.0%(Assay)
Packaging: 5G
Price: $13.5
Updated: 2021/12/16

Chem-Impex

Product number: 01422
Product name: Folic acid dihydrate
Purity: 97.0-102.0% (Assay)
Packaging: 25G
Price: $15
Updated: 2021/12/16

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FOLIC ACID DIHYDRATE Chemical Properties,Usage,Production

Chemical Properties

Yellow to yellow-orange crystalline powd

Uses

Vitamin B9. A B-complex vitamin necessary for the body to produce red blood cellsFolic acid dehydrate is used to form non-covalent complexes with polyethylenimine. It is used for the delivery of genes, which finds application in gene therapy. It is a B-complex vitamin, which is necessary for the body to produce red blood cells.

Purification Methods

If paper chromatography indicates impurities, then recrystallise it from hot H2O or from dilute acid [Walker et al. J Am Chem Soc 70 19 1948]. Impurities may be removed by repeated extraction with n-BuOH of a neutral aqueous solution of folic acid (by suspending in H2O and adding N NaOH dropwise till the solid dissolves, then adjusting the pH to ~7.0-7.5) followed by precipitation with acid, filtration, or better collected by centrifugation and recrystallised form hot H2O. [Blakley Biochem J 65 331 1975, Kalifa et al. Helv Chim Acta 6 1 2739 1978.] Chromatography on cellulose followed by filtration through charcoal has also been used to obtain pure acid. [Sakami & Knowles Science 129 274 1959.] UV: max 247 and 296nm ( 12,800 and 18,700) in H2O pH 1.0; 282 and 346nm ( 27.600 and 7,200) in H2O pH 7.0; 256, 284 and 366nm ( 24600, 24,500 and 86,00) in H2O pH 13 [Rabinowitz in The Enzymes (Boyer et al. Eds), 2 185 1960]. [Beilstein 26 III/IV 3944.]

FOLIC ACID DIHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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FOLIC ACID DIHYDRATE Suppliers

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