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FOLIC ACID DIHYDRATE

Product Name
FOLIC ACID DIHYDRATE
CAS No.
75708-92-8
Chemical Name
FOLIC ACID DIHYDRATE
Synonyms
FolicAcidB.P.;PGA DIHYDRATE;FOLIC ACID pure;FOLIC ACID DIHYDRATE;PTEROYLGLUTAMIC ACID;FOLIC ACID, 500MG, NEAT;VitaMin M or VitaMin Bc;FOLIC ACID DIHYDRATE 97%;PGA, Pteroylglutamic acid;PTEROYLGLUTAMIC ACID DIHYDRATE
CBNumber
CB3453412
Molecular Formula
C19H23N7O8
Formula Weight
477.43
MOL File
75708-92-8.mol
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FOLIC ACID DIHYDRATE Property

Melting point:
250°C
storage temp. 
Store at RT.
solubility 
Aqueous Acid (Slightly), Aqueous Base (Slightly), DMSO (Slightly)
pka
pK1:8.26 (25°C)
form 
Solid
color 
Yellow to Dark Yellow
Water Solubility 
Miscible with water.
Merck 
14,4221
BRN 
100781
CAS DataBase Reference
75708-92-8
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Safety

WGK Germany 
3
RTECS 
LP5425000
TSCA 
Yes
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
A14300
Product name
Folic acid dihydrate, 97%
Packaging
25g
Price
$67.65
Updated
2024/03/01
Alfa Aesar
Product number
A14300
Product name
Folic acid dihydrate, 97%
Packaging
100g
Price
$231
Updated
2024/03/01
TRC
Product number
F680328
Product name
FolicAcidDihydrate
Packaging
2.5g
Price
$75
Updated
2021/12/16
Chem-Impex
Product number
01422
Product name
Folicaciddihydrate,97.0-102.0%(Assay),meetsUSPspecifications
Purity
97.0-102.0%(Assay)
Packaging
250G
Price
$104.83
Updated
2021/12/16
Chem-Impex
Product number
01422
Product name
Folic acid dihydrate
Purity
97.0-102.0% (Assay)
Packaging
1KG
Price
$260
Updated
2021/12/16
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FOLIC ACID DIHYDRATE Chemical Properties,Usage,Production

Chemical Properties

Yellow to yellow-orange crystalline powd

Uses

Vitamin B9. A B-complex vitamin necessary for the body to produce red blood cellsFolic acid dehydrate is used to form non-covalent complexes with polyethylenimine. It is used for the delivery of genes, which finds application in gene therapy. It is a B-complex vitamin, which is necessary for the body to produce red blood cells.

Purification Methods

If paper chromatography indicates impurities, then recrystallise it from hot H2O or from dilute acid [Walker et al. J Am Chem Soc 70 19 1948]. Impurities may be removed by repeated extraction with n-BuOH of a neutral aqueous solution of folic acid (by suspending in H2O and adding N NaOH dropwise till the solid dissolves, then adjusting the pH to ~7.0-7.5) followed by precipitation with acid, filtration, or better collected by centrifugation and recrystallised form hot H2O. [Blakley Biochem J 65 331 1975, Kalifa et al. Helv Chim Acta 6 1 2739 1978.] Chromatography on cellulose followed by filtration through charcoal has also been used to obtain pure acid. [Sakami & Knowles Science 129 274 1959.] UV: max 247 and 296nm ( 12,800 and 18,700) in H2O pH 1.0; 282 and 346nm ( 27.600 and 7,200) in H2O pH 7.0; 256, 284 and 366nm ( 24600, 24,500 and 86,00) in H2O pH 13 [Rabinowitz in The Enzymes (Boyer et al. Eds), 2 185 1960]. [Beilstein 26 III/IV 3944.]

FOLIC ACID DIHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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FOLIC ACID DIHYDRATE Suppliers

Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973186 4009686088
Email
3193328036@qq.com
Country
China
ProdList
18338
Advantage
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Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8025
Advantage
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Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
21090
Advantage
60
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
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Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44458
Advantage
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Hubei zhonglong Kangsheng Fine Chemical Co., Ltd
Tel
027-027-83850178 18162590268
Fax
027-83850178
Email
1984393783@qq.com
Country
China
ProdList
3722
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Shanghai Haohong Scientific Co., Ltd.
Tel
400-400-8210725
Email
malulu@leyan.com
Country
China
ProdList
39953
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Nantong Zhonghe Chemical New Materials Co., Ltd
Tel
13003551299 13003551299
Email
2369399482@qq.com
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China
ProdList
7566
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
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58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd
Tel
13915962545
Email
2881759498@qq.com
Country
China
ProdList
2033
Advantage
58
SUZHOU SENFEIDA CHEMICAL CO.,LTD
Tel
+86-0512-83500002 +8615195660023
Email
sales@senfeida.com
Country
China
ProdList
23046
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58
Shanghai Jingke Chemical Technology Co., Ltd.
Tel
--
Fax
--
Email
jingkehuaxue@163.com
Country
CHINA
ProdList
6972
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Shanghai Haring Biotechnology Co., Ltd.
Tel
--
Fax
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Email
1815786809@qq.com
Country
CHINA
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4102
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Shanghai Qiaoyu Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
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6890
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Shanghai Shifeng Biological Technology Co., Ltd.
Tel
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Email
2279790755@qq.com
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CHINA
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5572
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Nanjing Senbega Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
zhouqi@sbjbio.com
Country
CHINA
ProdList
6809
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Guangzhou WeiBo Chemical Co., Ltd.
Tel
--
Fax
--
Email
weibochem@163.com
Country
China
ProdList
6187
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67
GuangZhou Pan-Acer Trading Limited
Tel
--
Fax
--
Email
info@fanhongtl.com
Country
China
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212
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Advanced Technology & Industrial Co., Ltd.
Tel
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Fax
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China
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6523
Advantage
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