ChemicalBook > CAS DataBase List > 8-HYDROXYOCTANOIC ACID

8-HYDROXYOCTANOIC ACID

Product Name: 8-HYDROXYOCTANOIC ACID
CAS No.: 764-89-6
Chemical Name: 8-HYDROXYOCTANOIC ACID
Synonyms: 8-hydroxyoctanoate;8-HYDROXYOCTANSURE;8-hydroxyoctanoicaci;8-HYDROXYCAPRYLIC ACID;8-HYDROXYOCTANOIC ACID;Octanoic acid, 8-hydroxy-;8-Hydroxyoctanoic acid,90%;8-Hydroxyoctanoic acid 98% (T)
CBNumber: CB3458316
Molecular Formula: C8H16O3
Formula Weight: 160.21
MOL File: 764-89-6.mol

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8-HYDROXYOCTANOIC ACID Property

Melting point:: 59-63 °C
Boiling point:: 130°C/1mm
Density: 1.0227 (rough estimate)
refractive index: 1.4370 (estimate)
storage temp.: Inert atmosphere,Room Temperature
pka: 4.77±0.10(Predicted)
form: crystalline powder
color: White
BRN: 1237092
LogP: 0.900 (est)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
F: 10-21
HS Code: 2918199890

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 55999
Product name: 8-Hydroxyoctanoic acid
Purity: 98% (T)
Packaging: 100mg
Price: $103
Updated: 2023/01/07

TCI Chemical

Product number: H1818
Product name: 8-Hydroxyoctanoic Acid
Purity: min. 98.0 %
Packaging: 250MG
Price: $64
Updated: 2025/07/31

TCI Chemical

Product number: H1818
Product name: 8-Hydroxyoctanoic Acid
Purity: min. 98.0 %
Packaging: 1G
Price: $159
Updated: 2025/07/31

TRC

Product number: H950885
Product name: 8-Hydroxyoctanoic acid
Packaging: 2.5g
Price: $160
Updated: 2021/12/16

Matrix Scientific

Product number: 004853
Product name: 8-Hydroxyoctanoic acid
Purity: 95%
Packaging: 1g
Price: $132
Updated: 2021/12/16

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8-HYDROXYOCTANOIC ACID Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Uses

8-Hydroxyoctanoic Acid is an intermediate in the synthesis of mono-carboxy-isooctyl-phthalate (M525590). 8-Hydroxyoctanoic Acid is also used as a reagent in the synthesis of histone deacetylases (HDAC) inhibitors with an N-formyl hydroxylamine head group which are promising targets for cancer chemotherapy.

Definition

ChEBI: An omega-hydroxy fatty acid that is caprylic acid in which one of the hydrogens of the terminal methyl group is replaced by a hydroxy group.

General Description

8-Hydroxyoctanoic acid is one of the constituents of ‘‘Royal jelly′′ acid found in herbhoneys and genuine honeys.

Synthesis

629-41-4

764-89-6

GENERAL PROCEDURE: All catalytic activity testing experiments were carried out in Schlenk tubes (50 mL) equipped with a condenser. 8-Hydroxycaprylic acid (HCA) was prepared by HDO oxidation reaction in alkaline aqueous medium using H2O2 as oxidant. The typical reaction procedure was as follows: first, the aliphatic diol (0.5 mmol) was weighed and dispersed with catalyst (25 mg) in deionized water (3.5 mL) in a Schlenk tube. Subsequently, 30% H2O2 (0.75 mL) and 0.5 M NaOH (0.75 mL) were added to the above mixture. The Schlenk tubes were placed in an oil bath preheated to 353 K and reacted for different time intervals under continuous magnetic stirring (500 rpm). After completion of the reaction, a portion of the reaction solution was taken and diluted 20-fold with 10 mM aqueous H2SO4 and the catalyst was removed by passing it through a 0.20 μm filter (Milex-LG). The resulting filtrate was analyzed by high performance liquid chromatography (HPLC, WATERS 600) on an Aminex HPX-87H column (Bio-Rad Laboratories, Inc.) with a refractive index detector. An aqueous solution of 10 mM H2SO4 was used as the eluent at a flow rate of 0.5 mL/min, and the column temperature was maintained at 323 K. The conversion and yield were determined by the calibration curve method for commercial products.

References

[1] Catalysis Today, 2016, vol. 265, p. 231 - 239

8-HYDROXYOCTANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8-HYDROXYOCTANOIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 8-Hydroxyoctanoic acid 764-89-6
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50kg
Release date: 2025-06-24

PNP Biotech Co. Ltd

Product: 8-Hydroxyoctanoic acid 764-89-6
Price: US $0.00/KG
Min. Order: 25KG
Purity: 95%
Supply Ability: Inquiry
Release date: 2022-09-28

Honest Joy Holdings Limited

Product: 8-hydroxyoctanoicacid 764-89-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.5%
Supply Ability: 100 tons
Release date: 2022-01-14

764-89-6, 8-HYDROXYOCTANOIC ACIDRelated Search:

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8-HYDROXYOCTANOIC ACID

8-HYDROXYCAPRYLIC ACID

8-hydroxyoctanoate

8-HYDROXYOCTANSURE

8-Hydroxyoctanoic acid,90%

Octanoic acid, 8-hydroxy-

8-Hydroxyoctanoic acid 98% (T)

8-hydroxyoctanoicaci

764-89-6

C8H16O3

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