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FMOC-LYS(BOC)(ME)-OH

Product Name
FMOC-LYS(BOC)(ME)-OH
CAS No.
951695-85-5
Chemical Name
FMOC-LYS(BOC)(ME)-OH
Synonyms
Fmoc-Lys(Me,Boc);FMOC-LYS(ME,BOC)-OH;FMOC-LYS(BOC)(ME)-OH;FMOC-L-LYS(BOC, ME)-OH;Boc-L-Lys(Fmoc)(Me)-OH;FMOC-LYSINE(BOC)(ME)-OH;Fmoc-Lys(Me,Boc)-OH,95%;Fmoc-Lys(Me,Boc)-OH, >=97%;FMOC-LYS(BOC)(ME)-OH USP/EP/BP;Fmoc-Lys(Me,Boc)-OH Novabiochem
CBNumber
CB3465262
Molecular Formula
C27H34N2O6
Formula Weight
482.57
MOL File
951695-85-5.mol
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FMOC-LYS(BOC)(ME)-OH Property

Melting point:
85-87℃
Boiling point:
665.4±55.0 °C(Predicted)
Density 
1.200
storage temp. 
-20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
3.88±0.21(Predicted)
color 
White to off-white
InChIKey
JHMSFOFHTAYQLS-QHCPKHFHSA-N
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Safety

Hazard Codes 
Xi
WGK Germany 
WGK 2 water endangering
HS Code 
2924 29 70
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52106
Product name
Fmoc-Lys(Me,Boc)-OH
Purity
Novabiochem?
Packaging
500mg
Price
$1000
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52106
Product name
Fmoc-Lys(Me,Boc)-OH
Purity
Novabiochem?
Packaging
1g
Price
$1900
Updated
2024/03/01
TRC
Product number
F860973
Product name
Fmoc-lys(me,boc)-oh
Packaging
100mg
Price
$660
Updated
2021/12/16
Apolloscientific
Product number
OR2236
Product name
N6-Methyl-L-lysine,N6-BOC,N2-FMOCprotected
Packaging
1g
Price
$717
Updated
2021/12/16
Iris Biotech GmbH
Product number
FAA1448
Product name
Fmoc-L-Lys(Boc,Me)-OH
Packaging
1g
Price
$756
Updated
2021/12/16
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FMOC-LYS(BOC)(ME)-OH Chemical Properties,Usage,Production

Description

Fmoc-lys (BOC) (ME)-OH is a kind of protected form of lysine. Lysine is double-protected by butyloxycarbonyl (BOC) and 9H-fluoren-9-ylmethoxycarbon (FMOC). It is a derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. The Boc protecting group can be removed through the TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.

Uses

  1. Heterochromatin protein 1 (HP1) depends on trimethylation of H3 Lys 9; aggregation of chromatines depends on Lys methylation
  2. Fmoc-Lys(Boc, Me)-OH is useful for preparing monomethylated histone fragments utilized in studying the regulatory roles of methylated histones. Fmoc-Lys(Boc,Me)-OH can be coupled using standard activating procedures. The Boc group on the side epsilon nitrogen atom is removed with TFA, usually at the same time as the peptide is cleaved from the resin.
  3. Fmoc-Lys(Boc, Me)-OH is a novel derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting group occurs during the course of the TFA-mediated cleavage reaction.

General Description

Fmoc protected N-methylated lysine

References

http://www.chempep.com/ChemPep_Products2_Fmoc-Amino-Acid_Fmoc-Lys_Boc_Me_-OH.htm
https://en.wikipedia.org/wiki/Peptide_synthesis
Tung, C. L., et al. "A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation. " Chemical Communications 50.40(2014):5298-300.

FMOC-LYS(BOC)(ME)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-LYS(BOC)(ME)-OH Suppliers

Bejing Famous Pharmaceutical Technology Co., Ltd.
Tel
13331045123
Fax
86-10-80339217
Email
1963319514@qq.com
Country
China
ProdList
14229
Advantage
58
Shanghai GL Peptide Ltd.
Tel
+86-21-61263340; 17609490614 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8465
Advantage
55
Alabiochem Tech.Co., Ltd.
Tel
0512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
995
Advantage
59
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Sichuan Guanghan Bio-Tech Co., Ltd
Tel
+86-28-86127071
Fax
+86-28-86127072
Email
info@sino-produce.com
Country
China
ProdList
406
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7189
Advantage
65
Lavem Chine Pharm Company
Tel
28-86066080 18280039962
Fax
86-28-8527-5264
Email
sales@lavemc.com
Country
China
ProdList
214
Advantage
67
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View Lastest Price from FMOC-LYS(BOC)(ME)-OH manufacturers

Career Henan Chemical Co
Product
FMOC-LYS(BOC)(ME)-OH 951695-85-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-15

951695-85-5, FMOC-LYS(BOC)(ME)-OHRelated Search:


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  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoicaci
  • FMOC-LYS(BOC)(ME)-OH USP/EP/BP
  • Boc-L-Lys(Fmoc)(Me)-OH
  • N6-Boc-N2-Fmoc-N6-methyl-L-lysine
  • N2-(((9H-fluorene-9-yl)methoxy)oxo)-N6-(tertbutyloxyoxo)-N6-methyl-L-lysine
  • Fmoc-Lys(Me,Boc)-OH,95%
  • 951695-85-5
  • amino acids