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Z-VRPR-FMK (trifluoroacetate salt)

Product Name
Z-VRPR-FMK (trifluoroacetate salt)
Chemical Name
Z-VRPR-FMK (trifluoroacetate salt)
Synonyms
Z-VRPR-FMK (trifluoroacetate salt)
CBNumber
CB34666676
Molecular Formula
C33H50F4N10O8
Formula Weight
790.8059128
MOL File
Mol file
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Z-VRPR-FMK (trifluoroacetate salt) Property

solubility 
Water: Soluble
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19617
Product name
Z-VRPR-FMK (trifluoroacetate salt)
Purity
≥90%
Packaging
500μg
Price
$315
Updated
2024/03/01
Cayman Chemical
Product number
19617
Product name
Z-VRPR-FMK (trifluoroacetate salt)
Purity
≥90%
Packaging
1mg
Price
$566
Updated
2023/06/20
Tocris
Product number
4645
Product name
Z-VRPR-FMKtrifluoroacetatesalt
Packaging
500U
Price
$309
Updated
2021/12/16
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Z-VRPR-FMK (trifluoroacetate salt) Chemical Properties,Usage,Production

Description

Z-VRPR-FMK is a selective, irreversible inhibitor of the paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), an endopeptidase that targets BCL10 and reduces NF-κB activation in lymphocytes at 12.5 to 75 µM.1,2,3 Other MALT1 substrates that may be affected by Z-VRPR-FMK are TNFAIP3 and CYLD.3WARNING This product is not for human or veterinary use.

References

[1] FABIEN REBEAUD. The proteolytic activity of the paracaspase MALT1 is key in T cell activation[J]. Nature Immunology, 2008, 9 3: 272-281. DOI: 10.1038/ni1568
[2] JANNA HACHMANN. Mechanism and specificity of the human paracaspase MALT1.[J]. Biochemical Journal, 2012, 443 1: 287-295. DOI: 10.1042/bj20120035
[3] NORA FERNANDEZ-JIMENEZ. Coregulation and modulation of NFκB-related genes in celiac disease: uncovered aspects of gut mucosal inflammation.[J]. Human molecular genetics, 2014: 1298-1310. DOI: 10.1093/hmg/ddt520

Z-VRPR-FMK (trifluoroacetate salt) Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-VRPR-FMK (trifluoroacetate salt) Suppliers

Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19654
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6979
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58