Z-VRPR-FMK (trifluoroacetate salt)
- Product Name
- Z-VRPR-FMK (trifluoroacetate salt)
- Chemical Name
- Z-VRPR-FMK (trifluoroacetate salt)
- Synonyms
- Z-VRPR-FMK (trifluoroacetate salt)
- CBNumber
- CB34666676
- Molecular Formula
- C33H50F4N10O8
- Formula Weight
- 790.8059128
- MOL File
- Mol file
Z-VRPR-FMK (trifluoroacetate salt) Property
- solubility
- Water: Soluble
N-Bromosuccinimide Price
- Product number
- 19617
- Product name
- Z-VRPR-FMK (trifluoroacetate salt)
- Purity
- ≥90%
- Packaging
- 500μg
- Price
- $315
- Updated
- 2024/03/01
- Product number
- 19617
- Product name
- Z-VRPR-FMK (trifluoroacetate salt)
- Purity
- ≥90%
- Packaging
- 1mg
- Price
- $566
- Updated
- 2023/06/20
- Product number
- 4645
- Product name
- Z-VRPR-FMKtrifluoroacetatesalt
- Packaging
- 500U
- Price
- $309
- Updated
- 2021/12/16
Z-VRPR-FMK (trifluoroacetate salt) Chemical Properties,Usage,Production
Description
Z-VRPR-FMK is a selective, irreversible inhibitor of the paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), an endopeptidase that targets BCL10 and reduces NF-κB activation in lymphocytes at 12.5 to 75 µM.1,2,3 Other MALT1 substrates that may be affected by Z-VRPR-FMK are TNFAIP3 and CYLD.3WARNING This product is not for human or veterinary use.
References
[1] FABIEN REBEAUD. The proteolytic activity of the paracaspase MALT1 is key in T cell activation[J]. Nature Immunology, 2008, 9 3: 272-281. DOI: 10.1038/ni1568
[2] JANNA HACHMANN. Mechanism and specificity of the human paracaspase MALT1.[J]. Biochemical Journal, 2012, 443 1: 287-295. DOI: 10.1042/bj20120035
[3] NORA FERNANDEZ-JIMENEZ. Coregulation and modulation of NFκB-related genes in celiac disease: uncovered aspects of gut mucosal inflammation.[J]. Human molecular genetics, 2014: 1298-1310. DOI: 10.1093/hmg/ddt520
Z-VRPR-FMK (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Z-VRPR-FMK (trifluoroacetate salt) Suppliers
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