ChemicalBook > CAS DataBase List > BAY-850
BAY-850
- Product Name
- BAY-850
- CAS No.
- 2099142-76-2
- Chemical Name
- BAY-850
- Synonyms
- BAY-850;BAY850;BAY 850;BAY-850, 10 mM in DMSO;Benzamide, N-[(1R)-2-[(cis-4-aminocyclohexyl)amino]-1-[(4-cyanophenyl)methyl]ethyl]-2-chloro-4-methoxy-5-[5-[[[(1R)-1-(4-methylphenyl)ethyl]amino]methyl]-2-furanyl]-
- CBNumber
- CB34667613
- Molecular Formula
- C38H44ClN5O3
- Formula Weight
- 654.24
- MOL File
- 2099142-76-2.mol
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BAY-850 Property
- Boiling point:
- 771.2±60.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 62.5 mg/mL (95.53 mM)
- form
- Solid
- pka
- 13.14±0.46(Predicted)
- color
- White to light yellow
- Water Solubility
- H2O: 2mg/mL, clear
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML2748
- Product name
- BAY-850trihydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 5MG
- Price
- $286
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML2748
- Product name
- BAY-850 trihydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $919
- Updated
- 2024/03/01
Biorbyt Ltd
- Product number
- orb611273
- Product name
- BAY-850
- Purity
- >98%
- Packaging
- 100mg
- Price
- $1802
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611273
- Product name
- BAY-850
- Purity
- >98%
- Packaging
- 250mg
- Price
- $3580.2
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611273
- Product name
- BAY-850
- Purity
- >98%
- Packaging
- 1g
- Price
- $7136.6
- Updated
- 2021/12/16
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BAY-850 Chemical Properties,Usage,Production
Biological Activity
BAY-850 is a chemical probe th at targets ATPase family AAA domain-containing protein 2 (ATAD2) bromodomain (BD) with submicromolar affinity (Kd of 84.9 nM by MST and 120 nM by BROMOscan) and high selectivity over all other bromodomains tested (no BROMOscan hits at 10 μM). BAY-850 blocks ATAD2 BD from binding acetylated H4 peptide in cell-free assays (IC50 of 20 nM) and displaces full-length ATAD2 from chromatin in live cells (effctive conc. 1 μM by HTRF). To avoid potential unspecific off-target effects, concentrations above 5 μM are not recommended. BAY-460 is a companion control compound with strongly reduced ATAD2 inhibitory potency (IC50 = 16 μM by cell-based HTRF assay; no activity at 10 μM by BROMOscan).
BAY-850 Preparation Products And Raw materials
Raw materials
Preparation Products
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BAY-850 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 52924
- Advantage
- 58