ChemicalBook > CAS DataBase List > 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
- Product Name
- 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
- CAS No.
- 3031-94-5
- Chemical Name
- 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
- Synonyms
- ZMP;acadesine 5'-monophosphate;AICA-Riboside, 5′-Phosphate;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE;NSC 283955;NSC 292227;AICAR-5'-MP;Acaribonucleotide;AICAR-5'-MP / ZMP;aicaribonucleotide
- CBNumber
- CB3466890
- Molecular Formula
- C9H15N4O8P
- Formula Weight
- 338.21
- MOL File
- 3031-94-5.mol
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5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Property
- Melting point:
- 198-202°C dec.
- Boiling point:
- 845.3±75.0 °C(Predicted)
- Density
- 2.30±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly, Heated, Sonicated), Methanol (Slightly), Water (Slightly)
- pka
- 1.86±0.10(Predicted)
- form
- White to light pink solid
- color
- White to Pink
- optical activity
- [α]/D -69.0±3.0°, c = 0.1 in sodium bicarbonate
- Stability:
- Hygroscopic
- InChIKey
- UDYDDOATBNVEES-UUOKFMHZSA-N
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Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29349990
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- A1393
- Product name
- 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate
- Purity
- ≥93%
- Packaging
- 50mg
- Price
- $664
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 123041
- Product name
- AICA-Riboside, 5?-Phosphate
- Packaging
- 25mg
- Price
- $265
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 06595
- Product name
- 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate
- Purity
- analytical standard
- Packaging
- 25mg
- Price
- $744
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- A1393
- Product name
- 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate
- Purity
- ≥93%
- Packaging
- 100mg
- Price
- $1230
- Updated
- 2024/03/01
TRC
- Product number
- A611705
- Product name
- 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate
- Packaging
- 25mg
- Price
- $180
- Updated
- 2021/12/16
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5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Chemical Properties,Usage,Production
Chemical Properties
White Powder With Pink Tinge.
Uses
AICAR monophosphate is a 5′′-phosphorylated analog of cell permeable AICAR that mimics AMP. AICAR is an adenosine monophophate (AMP)-activated protein kinase (AMPK) activator/agonist.
Definition
ChEBI: AICA ribonucleotide is a 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative. It has a role as a cardiovascular drug, a plant metabolite, a human metabolite, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a 1-(phosphoribosyl)imidazolecarboxamide and an aminoimidazole. It is functionally related to an acadesine. It is a conjugate acid of a 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-).
General Description
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate (AICAR monophosphate) is an intermediate metabolite in the purine de novo synthesis pathway and a potent activator of the human AMP-activated protein kinase (AMPK) activity in vitro. It can play an important regulatory role.
Biochem/physiol Actions
A 5′-phosphorylated analog of cell permeable AICAR that mimics adenosine monophosphate (AMP). It is an AMP-activated protein kinase (AMPK) activator.In humans, 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5′-monophosphate (AICAR) is found to be accumulated in numerous metabolic diseases. It can increase the endurance of sedentary mice. AICAR exhibits antiproliferative effects. It can induce apoptosis of aneuploid cells.
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
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5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Suppliers
- Tel
- --
- Fax
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- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
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- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6581
- Advantage
- 61
- Tel
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- Fax
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- sales@carbonesci.com
- Country
- United Kingdom
- ProdList
- 6666
- Advantage
- 30
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View Lastest Price from 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE manufacturers
Shandong Huizhihan Supply Chain Co., Ltd
- Product
- AICA-Ribotide (NSC 283955) 3031-94-5
- Price
- US $0.00-0.00/Bottle
- Min. Order
- 1Bottle
- Purity
- 99%
- Supply Ability
- 2000
- Release date
- 2024-11-06
Shandong Huizhihan Supply Chain Co., Ltd
- Product
- AICA-Ribotide (NSC 283955) 3031-94-5
- Price
- US $0.00-0.00/Bottle
- Min. Order
- 1Bottle
- Purity
- 99%
- Supply Ability
- 2000
- Release date
- 2024-11-11
Wuhan Senwayer Century Chemical Co.,Ltd
- Product
- AICAR 3031-94-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 99% min
- Supply Ability
- 20 tons
- Release date
- 2024-07-08
3031-94-5, 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATERelated Search:
AICAR
5-Amino-4-imidazolecarboxamide
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE
3-ETHYL-3H-IMIDAZOLE-4-CARBALDEHYDE