5-Amino-4-imidazolecarboxamide

Description Reference

Product Name: 5-Amino-4-imidazolecarboxamide
CAS No.: 360-97-4
Chemical Name: 5-Amino-4-imidazolecarboxamide
Synonyms: aic;5-AMINO-1H-IMIDAZOLE-4-CARBOXAMIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE;4-AMINOIMIDAZOLE-5-CARBOXAMIDE;5-amino-1h-imidazole-4-carboxamid;ba2756;NSC 7784;diazol-c;4-Amino-5-imodazole;Temozolomide Impurity B
CBNumber: CB2438232
Molecular Formula: C4H6N4O
Formula Weight: 126.12
MOL File: 360-97-4.mol

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5-Amino-4-imidazolecarboxamide Property

Melting point:: 164-170 °C(lit.)
Boiling point:: 234.22°C (rough estimate)
Density: 1.3659 (rough estimate)
refractive index: 1.8500 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka: 11.97±0.10(Predicted)
form: Powder
color: White
Water Solubility: Soluble in DMSO, Methanol, Water.
InChI: InChI=1S/C4H6N4O/c5-3-2(4(6)9)7-1-8-3/h1H,5H2,(H2,6,9)(H,7,8)
InChIKey: DVNYTAVYBRSTGK-UHFFFAOYSA-N
SMILES: C1NC(N)=C(C(N)=O)N=1
CAS DataBase Reference: 360-97-4(CAS DataBase Reference)
EPA Substance Registry System: 1H-Imidazole-4-carboxamide, 5-amino- (360-97-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: NI3910000
TSCA: Yes
HS Code: 29332900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000735
Product name: Dacarbazine impurity B
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000735
Price: $150
Updated: 2024/03/01

Sigma-Aldrich

Product number: 552410
Product name: 5-Amino-4-imidazolecarboxamide
Purity: 95%
Packaging: 25g
Price: $193
Updated: 2024/03/01

Alfa Aesar

Product number: H66184
Product name: 4-Aminoimidazole-5-carboxamide, 95%
Packaging: 5g
Price: $36.65
Updated: 2024/03/01

Alfa Aesar

Product number: H66184
Product name: 4-Aminoimidazole-5-carboxamide, 95%
Packaging: 25g
Price: $140.65
Updated: 2024/03/01

Alfa Aesar

Product number: H66184
Product name: 4-Aminoimidazole-5-carboxamide, 95%
Packaging: 100g
Price: $444
Updated: 2021/12/16

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5-Amino-4-imidazolecarboxamide Chemical Properties,Usage,Production

Description

5-Amino-4-imidazolecarboxamide may be used in the synthesis of 4-(N′-benzoylcarbamoyl)amino-5-imidazolecarboxamide and 5-amino-1-β-D-ribosyl-4-imidazolecarboxamide-5′-phosphate (AICAR).It is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. When compounded with orotic acid, it is used to treat liver diseases.

Reference

3. Black, S. L., M. J. Black, and J. H. Mangum. "A rapid assay for 5-amino-4-imidazolecarboxamide ribotide transformylase." Analytical Biochemistry90.1(1978):397-401.

Chemical Properties

White to Off-White Solid

Uses

A metabolite of Temozolomide

Uses

4-Aminoimidazole-5-carboxamide is used as Catalytic agent, Petrochemical additive. It is metabolite of temozolomide.

Uses

5-Amino-4-imidazolecarboxamide may be used in the synthesis of 4-(N′-benzoylcarbamoyl)amino-5-imidazolecarboxamide and 5-amino-1-β-D-ribosyl-4-imidazolecarboxamide-5′-phosphate (AICAR).

Definition

ChEBI: An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4.

5-Amino-4-imidazolecarboxamide Preparation Products And Raw materials

Raw materials

Glycinamide

Preparation Products

Temozolomide

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5-Amino-4-imidazolecarboxamide Suppliers

Belgium 1 Canada 2 China 327 Europe 2 France 2 Germany 5 India 15 Japan 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 2 Ukraine 1 United Kingdom 16 United States 41 Global 419

Hefei HomeSunshine Pharmaceutical Technology Co., Ltd.

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BeiJing Hwrk Chemicals Limted

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View Lastest Price from 5-Amino-4-imidazolecarboxamide manufacturers

Hangzhou ICH Biofarm Co., Ltd

Product: 5-Amino-4-imidazolecarboxamide(AICA) 360-97-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.9%min
Supply Ability: 5MT
Release date: 2023-06-12

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Amino-4-imidazolecarboxamide 360-97-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Amino-4-imidazolecarboxamide 360-97-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

360-97-4, 5-Amino-4-imidazolecarboxamideRelated Search:

ALTRENOGEST Formamide Glycine Chlorantraniliprole 4-Aminoimidazole Benzamide N,N-Dimethylformamide Betaine 4-diazo-4H-imidazole-5-carboxamide Cyano temozolomide 5-(Amino-1-(N-methyl Carbamoyl) Temozolomide Temozolomideacid 3-Amino-2-(formylamino)-3-iminopropanamide Cyanotemozolomide TeMozoloMide Metabolite - MTIC 1,5-dihydro-4H-imidazo[4,5-d]-1,2,3-triazin-4-one 1,7-DIMETHYLXANTHINE

4-AMINOIMIDAZOLE-5-CARBOXAMIDE

4-amino-5-imidazolecarboxamid

5-amino-1h-imidazole-4-carboxamid

5-Amino-4-glyoxalinecarboxamide

5-amino-imidazole-4-carboxamid

5-amino-4-imidazolecarboxamide

5-AMINOIMIDAZOLE-4-CARBOXAMIDE

5-AMINO-1H-IMIDAZOLE-4-CARBOXAMIDE

4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE

4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE (AICA) 99.0%

5-Aminoimidazole-4-carboxamide,95%

4(or 5)-Amino-5(or 4)-carbamoylimidazole

4-Amino-5-imidazolecarboxamide ,99%

5-aMino-4-iMidazolecarboxaMide, 5-aMinoiMidazole-4-carboxaMide

4-AMino-5-carbaMoyliMidazole

NSC 7784

5-AMinoiMidazole-4-carboxaMide, 97+%

Temozolomide Aminoimidazole Impurity

Imidazole-4-carboxamide, 5-amino-

1H-imidazo[4,5-d][1,2,3]triazin-4(5H)-one

Temozolomide Impurity B

Temozolomideacid Impurity A: 5-Amino-4-imidazolecarboxamide

Dacarbazine Impurity 2(Dacarbazine EP Impurity B)

Temozolomide Impurity 1(EP-A)

aic

aminoimidazolecarboxamide

ba2756

diazol-c

1H-Imidazole-4-carboxamide, 5-amino-

5-amino-4-imidazolylcarboxamide

4-Amino-5-imidazolecarboxamide monohydrate

AICA, 4-Amino-5-carbamoylimidazole,

4-Amino-5-imodazole

5-AMINI-3H-IMIDAZOLE-4-CARBOXAMIDE

4-aminoimidazole-5-carboxamide hydrate

4-Aminoimidzole-5-carboxamide

Dacarbazine impurity B CRS

Temozolamide Impurity C

4(5)-amino-5(4)-formamide imidazole (ack)

Temozolomide Impurity 1（Temozolomide EP Impurity A）

4-Aminoimidazole-5-carboxamide,95%

4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE 360-97-4

Dacarbazine impurity BQ: What is Dacarbazine impurity B Q: What is the CAS Number of Dacarbazine impurity B Q: What is the storage condition of Dacarbazine impurity B Q: What are the applications of Dacarbazine impurity B

Dacarbazine USP Related Compound A

4-amino-5-carboxamide imidazole

inhibit,5 Amino 3H imidazole 4 Carboxamide,Inhibitor,5Amino3Himidazole4Carboxamide,Endogenous Metabolite

5-Amino-4-imidazolecarboxamide(AICA)

4-Aminoimidazol-5-carboxamide

Temozolomide EP Impurity A（Dacarbazine EP Impurity B）

Temozolamide EP Impurity-A

360-97-4

1299-72-9

C4H6N4OH2O

12612

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Imidazoles

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