ChemicalBook > CAS DataBase List > TAPI-0
TAPI-0
- Product Name
- TAPI-0
- CAS No.
- 163958-73-4
- Chemical Name
- TAPI-0
- Synonyms
- TAPI;TAPI-0 >=95% (HPLC);N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-
- CBNumber
- CB34670622
- Molecular Formula
- C24H32N4O5
- Formula Weight
- 456.53
- MOL File
- 163958-73-4.mol
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TAPI-0 Property
- Density
- 1.227±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO
- form
- powder
- pka
- 9.17±0.20(Predicted)
- color
- white to off-white
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Safety
- RIDADR
- UN 2811 6.1 / PGIII
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1292
- Product name
- TAPI-0
- Purity
- ≥95% (HPLC)
- Packaging
- 1MG
- Price
- $351
- Updated
- 2023/06/20
TRC
- Product number
- T731300
- Product name
- TAPI0
- Packaging
- 1mg
- Price
- $270
- Updated
- 2021/12/16
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TAPI-0 Chemical Properties,Usage,Production
Uses
TAPI 0 is a metalloprotease inhibitor, which inhibits the obligate intracellular human pathogen Chalmydia trachomitis.
Biochem/physiol Actions
TAPI-0 is a metalloproteinase inhibitor with selectivity for TACE (TNF-α converting enzyme/ADAM17; IC50 = 100 nM). TAPI-0 also inhibits of collagenase and gelatinase. Although not specific for TACE, TAPI-0 is extensively used to block TACE-mediated TNF-α shedding.
storage
Store at -20°C
TAPI-0 Preparation Products And Raw materials
Raw materials
Preparation Products
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TAPI-0 Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52924
- Advantage
- 58