2-CHLORO-7-NITROQUINOXALINE
- Product Name
- 2-CHLORO-7-NITROQUINOXALINE
- CAS No.
- 55686-94-7
- Chemical Name
- 2-CHLORO-7-NITROQUINOXALINE
- Synonyms
- TIMTEC-BB SBB014258;2-CHLORO-7-NITROQUINOXALINE;Quinoxaline, 2-chloro-7-nitro-;3-methylene-6-(1-methylethyl)-Cyclohexene
- CBNumber
- CB3472815
- Molecular Formula
- C8H4ClN3O2
- Formula Weight
- 209.59
- MOL File
- 55686-94-7.mol
2-CHLORO-7-NITROQUINOXALINE Property
- Melting point:
- 188 °C
- Boiling point:
- 350.5±37.0 °C(Predicted)
- Density
- 1.566±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -3.57±0.30(Predicted)
- Appearance
- Light yellow to brown Solid
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S745170
- Product name
- 2-CHLORO-7-NITROQUINOXALINE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $30.7
- Updated
- 2025/07/31
- Product number
- S745170
- Product name
- 2-CHLORO-7-NITROQUINOXALINE
- Purity
- AldrichCPR
- Packaging
- 10MG
- Price
- $29.8
- Updated
- 2024/03/01
- Product number
- C385605
- Product name
- 2-Chloro-7-nitroquinoxaline
- Packaging
- 500mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- W6958
- Product name
- 2-Chloro-7-nitroquinoxaline
- Packaging
- 250mg
- Price
- $131
- Updated
- 2021/12/16
- Product number
- 066789
- Product name
- 2-Chloro-7-nitroquinoxaline
- Purity
- >95%
- Packaging
- 500mg
- Price
- $522
- Updated
- 2021/12/16
2-CHLORO-7-NITROQUINOXALINE Chemical Properties,Usage,Production
Synthesis
89898-96-4
55686-94-7
The general procedure for the synthesis of 2-chloro-7-nitroquinoxaline from 7-nitro-2(1H)-quinoxalinone was as follows: in a round-bottomed flask, 7-nitroquinoxalin-2-ol (12.73 g, 67 mmol) was dissolved in 20 mL of phosphorochloridic acid (POCl3), and the mixture was heated and refluxed for 3 hours. Upon completion of the reaction, the reaction mixture was quenched by slowly pouring it into a stirred ice-water mixture. Subsequently, the precipitate was collected by filtration and washed with cold water to give 13.43 g of red to cherry colored solid product in 96% yield. The melting point of the product was 183-186 °C (literature value: 185-189 °C). Analyzed by ATR/FTIR spectroscopy, the main absorption peaks were located at 3092, 3048, 1682, 1525, 1350 and 740 cm?1. 1H NMR (200 MHz, DMSO-d6) δ: 9.22 (s, 1H, H3), 8.88 (d, 1H, J = 3.0 Hz, H8), 8.59 (dd, 1H, J = 2.0 , 9.0 Hz, H6), 8.39 (d, 1H, J = 9.0 Hz, H5).13C NMR (100 MHz, DMSO-d6) δ: 149.2, 148.8, 148.3, 142.8, 140.2, 130.9, 124.1, 123.9.DEPT-135 (100 MHz, DMSO-d6) δ : 148.8, 130.9, 124.1, 123.9. mass spectrometry analysis showed molecular ion peaks of 209.1 and 211.1.
References
[1] Journal of the Brazilian Chemical Society, 2017, vol. 28, # 10, p. 1874 - 1878
[2] Tetrahedron Letters, 1991, vol. 32, # 10, p. 1311 - 1314
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 13, p. 6169 - 6186
[4] Journal of Medicinal Chemistry, 2011, vol. 54, # 13, p. 4508 - 4522
2-CHLORO-7-NITROQUINOXALINE Preparation Products And Raw materials
Raw materials
Preparation Products
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