4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
- Product Name
- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
- CAS No.
- 698-29-3
- Chemical Name
- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
- Synonyms
- NSC 459;Pynitrile;BUTTPARK 27\08-63;5-Cyano-4-aMino-2-MethylpyriMidine;4-AMINO-5-CYANO-2-METHYLPYRIMIDINE;2-methyl-4-amino-5-cyanopyrimidine;2-methyl-4-aminopyrimidine-5-nitrile;4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE;2-Methyl-4-aminopyrimidine-5-carbonitrile;5-Pyrimidinecarbonitrile, 4-amino-2-methyl-
- CBNumber
- CB3477966
- Molecular Formula
- C6H6N4
- Formula Weight
- 134.14
- MOL File
- 698-29-3.mol
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE Property
- Melting point:
- 249 °C
- Boiling point:
- 315.6±27.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO, Ethanol, Methanol
- pka
- 3.00±0.10(Predicted)
- form
- Powder
- color
- Pale yellow
- Water Solubility
- Slightly soluble in water (6.4 g/L at 25°C). Soluble in dimethyl sulfoxide, ethanol and methanol.
- InChI
- InChI=1S/C6H6N4/c1-4-9-3-5(2-7)6(8)10-4/h3H,1H3,(H2,8,9,10)
- InChIKey
- YBPNIILOUYAGIF-UHFFFAOYSA-N
- SMILES
- C1(C)=NC=C(C#N)C(N)=N1
- CAS DataBase Reference
- 698-29-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- WGK Germany
- WGK 1
- Hazard Note
- Irritant
- HazardClass
- 6.1
- HS Code
- 2933599590
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A603517
- Product name
- 4-Amino-5-cyano-2-methylpyrimidine
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- A1376-65
- Product name
- 4-Amino-5-cyano-2-methylpyrimidine
- Packaging
- 1g
- Price
- $375
- Updated
- 2021/12/16
- Product number
- FA17626
- Product name
- 4-Amino-5-cyano-2-methylpyrimidine
- Packaging
- 10g
- Price
- $660.7
- Updated
- 2021/12/16
- Product number
- 064187
- Product name
- 4-Amino-2-methylpyrimidine-5-carbonitrile
- Packaging
- 5g
- Price
- $235
- Updated
- 2021/12/16
- Product number
- J54567
- Product name
- 4-Amino-2-methylpyrimidine-5-carbonitrile
- Packaging
- 10g
- Price
- $320
- Updated
- 2021/12/16
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE Chemical Properties,Usage,Production
Chemical Properties
Pale-Yellow Crystalline Solid
Uses
4-Amino-5-cyano-2-methylpyrimidine is used as a pharmaceutical intermediate.
Synthesis
To a clean 20L reaction flask, add 5kg of water, 5kg of ethanol and mix well. Take solid sodium hydroxide 1.8kg, add to the system and stir for 30min. until completely dissolved. Cool down the ice bath to below 25 degrees Celsius, add 3.2kg of acetamidine hydrochloride, basically no exothermic, white turbid liquid. After adding, stirring for 10min. dropwise addition of ethanol solution of dicyanoacetate, dropwise initial exothermic, insulation below 30 degrees Celsius, the back of the basic non-exothermic, can accelerate the acceleration of the drop. Dropping finished, warming to 65-70 ?? reaction 1.5h. reaction solution while hot slowly poured into 10kg of ice water, stirring for 20min. treatment of liquid centrifuge centrifugation, get 4.6kg of wet product. 70-75 ?? blast drying, to constant weight. Obtained white solid 3.6kg, liquid phase 98.2%, yield 85.7%.
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE Suppliers
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View Lastest Price from 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE manufacturers
- Product
- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE 698-29-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-07-06
- Product
- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE 698-29-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-10
- Product
- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE 698-29-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97-99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-18