Ethoxymethylenemalononitrile

Product Name: Ethoxymethylenemalononitrile
CAS No.: 123-06-8
Chemical Name: Ethoxymethylenemalononitrile
Synonyms: 2-(ETHOXYMETHYLENE)MALONONITRILE;2-(Ethoxymethylene)propanedinitrile;ononitriL;ETHOXYMETHYLENEMALONITRILE;(Ethoxymethylene)propanedinitrile;usafkf-10;NSC 27792;USAF KF-10;usafa-9230;USAF a-9230
CBNumber: CB9767407
Molecular Formula: C6H6N2O
Formula Weight: 122.12
MOL File: 123-06-8.mol

More

Less

Ethoxymethylenemalononitrile Property

Melting point:: 64-66 °C(lit.)
Boiling point:: 160 °C12 mm Hg(lit.)
Density: 1.2236 (rough estimate)
refractive index: 1.4738 (estimate)
Flash point:: 155 °C
storage temp.: Inert atmosphere,Room Temperature
solubility: DMF, DMSO, Ethanol, Methanol
form: Liquid
color: Clear colorless to yellow
Water Solubility: insoluble
BRN: 1634241
InChIKey: OEICGMPRFOJHKO-UHFFFAOYSA-N
CAS DataBase Reference: 123-06-8(CAS DataBase Reference)
NIST Chemistry Reference: Propanedinitrile, (ethoxymethylene)-(123-06-8)
EPA Substance Registry System: Propanedinitrile, (ethoxymethylene)- (123-06-8)

More

Less

Safety

Hazard Codes: Xn,T,Xi
Risk Statements: 22-42/43-23/24/25-43-20/21/22-R42/43-R23/24/25-R22
Safety Statements: 22-36/37-45-36/37/39-26-36-24/25-S45-S36/37/39-S26-S22
RIDADR: 3439
WGK Germany: 3
RTECS: OO3850000
F: 21
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29269090
Toxicity: mouse,LD50,intraperitoneal,50mg/kg (50mg/kg),National Technical Information Service. Vol. AD277-689,

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E6200
Product name: (Ethoxymethylene)malononitrile
Purity: 98%
Packaging: 100g
Price: $32.84
Updated: 2024/03/01

Sigma-Aldrich

Product number: E6200
Product name: (Ethoxymethylene)malononitrile
Purity: 98%
Packaging: 25g
Price: $37.8
Updated: 2024/03/01

TCI Chemical

Product number: E0649
Product name: (Ethoxymethylene)malononitrile
Purity: >98.0%(GC)
Packaging: 25g
Price: $74
Updated: 2024/03/01

Alfa Aesar

Product number: A14412
Product name: Ethoxymethylenemalononitrile, 97+%
Packaging: 25g
Price: $45.65
Updated: 2024/03/01

Alfa Aesar

Product number: A14412
Product name: Ethoxymethylenemalononitrile, 97+%
Packaging: 100g
Price: $99.65
Updated: 2024/03/01

More

Less

Ethoxymethylenemalononitrile Chemical Properties,Usage,Production

Description

Ethoxymethylenemalononitrile (EMMN) is an orange solid and the melting point of EMMN is 64–66 °C[1].It is an inexpensive reagent. As a functionalized malono-nitrile, it is widely used to synthesize pyrazoles, pyrimidines and a variety of fused heterocyclic systems.

Chemical Properties

Off White to Pale Yellow

Uses

Chemical intermediate.

Uses

Ethoxymethylene Malononitrile (cas# 123-06-8) is a compound useful in organic synthesis.

Preparation

Triethyl orthoformate (67.3 mg, 0.454 mol) and malononitrile (20.0 mg,0.302 mol) were andded to acetic anhydride (77.2 gm, 0.75 moles) and the mixture was refluxed for 4-5 h at 110-140°C. The reaction was monitored by GC. After the reaction is complete, it is cooled to room temperature. Concentrated the mixture at 70°C at reduced pressure to yield crude solid product and the pure product (Ethoxymethylenemalononitrile) was obtained through purified either by vacuum distillation.

Synthesis Reference(s)

Tetrahedron Letters, 10, p. 3279, 1969 DOI: 10.1017/S0009838800024678

References

[1] Faria J, et al. Ethoxymethylenemalononitrile. Synlett , 2013; 24: 0264–0265.
[2] Maurício , et al. Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives. Bioorganic & Medicinal Chemistry Letters, 2011; 21: 7451-7454.

Ethoxymethylenemalononitrile Preparation Products And Raw materials

Raw materials

Preparation Products

[4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]METHANOL 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE 4-AMINO-2-MERCAPTOPYRIMIDINE-5-CARBONITRILE 4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBALDEHYDE 4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONITRILE 4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLIC ACID 4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE 4-AMINO-2-CHLOROPYRIMIDINE-5-CARBONITRILE 4-AMINO-2-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID 5-(AMINOMETHYL)-2-(TRIFLUOROMETHYL)PYRIMIDIN-4-AMINE

More

Less

Ethoxymethylenemalononitrile Suppliers

Americas 1 Australia 1 Belgium 3 Canada 2 China 251 Czech Republic 1 Europe 6 Germany 6 India 27 Japan 4 Russia 1 Slovakia 1 South Korea 1 Spain 1 Switzerland 3 The Netherlands 2 United Kingdom 21 United States 61 Global 393

Shanghai Mixiu Chemical Co., Ltd.

Tel: 18101936766
Fax: 021-58583907
Email: eileen@shmychem.com
Country: China
ProdList: 350
Advantage: 55

Tianjin Scaxchem Limited Compnay

Tel: 022-022-25327698 18920479040
Email: sales@cosychem.com
Country: China
ProdList: 589
Advantage: 55

Suzhou Lakestar Pharmatech Co., Ltd.

Tel: 0512-63970158-603 18018108880
Fax: 0512-63971078
Email: info@lakestarpharma.com
Country: China
ProdList: 414
Advantage: 59

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Bridge Organics

Tel: +1269-649-4200
Fax: +1269-649-0611
Email: ab@bridgeorganics.com
Country: United States
ProdList: 162
Advantage: 55

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

More

Less

View Lastest Price from Ethoxymethylenemalononitrile manufacturers

Xinxiang Hongqi District Houyuan Trading Co.,Ltd

Product: Ethoxymethylenemalononitrile 123-06-8
Price: US $0.00/Kg
Min. Order: 1Kg
Purity: 99.0% up
Supply Ability: 50 tons per month
Release date: 2023-04-26

Honest Joy Holdings Limited

Product: (Ethoxymethylene)malononitrile 123-06-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 100 tons
Release date: 2022-02-20

Zhuozhou Wenxi import and Export Co., Ltd

Product: Ethoxymethylenemalononitrile 123-06-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

123-06-8, EthoxymethylenemalononitrileRelated Search:

Diethyl methylmalonate Ethoxyquin 2-Methylpropanedioic acid CITRATE SYNTHASE 2,2-DIMETHYL-1,3-PROPANEDIAMINE Tosylmethyl isocyanide Malononitrile Ethyl 3-ethoxypropionate Diethyl ethoxymethylenemalonate ETHOXYLATED COCOAMINE (LATEX STABILIZER) Ethylamine hydrochloride 2-Methoxyethyl acetoacetate Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-(1-oxo-2-propenyl)oxy-, ether with 2,2-bis(hydroxymethyl)-1,3-propanediol (4:1) Ethoxyamine hydrochloride CHLOROMETHYLDIMETHYLETHOXYSILANE 1,1,2-TRIETHOXYETHANE Ethoxyacetic acid Acetoxyacetyl chloride

ETHOXYMETHYLENEMALONITRILE

ETHOXYMETHYLENEMALONONITRILE

ETHOXYMETHYLENMALONONITRILE

(beta-Ethoxymethylene)malononitrile

(b-Ethoxymethylene)malononitrile

(ethoxymethylene)-malononitril

(ethoxymethylene)-propanedinitril

(Ethoxymethylene)propanedinitrile

1,1-Dicyano-2-ethoxyethene

1-Ethoxy-2,2-dicyanoethene

2-Cyano-3-ethoxyacrylonitrile

2-Ethoxy-1,1-ethenedicarbonitrile

a-Cyano-b-ethoxyacrylonitrile

alpha-Cyano-beta-ethoxyacrylonitrile

Ethoxymethylene-malonic acid dinitrile

Malononitrile, (ethoxymethylene)-

USAF a-9230

USAF KF-10

usafa-9230

LABOTEST-BB LT01148236

2-(ETHOXYMETHYLIDENE)MALONONITRILE

2-(ETHOXYMETHYLENE)MALONONITRILE

PROPANEDINITRILE, (ETHOXYMETHYLENE)-

usafkf-10

ETHOXY METHYLENE MALONOITRILE-

Ethoxy methlenemalononitrile

1-Ethoxy-2,2-dicyanoethylene

Ethoxymethylenemalononitrile ,98%

2-(Ethoxymethylene)propanedinitrile

Ethoxymethylenemalononiyrile

ononitriL

NSC 27792

α-Cyano-β-ethoxyacrylonitrile

Propanedinitrile, 2-(ethoxyMethylene)-

Ethoxy heartland of Methyl Malononitrile

(Ethoxymethylene)malononitrile&gt

Ethoxy malononitrile

Ethoxymethylenmalononitril

2-(Ethoxymethylene)propanedinitrile (or) 2-(ethoxymethylene)malononitrile

ethoxymethylmalonitrile

2-(ethoxymethylene)malonitrile

123-06-8

C6H6N20

C2H5OCHCCN2

Organic Building Blocks

Nitrogen Compounds

Cyanides/Nitriles

Building Blocks

C6 to C7

Aliphatic Compound

Miscellaneous

API intermediates

Various Intermediates

Intermediates

C6 to C7

Cyanides/Nitriles

Nitrogen Compounds

Pharmaceutical Intermediates