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TRIS(DIMETHYLAMINO)METHANE

Product Name
TRIS(DIMETHYLAMINO)METHANE
CAS No.
5762-56-1
Chemical Name
TRIS(DIMETHYLAMINO)METHANE
Synonyms
TRIS(DIMETHYLAMINO)METHANE;Tris(dimethylamino)methane,85%;Tris(N,N-dimethylamino)methane;Tris(dimethylamino)methane 97%;Tris(dimethylamino) methane, 96%+;Tris(diMethylaMino)Methane, 85% 5GR;N,N,N,N,N,N-HEXAMETHYLMETHANETRIAMINE;N,N',N''-Methylidynetris(dimethylamine);N,N,N',N',N'',N''-HEXAMETHYLMETHANETRIAMINE;Methanetriamine, N,N,N',N',N'',N''-hexamethyl-
CBNumber
CB3478150
Molecular Formula
C7H19N3
Formula Weight
145.25
MOL File
5762-56-1.mol
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TRIS(DIMETHYLAMINO)METHANE Property

Boiling point:
42-43 °C/12 mmHg (lit.)
Density 
0.838 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.436(lit.)
Flash point:
4 °F
storage temp. 
2-8°C
form 
Liquid
pka
6.50±0.38(Predicted)
color 
Clear colorless to slightly yellow
BRN 
1901162
InChI
InChI=1S/C7H19N3/c1-8(2)7(9(3)4)10(5)6/h7H,1-6H3
InChIKey
MUMVIYLVHVCYGI-UHFFFAOYSA-N
SMILES
C(N(C)C)(N(C)C)N(C)C
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Safety

Hazard Codes 
F,C
Risk Statements 
11-34
Safety Statements 
16-26-36/37/39-45
RIDADR 
UN 2733 3/PG 2
WGK Germany 
3
3-8-10-21
Hazard Note 
Corrosive/Highly Flammable
HazardClass 
3.1
PackingGroup 
II
HS Code 
29212900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
221058
Product name
Tris(dimethylamino)methane
Purity
97%
Packaging
5g
Price
$266
Updated
2023/01/07
Sigma-Aldrich
Product number
221058
Product name
Tris(dimethylamino)methane
Purity
97%
Packaging
25g
Price
$890
Updated
2023/01/07
TCI Chemical
Product number
T1057
Product name
Tris(dimethylamino)methane
Purity
>97.0%(T)
Packaging
5mL
Price
$253
Updated
2025/07/31
TCI Chemical
Product number
T1057
Product name
Tris(dimethylamino)methane
Purity
>97.0%(T)
Packaging
25mL
Price
$867
Updated
2025/07/31
TRC
Product number
H296930
Product name
N,N,N'',N'',N'''',N''''-Hexamethylmethanetriamine
Packaging
1g
Price
$135
Updated
2021/12/16
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TRIS(DIMETHYLAMINO)METHANE Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

Reagent for the introduction of the dimethylaminoethylidene group.1 General review;2 RO polymerization of lactide.3

Uses

N,N,N'',N'',N'''',N''''-Hexamethylmethanetriamine, can be used in the synthesis of the phosphoramidite derivative of the new nucleoside analog. It can also be used as reagent for the introduction of the dimethylaminoethylidene group.

Uses

Tris(dimethylamino)methane was used:

  • to prepare the phosphoramidite derivative of the new nucleoside analog
  • as reagent for the introduction of the dimethylaminoethylidene group
  • in ring-opening (RO) polymerization of lactide

General Description

NMR spectra and their temperature-dependence has been reported for tris(dimethylamino)methane. Tris(dimethylamino)methane reacts with crowded α-(o-nitrophenyl) ketone to yield tetrahydroquinoline derivative.

Purification Methods

Dry it over KOH and distil it through a Vigreux column (p 11) at water pump vacuum. Store it in the absence of CO2. [Bredereck et al. Chem Ber 101 1885 1968 and Angew Chem, Int Ed Engl 5 132 1966.]

TRIS(DIMETHYLAMINO)METHANE Preparation Products And Raw materials

Raw materials

Preparation Products

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5762-56-1, TRIS(DIMETHYLAMINO)METHANERelated Search:


  • N,N,N',N',N'',N''-HEXAMETHYLMETHANETRIAMINE
  • N,N,N,N,N,N-HEXAMETHYLMETHANETRIAMINE
  • TRIS(DIMETHYLAMINO)METHANE
  • N,N',N''-Methylidynetris(dimethylamine)
  • Tris(dimethylamino)methane,85%
  • N,N,N',N',N'',N''-Hexamethylmethanetriamine 90%
  • Tris(diMethylaMino)Methane, 85% 5GR
  • Tris(N,N-dimethylamino)methane
  • Tris(dimethylamino)methane (stabilized with KOH)
  • Methanetriamine, N,N,N',N',N'',N''-hexamethyl-
  • Tris(dimethylamino) methane, 96%+
  • Tris(dimethylamino)methane 97%
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