ChemicalBook > CAS DataBase List > DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE

DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE

Product Name
DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE
CAS No.
534615-50-4
Chemical Name
DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE
Synonyms
Dec-RVRK-CMK;DECANOYL-ARG-VAL-ARG-LYS-CMK;DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE;L-Argininamide, N2-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-
CBNumber
CB3491450
Molecular Formula
C34H66ClN11O5
Formula Weight
744.41
MOL File
Mol file
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DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE Property

storage temp. 
-15°C
Sequence
{DEC}-Arg-Val-Arg-Lys-{CMK}
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FD111052
Product name
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Packaging
500ug
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD111052
Product name
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Packaging
1mg
Price
$264
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD111052
Product name
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Packaging
2mg
Price
$459
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0011715
Product name
DEC-RVRK-CMK
Purity
95.00%
Packaging
5MG
Price
$496.16
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD111052
Product name
Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Packaging
5mg
Price
$918
Updated
2021/12/16
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DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE Chemical Properties,Usage,Production

Uses

DEC-RVRK-CMK (Decanoyl-Arg-Val-Arg-Lys-chloromethylketone) is a peptide-based CMK (chloromethylketone) inhibitor that targets and inactivates the secreted soluble kexin (Kex2) (Ki=8.45 μM). The yeast enzyme Kex2 (kexin, EC 3.4.21.61) is a calcium-dependent transmembrane protease and belongs to the mammalian protease family of the serine protease subtilisin family. The binding mechanism of Kex2 with different CMK inhibitors depends on substrate selectivity, particularly the selective differences between lysine and arginine at the P1 position[1].

References

[1] Wheatley JL, et al. Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6626-31. DOI:10.1073/pnas.0701983104

DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

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DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE Suppliers

China 26 United Kingdom 1 United States 2 Global 29
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

534615-50-4, DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONERelated Search:


  • DECANOYL-ARG-VAL-ARG-LYS-CHLOROMETHYLKETONE
  • DECANOYL-ARG-VAL-ARG-LYS-CMK
  • Dec-RVRK-CMK
  • L-Argininamide, N2-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-
  • 534615-50-4