4-BROMO-2-METHOXYBENZYL ALCOHOL 97
- Product Name
- 4-BROMO-2-METHOXYBENZYL ALCOHOL 97
- CAS No.
- 17102-63-5
- Chemical Name
- 4-BROMO-2-METHOXYBENZYL ALCOHOL 97
- Synonyms
- (4-Bromo-2-methoxyphenyl);(4-broMo-2-Methoxyphenyl)Methanol;4-Bromo-2-methoxybenzyl alcohol 97%;4-BROMO-2-METHOXYBENZYL ALCOHOL 97;Benzenemethanol, 4-bromo-2-methoxy-;4-Bromo-2-methoxybenzyl alcohol≥ 99% (GC);4-
Bromo- 2- methoxybenzyl alcohol - CBNumber
- CB3498893
- Molecular Formula
- C8H9BrO2
- Formula Weight
- 217.06
- MOL File
- 17102-63-5.mol
4-BROMO-2-METHOXYBENZYL ALCOHOL 97 Property
- Melting point:
- 66-70 °C (lit.)
- Boiling point:
- 291℃
- Density
- 1.513
- Flash point:
- 130℃
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 14.04±0.10(Predicted)
- Appearance
- White to off-white Solid
- Water Solubility
- Insoluble in water.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 653187
- Product name
- 4-Bromo-2-methoxybenzyl alcohol
- Purity
- 97%
- Packaging
- 10g
- Price
- $121.6
- Updated
- 2025/07/31
- Product number
- 653187
- Product name
- 4-Bromo-2-methoxybenzyl alcohol
- Purity
- 97%
- Packaging
- 1g
- Price
- $29.9
- Updated
- 2023/06/20
- Product number
- B696623
- Product name
- 4-Bromo-2-methoxybenzyl alcohol
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B696623
- Product name
- 4-Bromo-2-methoxybenzyl alcohol
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- JK620238
- Product name
- 4-Bromo-2-methoxybenzyl alcohol
- Purity
- 98%
- Packaging
- 1g
- Price
- $44
- Updated
- 2021/12/16
4-BROMO-2-METHOXYBENZYL ALCOHOL 97 Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow fine crystalline powder
Uses
It is used in azaquinone-methide-mediated depolymerization of aromatic carbamate oligomers.
Synthesis
139102-34-4
17102-63-5
General procedure for the synthesis of 4-bromo-2-methoxybenzenemethanol from methyl 4-bromo-2-methoxybenzoate: To a solution of methyl 4-bromo-2-methoxybenzoate (7.14 g, 29 mmol) in tetrahydrofuran (THF, 35 mL) was slowly added a THF solution of 2 M lithium borohydride (LiBH4) (35 mL, 70 mmol, 2.4 equiv). The reaction mixture was heated to reflux at 60 °C for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was evaporated under reduced pressure. The residue was dissolved in 5% aqueous acetic acid (pH adjusted to 6) and stirred for 15 minutes. Subsequently, the aqueous layer was extracted with ethyl acetate (EtOAc, 2 x 50 mL), the organic phases were combined and washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated to give the crude product as a tan oil. The crude product was purified by fast column chromatography using 5% ethyl acetate in hexane solution as eluent to give 5.96 g (94% yield) of the target product 4-bromo-2-methoxybenzenemethanol as a white solid: Thin Layer Chromatography (TLC) Rf value 0.30 (10% ethyl acetate/hexane); 1H NMR (CDCl3) δ 7.30 (d, 1H), 7.14 (d, 1H), 7.11 (d, 1H). 1H), 7.11 (s, 1H), 5.09 (t, 1H), 4.42 (d, 2H), 3.77 (s, 3H).
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 1, p. 419 - 434
[2] Journal of Medicinal Chemistry, 1992, vol. 35, # 4, p. 734 - 740
[3] Patent: WO2006/60461, 2006, A1. Location in patent: Page/Page column 197
[4] ChemMedChem, 2010, vol. 5, # 1, p. 65 - 78
[5] Patent: WO2012/66335, 2012, A1. Location in patent: Page/Page column 54
4-BROMO-2-METHOXYBENZYL ALCOHOL 97 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMO-2-METHOXYBENZYL ALCOHOL 97 manufacturers
- Product
- 4-BROMO-2-METHOXYBENZYL ALCOHOL 17102-63-5
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02