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(R)-(+)-AMINOGLUTETHIMIDE 97

Product Name
(R)-(+)-AMINOGLUTETHIMIDE 97
CAS No.
55511-44-9
Chemical Name
(R)-(+)-AMINOGLUTETHIMIDE 97
Synonyms
CGS-2396;Aminoglutethimide, D-;(R)-(+)-AMINOGLUTETHIMIDE 97;(R)-(+)-Aminoglutethimide 97%;(R)-(+)-Aminoglutethimide;(R)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione;(R)-3-(4-aMinophenyl)-3-ethylpiperidine-2,6-dione;(3R)-3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione;2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-, (3R)-
CBNumber
CB3499719
Molecular Formula
C13H16N2O2
Formula Weight
232.28
MOL File
55511-44-9.mol
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(R)-(+)-AMINOGLUTETHIMIDE 97 Property

Melting point:
115.5-119.5 °C (lit.)
Boiling point:
457.4±45.0 °C(Predicted)
Density 
1.173±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Solid
pka
11.60±0.40(Predicted)
color 
Off-white to light yellow
optical activity
[α]20/D +160°, c = 1 in methanol
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
545872
Product name
(R)-(+)-Aminoglutethimide
Purity
97%
Packaging
500mg
Price
$196.88
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
API0009817
Product name
(R)-(+)-AMINOGLUTETHIMIDE
Purity
97.00%
Packaging
5MG
Price
$499.72
Updated
2021/12/16
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(R)-(+)-AMINOGLUTETHIMIDE 97 Chemical Properties,Usage,Production

Uses

(R)-(+)-Aminoglutethimide can be used:

  • As a building block for the development of cephalosporin based prodrug for antibody-directed enzyme prodrug therapy (ADEPT).
  • To prepare (R)-3-ethyl-3-(4-(3,4,5-trimethoxybenzylamino)phenyl)piperidine-2,6-dione by reacting with 3,4,5-trimethoxybenzylamine via deaminative coupling reaction.
  • To synthesize (R)-2-fluoro-2-(4-methoxyphenyl)-N-(R)-(+)-aminoglutethimide by enantioselective α-fluorination.

Definition

ChEBI: The (3R)-enantiomer of aminoglutethimide.

in vivo

(R)-(+)-Aminoglutethimide (5, 50 mg/kg; p.o.) eliminates within 48 hr into urine and feces, mostly in the form of metabolites[2].
(R)-(+)-Aminoglutethimide (1, 10, 50 mg/kg; i.p.; 60 min before training) dose not induce any significant effect in 1 and 10 mg/kg, induces a loss of retention at 50 mg/kg in day-old chicks[3].

IC 50

Aromatase

(R)-(+)-AMINOGLUTETHIMIDE 97 Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-AMINOGLUTETHIMIDE 97 Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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57
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
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80
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
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58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Fax
025 86918232
Email
sales_china@pharmablock.com
Country
China
ProdList
10000
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
sales@pharmablock.com
Country
China
ProdList
7268
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58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
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58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
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58
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323658 +86-18168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39002
Advantage
58

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