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METHYL 4-FLUOROPHENYLACETATE

Product Name
METHYL 4-FLUOROPHENYLACETATE
CAS No.
34837-84-8
Chemical Name
METHYL 4-FLUOROPHENYLACETATE
Synonyms
Methyl 2-(4-fluorophenyl);METHYL 4-FLUOROPHENYLACETATE;Methyl4-fluorophenylacetate,98%;METHYL 4-FLUOROPHENYLACETATE, 99;Methyl 4-fluorophenylacetate 98%;Methyl 2-(4-fluorophenyl)acetate;Benzeneacetic acid, 4-fluoro-, methyl ester
CBNumber
CB3502055
Molecular Formula
C9H9FO2
Formula Weight
168.16
MOL File
34837-84-8.mol
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METHYL 4-FLUOROPHENYLACETATE Property

Boiling point:
210°C (rough estimate)
Density 
1.1410 (estimate)
refractive index 
1.4870
storage temp. 
Sealed in dry,Room Temperature
form 
Liquid
color 
Clear colorless to yellow
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Safety

Risk Statements 
36/37/38
Safety Statements 
36/37/39-26
HS Code 
29153900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M305558
Product name
Methyl2-(4-fluorophenyl)acetate
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
119944
Product name
Methyl 2-(4-fluorophenyl)acetate
Purity
95+%
Packaging
1g
Price
$28
Updated
2021/12/16
SynQuest Laboratories
Product number
2623-3-X0
Product name
Methyl 4-fluorophenylacetate
Purity
98%
Packaging
250mg
Price
$35
Updated
2021/12/16
SynQuest Laboratories
Product number
2623-3-X0
Product name
Methyl 4-fluorophenylacetate
Purity
98%
Packaging
1g
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-W008065
Product name
Methyl2-(4-fluorophenyl)acetate
Packaging
25g
Price
$65
Updated
2021/12/16
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METHYL 4-FLUOROPHENYLACETATE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Synthesis

67-56-1

405-50-5

34837-84-8

Step 1: 4-Fluorophenylacetic acid (700 mg, 4.34 mmol) was dissolved in methanol at room temperature and concentrated sulfuric acid (0.42 mL, 4.34 mmol, 0.1 equiv) was added slowly. The reaction mixture was refluxed under nitrogen protection at 70 °C for 3 h. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm complete consumption of the feedstock. After completion of the reaction, the mixture was cooled to room temperature. The solvent was evaporated under reduced pressure and the residue was extracted with ethyl acetate. The organic phase was washed sequentially with saturated brine and dried over anhydrous magnesium sulfate. The organic phase was concentrated under reduced pressure to give the crude product. Finally, the crude product was purified by column chromatography to afford methyl 2-(4-fluorophenyl)acetate (660 mg, 84% yield).

References

[1] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2843 - 2866
[2] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 15, p. 4694 - 4703
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 3, p. 1151 - 1156
[4] Patent: WO2005/14539, 2005, A2. Location in patent: Page/Page column 57-59; 68-69
[5] Tetrahedron, 2002, vol. 58, # 51, p. 10113 - 10126

METHYL 4-FLUOROPHENYLACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 4-FLUOROPHENYLACETATE Suppliers

Belgium 1 China 87 Germany 1 India 3 United Kingdom 2 United States 12 Global 106
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from METHYL 4-FLUOROPHENYLACETATE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
METHYL 4-FLUOROPHENYLACETATE 34837-84-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-31
Career Henan Chemical Co
Product
METHYL 4-FLUOROPHENYLACETATE, 99 34837-84-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99.99%
Supply Ability
200KG
Release date
2019-09-03

34837-84-8, METHYL 4-FLUOROPHENYLACETATERelated Search:

Methyl 4-Chloronicotinate METHYL 4-METHYLPHENYLACETATE METHYL 4-FLUOROPHENYLACETATE METHYL 2-CHLORO-4-FLUOROPHENYLACETATE 98 3-(3,4-Difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone METHYL 2,3,4,5,6-PENTAFLUOROPHENYLACETATE ETHYL 3,4-DIFLUOROBENZOYLFORMATE METHYL 3,4-DIFLUOROBENZOYLFORMATE 2-Pentafluorophenyl-malonic acid diethyl ester ETHYL 4-FLUOROBENZOYLFORMATE ETHYL 4-FLUORO-3-METHYLBENZOYLFORMATE ETHYL 3,4,5-TRIFLUOROBENZOYLFORMATE BROMO-(4-FLUORO-PHENYL)-ACETIC ACID ETHYL ESTER METHYL 2-(4-FLUOROPHENYL)-4-(3-METHOXYPHENYL)-4-OXOBUTANOATE RARECHEM AK ML 0194 METHYL 4-(4-CHLOROPHENYL)-2-(4-FLUOROPHENYL)-4-OXOBUTANOATE SPECS AN-698/41114311 SPECS AN-698/41114315

  • Methyl 2-(4-fluorophenyl)acetate
  • Methyl 4-fluorophenylacetate 98%
  • Methyl 2-(4-fluorophenyl)
  • METHYL 4-FLUOROPHENYLACETATE, 99
  • Benzeneacetic acid, 4-fluoro-, methyl ester
  • METHYL 4-FLUOROPHENYLACETATE
  • Methyl4-fluorophenylacetate,98%
  • 34837-84-8