CHRYSOMYCIN B
- Product Name
- CHRYSOMYCIN B
- CAS No.
- 83852-56-6
- Chemical Name
- CHRYSOMYCIN B
- Synonyms
- B,ChrysoMycin;CHRYSOMYCIN B USP/EP/BP;ChrysoMycin M, VirenoMycin M, Albacarcin M;6H-Benzo[d]naphtho[1,2-b]pyran-6-one, 4-(6-deoxy-3-C-methyl-β-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-;4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one;6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl- (9CI)
- CBNumber
- CB3503294
- Molecular Formula
- C27H28O9
- Formula Weight
- 496.51
- MOL File
- 83852-56-6.mol
CHRYSOMYCIN B Property
- Boiling point:
- 784.0±60.0 °C(Predicted)
- Density
- 1.410
- storage temp.
- 2-8°C
- solubility
- DMF: soluble
- form
- solid
- pka
- 8.59±0.20(Predicted)
- color
- Yellow to greenish
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P337+P313IF eye irritation persists: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C6491
- Product name
- Chrysomycin B
- Purity
- ≥98%(HPLC),solid
- Packaging
- 100μg
- Price
- $305
- Updated
- 2022/05/15
- Product number
- 14189
- Product name
- Chrysomycin B
- Purity
- ≥98%
- Packaging
- 250μg
- Price
- $166
- Updated
- 2024/03/01
- Product number
- 14189
- Product name
- Chrysomycin B
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $395
- Updated
- 2024/03/01
- Product number
- C433035
- Product name
- Chrysomycin B
- Packaging
- 500μg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- C433035
- Product name
- Chrysomycin B
- Packaging
- 250μg
- Price
- $115
- Updated
- 2021/12/16
CHRYSOMYCIN B Chemical Properties,Usage,Production
Description
Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. It differs from its analog chrysomycin A by having a methyl, rather than vinyl, group in the 8-position of the chromophore. Like its analog, chrysomycin B suppresses the growth of transplantable tumors in mice, an effect that may be related to its ability to bind DNA. It also causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B is structurally very similar to gilvocarcin V, which promotes DNA cross-linking with histone 3 and GRP78 when photoactivated by near-UV light.
Uses
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumour actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumour active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated crosslinkers of DNA to histones.
Uses
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumor active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated cross-linkers of DNA to histones.
Uses
Chrysomycin B is an inhibitor of the catalytic activity of human topoisomerase II.
storage
+4°C
CHRYSOMYCIN B Preparation Products And Raw materials
Raw materials
Preparation Products
CHRYSOMYCIN B Suppliers
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- 020-39119399 18927568969
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- 020-39119999
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- China
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- 021-52907766-8042
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- 021-52906523
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- 86-(0)29-85992781 17792393971
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- United States
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View Lastest Price from CHRYSOMYCIN B manufacturers
- Product
- CHRYSOMYCIN B 83852-56-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-19
- Product
- Chrysomycin B 83852-56-6
- Price
- US $0.01-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-05-12
- Product
- CHRYSOMYCIN B 83852-56-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-03-11