ChemicalBook > CAS DataBase List > 1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98

1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98

Product Name
1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98
CAS No.
73889-19-7
Chemical Name
1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98
Synonyms
N-benzyl-4-BOC aminopiperidine;4-Boc-aMino-1-benzylpiperidine;N-Benzyl-4-(N-Boc-aMino)piperidine;1-Benzyl-4-(N-Boc-amino)piperidine;4-(N-Boc-aMino)-1-benzyl-piperidine;1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98;1-Benzyl-4-(N-Boc-amino) piperidine, 95%;tert-Butyl 1-benzylpiperidin-4-ylcarbamate;tert-butyl N-(1-benzylpiperidin-4-yl)carbamate;1-Benzyl-4-(tert-butoxycarbonylamino)piperidine
CBNumber
CB3504680
Molecular Formula
C17H26N2O2
Formula Weight
290.4
MOL File
73889-19-7.mol
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1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98 Property

Melting point:
122-125 °C(lit.)
Boiling point:
400.9±34.0 °C(Predicted)
Density 
1.07±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.35±0.20(Predicted)
Appearance
White to off-white Solid
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B130135
Product name
1-Benzyl-4-(N-Boc-amino)piperidine
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
B130135
Product name
1-Benzyl-4-(N-Boc-amino)piperidine
Packaging
50mg
Price
$60
Updated
2021/12/16
TRC
Product number
B130135
Product name
1-Benzyl-4-(N-Boc-amino)piperidine
Packaging
100mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-864
Product name
1-Benzyl-4-(Boc-amino)piperidine
Packaging
25g
Price
$263
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0015085
Product name
(1-BENZYL-PIPERIDIN-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity
95.00%
Packaging
25G
Price
$1291.58
Updated
2021/12/16
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1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98 Chemical Properties,Usage,Production

Chemical Properties

White powder

Synthesis

50541-93-0

24424-99-5

73889-19-7

General procedure for the synthesis of tert-butyl (1-benzylpiperidin-4-yl)carbamate from 4-amino-1-benzylpiperidine and di-tert-butyl dicarbonate: to an anhydrous solution of 4-amino-1-benzylpiperidine (1 mL, 933 mg, 4.9 mmol) in dichloromethane (20 mL) was added triethylamine (1 mL, 725 mg, 7.2 mmol) and di-tert-butyl dicarbonate ( 1.23 g, 5.6 mmol). The reaction mixture was stirred overnight at room temperature and then diluted with dichloromethane (20 mL). The organic layer was washed sequentially with saturated aqueous sodium bicarbonate (10 mL) and saturated saline (10 mL), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give tert-butyl (1-benzylpiperidin-4-yl)carbamate (1.42 g, quantitative yield) as a white solid.

References

[1] Patent: WO2013/140148, 2013, A1. Location in patent: Page/Page column 65
[2] Journal of Medicinal Chemistry, 1999, vol. 42, # 14, p. 2706 - 2715
[3] Journal of Medicinal Chemistry, 1999, vol. 42, # 24, p. 4981 - 5001
[4] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 24, p. 5345 - 5352
[5] Patent: WO2007/46550, 2007, A1. Location in patent: Page/Page column 117

1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98 Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98 Suppliers

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View Lastest Price from 1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98 manufacturers

Hebei Mingeng Biotechnology Co., Ltd
Product
1-Benzyl-4-(N-Boc-amino)piperidine 73889-19-7
Price
US $150.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
500kg/month
Release date
2022-05-06
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Benzyl-4-(N-Boc-amino) piperidine 73889-19-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Benzyl-4-(N-Boc-amino) piperidine 73889-19-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

73889-19-7, 1-BENZYL-4-(N-BOC-AMINO) PIPERIDINE 98Related Search:


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