6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID

Product Name: 6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID
CAS No.: 5463-29-6
Chemical Name: 6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID
Synonyms: 6-bromo-2-oxo-1H-quinoline-4-carboxylic acid;6-bromo-2-keto-1H-quinoline-4-carboxylic acid;6-Bromo-2-oxo-1,2-dihydroquinoline-5-carboxylic acid;4-Quinolinecarboxylic acid, 6-bromo-1,2-dihydro-2-oxo-
CBNumber: CB3507010
Molecular Formula: C10H6BrNO3
Formula Weight: 268.06
MOL File: 5463-29-6.mol

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6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Property

Boiling point:: 446.7±45.0 °C(Predicted)
Density: 1.804±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2.54±0.20(Predicted)
Appearance: Off-white to light yellow Solid

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Safety

HazardClass: IRRITANT
HS Code: 2933491090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R423203
Product name: 6-BROMO-2-HYDROXY-QUINOLINE-4-CARBOXYLIC ACID
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $113
Updated: 2025/07/31

Sigma-Aldrich

Product number: R423203
Product name: 6-BROMO-2-HYDROXY-QUINOLINE-4-CARBOXYLIC ACID
Purity: AldrichCPR
Packaging: 50MG
Price: $110
Updated: 2024/03/01

Matrix Scientific

Product number: 010461
Product name: 6-Bromo-2-hydroxyquinoline-4-carboxylic acid
Packaging: 1g
Price: $378
Updated: 2021/12/16

Matrix Scientific

Product number: 115070
Product name: 6-Bromo-2-oxo-1,2-dihydroquinoline-4-carboxylic acid
Purity: >97%
Packaging: 500mg
Price: $451
Updated: 2021/12/16

Apolloscientific

Product number: OR310688
Product name: 6-Bromo-2-oxo-1,2-dihydroquinoline-4-carboxylicacid
Packaging: 1g
Price: $520
Updated: 2021/12/16

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6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

541-50-4

87-48-9

5463-29-6

6-Bromo-2-hydroxy-4-carboxylic acid quinoline was synthesized using the method described in Scheme 6. The procedure was as follows: 5-bromoindoline-2,3-dione (0.250 g) was dissolved in tetrahydrofuran (THF, 3 ml) in a round-bottomed flask, followed by the addition of malonic acid (2 equiv). The unit was connected to a reflux condenser and heated to reflux by conventional heating and the reaction was continued overnight. After 12 hours of reaction, a solid precipitate was observed to be generated. Subsequently, the suspension was concentrated under reduced pressure to remove the solvent, and the suspension was refluxed for 4 hours after addition of an appropriate amount of water. Finally, the solid product was collected by filtration to afford 6-bromo-2-hydroxyquinoline-4-carboxylic acid (0.150 g) in solid form.

References

[1] Patent: US2014/221387, 2014, A1. Location in patent: Paragraph 0383; 0384; 0385

6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Suppliers

China 42 Germany 1 India 3 United Kingdom 1 United States 5 Global 52

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5463-29-6, 6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACIDRelated Search:

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5463-29-6