6-BROMO-2(1H)-QUINOLONE
- Product Name
- 6-BROMO-2(1H)-QUINOLONE
- CAS No.
- 1810-66-8
- Chemical Name
- 6-BROMO-2(1H)-QUINOLONE
- Synonyms
- 6-BROMOQUINOLIN-2(1H)-ONE;6-bromoquinolin-2-ol;2-Hydroxy-6-bromoquinoline;P-524;109404;6-Bromocarbostyril;6-BROMO-2-QUINOLONE;6-Bromo-2-quinolinol;6-Bromo-2-quinolinone;6-bromoquinolin-2-one
- CBNumber
- CB9763838
- Molecular Formula
- C9H6BrNO
- Formula Weight
- 224.05
- MOL File
- 1810-66-8.mol
6-BROMO-2(1H)-QUINOLONE Property
- Melting point:
- 278-280?C
- Boiling point:
- 393.8±42.0 °C(Predicted)
- Density
- 1.620±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO
- form
- Solid
- pka
- 10.76±0.70(Predicted)
- color
- Beige
- InChI
- InChI=1S/C9H6BrNO/c10-7-2-3-8-6(5-7)1-4-9(12)11-8/h1-5H,(H,11,12)
- InChIKey
- YLAFBGATSQRSTB-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(Br)C=C2)C=CC1=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BBO000085
- Product name
- 2-Hydroxy-6-bromoquinoline
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $216
- Updated
- 2025/07/31
- Product number
- B686950
- Product name
- 6-Bromo-2(1H)-quinolinone
- Packaging
- 2g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FB19058
- Product name
- 6-Bromo-2(1H)-quinolinone
- Packaging
- 10g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- FB19058
- Product name
- 6-Bromo-2(1H)-quinolinone
- Packaging
- 2g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB19058
- Product name
- 6-Bromo-2(1H)-quinolinone
- Packaging
- 5G
- Price
- $120
- Updated
- 2021/12/16
6-BROMO-2(1H)-QUINOLONE Chemical Properties,Usage,Production
Chemical Properties
Beige Solid
Uses
6-Bromo-2(1H)-quinolinone is a useful intermediate for the synthesis of other quinoline derivatives.
Synthesis
327058-51-5
1810-66-8
General procedure for the synthesis of 6-bromoquinolin-2(1H)-one from the compound (CAS:327058-51-5): 6-bromo-2(1H)-quinolinone (6.0 g, 22.2 mmol) was dissolved in concentrated H2SO4 (30 mL) and the reaction was heated in an oil bath at 100 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and quenched with ice water. The precipitate precipitated was collected by filtration, washed with water and subsequently dried under vacuum to afford 6-bromoquinolin-2(1H)-one as a white solid (4.8 g, 97% yield). Mass spectrum (ES+) m/e 225 [M+H]+.
References
[1] Patent: WO2006/132739, 2006, A2. Location in patent: Page/Page column 35-36
[2] Chemical and Pharmaceutical Bulletin, 2014, vol. 62, # 6, p. 508 - 518
[3] European Journal of Medicinal Chemistry, 2000, vol. 35, # 10, p. 931 - 940
[4] Journal of Medicinal Chemistry, 2005, vol. 48, # 1, p. 306 - 311
6-BROMO-2(1H)-QUINOLONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-BROMO-2(1H)-QUINOLONE manufacturers
- Product
- 6-BROMO-2(1H)-QUINOLONE 1810-66-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-05
- Product
- 6-Bromo-2(1H)-quinolone;2-Hydroxy-6-bromoquinoline;6-Bromo-2(1H)-quinolinone ada@tuskwei.com 1810-66-8
- Price
- US $3.00/KG
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- 7000g/day ada@tuskwei.com whatsapp;+08617197824028
- Release date
- 2018-01-11
- Product
- 6-Bromo-2(1H)-quinolone 1810-66-8
- Price
- US $2.00/G
- Min. Order
- 1G
- Purity
- 99.5% lila@tuskwei.com sky:lila_1646 whatsapp:+8617197824208
- Supply Ability
- 500kg per week
- Release date
- 2018-02-01