6-bromoquinoxalin-2(1H)-one
Uses- Product Name
- 6-bromoquinoxalin-2(1H)-one
- CAS No.
- 55687-34-8
- Chemical Name
- 6-bromoquinoxalin-2(1H)-one
- Synonyms
- 6-BROMOQUINOXALIN-2-OL;6-bromo-1H-quinoxalin-2-one;6-bromoquinoxalin-2(1H)-one;6-Bromo-2-hydroxyquinoxaline;2(1H)-Quinoxalinone, 6-broMo-;6-broMo-1,2-dihydroquinoxalin-2-one;4,6-DIMETHYLCYCLOHEXYLAMINEHYDROCHLORIDE
- CBNumber
- CB01515826
- Molecular Formula
- C8H5BrN2O
- Formula Weight
- 225.04
- MOL File
- 55687-34-8.mol
6-bromoquinoxalin-2(1H)-one Property
- Melting point:
- 298-300 °C(Solv: acetic acid (64-19-7))
- Density
- 1.82±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 8.10±0.70(Predicted)
- Appearance
- Light brown to gray Solid
- InChI
- InChI=1S/C8H5BrN2O/c9-5-1-2-6-7(3-5)10-4-8(12)11-6/h1-4H,(H,11,12)
- InChIKey
- BDBWPIXISLYKEG-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(Br)C=C2)N=CC1=O
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B696273
- Product name
- 6-Bromo-2-hydroxyquinoxaline
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB42254
- Product name
- 6-Bromo-2-hydroxyquinoxaline
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB42254
- Product name
- 6-Bromo-2-hydroxyquinoxaline
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FB42254
- Product name
- 6-Bromo-2-hydroxyquinoxaline
- Packaging
- 1g
- Price
- $210
- Updated
- 2021/12/16
- Product number
- 073234
- Product name
- 6-Bromo-2-hydroxyquinoxaline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $260
- Updated
- 2021/12/16
6-bromoquinoxalin-2(1H)-one Chemical Properties,Usage,Production
Uses
6-Bromoquinoxaline-2(1H)-one is a quinoline derivative that can be used as a pharmaceutical intermediate.
Synthesis
96089-46-2
55687-34-8
Part B. Synthesis of 6-bromoquinoxalin-2(1H)-one: To a solution of sodium hydroxide (337 mg, 8.4 mmol) in water (2.1 mL) was added the product of Part A (423 mg, 1.4 mmol) and the reaction was stirred for 1 hr at 65°C. The reaction was completed with the addition of sodium borohydride (31.9 mg, 0.84 mmol). Upon completion of the reaction, the solution was cooled to room temperature, diluted with water (4 mL), followed by the addition of sodium borohydride (31.9 mg, 0.84 mmol), and continued to be stirred at room temperature for 1.5 hours. Ice was added to the reaction mixture and 6 μL of hydrochloric acid was added slowly and dropwise until the solution became acidic. The precipitated solid product was collected by filtration, washed with water and dried in a vacuum oven to afford 6-bromoquinoxalin-2(1H)-one (273 mg, 86% yield).
References
[1] Patent: WO2009/39134, 2009, A1. Location in patent: Page/Page column 185
[2] Heterocycles, 1985, vol. 23, # 1, p. 143 - 151
6-bromoquinoxalin-2(1H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-bromoquinoxalin-2(1H)-one manufacturers
- Product
- 6-bromoquinoxalin-2(1H)-one 55687-34-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-11