ChemicalBook > CAS DataBase List > (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

Product Name
(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride
CAS No.
88046-01-9
Chemical Name
(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride
Synonyms
N-[4-[[(amino iminomethyl) thio]-methyl]-2-thiazolyl]-guanidine dihydrochloride (FMT-II);Famotidine Impurity 13;Iso Thiourea Hcl. (ITU);Famotidine Impurity H DiHCl;Famotidine EP Impurity H HCL;Famotidine Related Compound h;Famotidine EP Impurity H DiHCl;Famotidine Isothiourea Impurity;[2-[(Diaminomethylidene)amino]thiaz;Famotidine EP Impurity H Dihydrochloride
CBNumber
CB3511561
Molecular Formula
C6H11ClN6S2
Formula Weight
266.77
MOL File
88046-01-9.mol
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(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Property

Melting point:
>188oC (dec.)
storage temp. 
Refrigerator
solubility 
DMSO (Sparingly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
PH
3.89 at 1000g/L
InChI
InChI=1S/C6H10N6S2.ClH/c7-4(8)12-6-11-3(2-14-6)1-13-5(9)10;/h2H,1H2,(H3,9,10)(H4,7,8,11,12);1H
InChIKey
DMXJVYCDETXZRR-UHFFFAOYSA-N
SMILES
N(C1SC=C(CSC(N)=N)N=1)C(N)=N.Cl
LogP
1 at 30℃ and pH3.89
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H332Harmful if inhaled

H402Harmful to aquatic life

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
G835800
Product name
S-(2-Guanidino-4-thiazolyl)methylisothioureaDihydrochloride
Packaging
10g
Price
$1070
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0003021
Product name
(S)-((2-GUANIDINO-4-THIAZOLYL)METHYLISOTHIOUREA DIHYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$269.85
Updated
2021/12/16
AK Scientific
Product number
R863
Product name
S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea2HCl
Packaging
1g
Price
$276
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0003021
Product name
(S)-((2-GUANIDINO-4-THIAZOLYL)METHYLISOTHIOUREA DIHYDROCHLORIDE
Purity
95.00%
Packaging
10G
Price
$2055.9
Updated
2021/12/16
aablocks
Product number
AA00GR64
Product name
(S)-((2-Guanidino-4-thiazolyl)methylisothioureadihydrochloride
Packaging
25g
Price
$125
Updated
2021/12/16
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(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Chemical Properties,Usage,Production

Uses

Famotidine intermediate.

Definition

Famotidine EP Impurity H is chemically (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride. It is also known as Famotidine Isothiourea Impurity . Famotidine EP Impurity H can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Famotidine.

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Preparation Products And Raw materials

Raw materials

Amidinothiourea 1,3-Dichloroacetone

Preparation Products

3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER
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(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Suppliers

Canada 2 China 133 Germany 1 India 14 Singapore 1 United Kingdom 2 United States 6 Global 159
Molekula Ltd
Tel
--
Fax
--
Email
info@molekula.com
Country
United Kingdom
ProdList
4060
Advantage
50
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
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View Lastest Price from (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride manufacturers

Guangzhou PI PI BIOTECH INC
Product
Famotidine EP Impurity H 88046-01-9
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2021-08-17
Hebei Zhanyao Biotechnology Co. Ltd
Product
(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 88046-01-9
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-23
Qiuxian Baitai New Material Co., LTD
Product
(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 88046-01-9
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
500ton/Month
Release date
2021-12-21

88046-01-9, (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochlorideRelated Search:

N-DesaMinosulfonyl-N-cyano FaMotidine Famotidine EP Impurity A [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) Acetonitrile Benzothiazole Methanol Methyl acrylate Methylparaben Tetramethylthiourea Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) N-Aminothiourea Glycine 2-Methyl-4-isothiazolin-3-one Sulfamide FAMOTIDINE RELATED COMPOUND B 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide Bis[(2-guanidino-4-thiazolyl)methyl]disulfide

  • Famotidine EP Impurity H DiHCl
  • Famotidine Impurity H DiHCl
  • N-[4-[[(amino iminomethyl) thio]-methyl]-2-thiazolyl]-guanidine dihydrochloride (FMT-II)
  • Carbamimidothioic acid [2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl ester dihydrochloride
  • N-(4-(((AMINOIMINOMETHYL)THIO)METHYL)-2-THIAZOLYL)GUANIDINE
  • S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea 2HCl
  • S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea dihydrochloride
  • N-[4-(Aminoiminomethyl)Thiomethyl-2-Thiazolyl]Guanidine Dihydrochloride
  • N"-[4-(Aminoiminomethyl)thiomethyl-2-thiazolyl]guanidine2HCl
  • Carbamimidothioic acid(2-aminoiminomethyl)amino)-4-Thiazolyl)methyl ester
  • (2-((diaminomethylene)amino)thiazol-4-yl)methyl carbamimidothioate diHCl
  • Carbamimidothioic Acid [2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl Ester DiHCl
  • S-(2-Guanidino-4-thiazolyl)methylisothiour
  • Famotidine EP Impurity H Dihydrochloride
  • Famotidine Impurity 13
  • Famotidine Isothiourea Impurity
  • [2-[(Diaminomethylidene)amino]thiaz
  • Famotidine Related Compound h
  • (2-guanidinothiazol-4-yl)methyl carbamimidothioate dihydrochloride
  • amino(methylsulfanyl)methaniminium chloride
  • (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochlor...
  • (2-Guanidinothiazol-4-yl)methyl carbamimidothioate dihydrochloride (Famotidine Impurity)
  • Famotidine Impurity 13 (Famotidine EP Impurity H Dihydrochloride)
  • Iso Thiourea Hcl. (ITU)
  • Famotidine Impurity H as Dihydrochloride
  • Famotidine EP Impurity H as Dihydrochloride
  • ISO THIOUREA [(S)-((2-GUANIDINO-4-THIAZOLYL) METHYLISOTHIOUREA DIHYDROCHLORIDE](ITU)
  • ((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride
  • S-[(2-Guanidino-4-thiazolyl)] isothiourea dihydrochloride
  • Famotidine EP Impurity H HCL
  • (2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride
  • 88046-01-9
  • C6H12Cl2N6S2
  • C6H10N6S22HCl
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds