VP3.15 Dihydrobromide
- Product Name
- VP3.15 Dihydrobromide
- CAS No.
- 1281681-33-1
- Chemical Name
- VP3.15 Dihydrobromide
- Synonyms
- VP3.15 Dihydrobromide;VP3.15 dihydrobromide, 10 mM in DMSO;N-(2-Morpholinoethyl)-2,3-diphenyl-1,2,4-thiadiazol-5(2H)-imine dihydrobromide;Glycogen synthase kinase-3,VP3.15 dihydrobromide,inhibit,Inhibitor,VP-3.15 dihydrobromide,Glycogen synthase kinase 3,GSK-3,Phosphodiesterase (PDE)
- CBNumber
- CB35441036
- Molecular Formula
- C20H23BrN4OS
- Formula Weight
- 447.4
- MOL File
- 1281681-33-1.mol
VP3.15 Dihydrobromide Property
- storage temp.
- Store at -20°C
- solubility
- dmso:62.5(Max Conc. mg/mL);118.3(Max Conc. mM)
- form
- Solid
- color
- Light yellow to yellow
N-Bromosuccinimide Price
- Product number
- CS-0101863
- Product name
- VP3.15(dihydrobromide)
- Purity
- 98.22%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-0101863
- Product name
- VP3.15(dihydrobromide)
- Purity
- 98.22%
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- CS-0101863
- Product name
- VP3.15(dihydrobromide)
- Purity
- 98.22%
- Packaging
- 50mg
- Price
- $900
- Updated
- 2021/12/16
- Product number
- CS-0101863
- Product name
- VP3.15(dihydrobromide)
- Purity
- 98.22%
- Packaging
- 100mg
- Price
- $1550
- Updated
- 2021/12/16
- Product number
- 027577
- Product name
- VP3.15dihydrobromide
- Packaging
- 003
- Price
- $2200
- Updated
- 2021/12/16
VP3.15 Dihydrobromide Chemical Properties,Usage,Production
Description
VP3.15 Dihydrobromide is a novel dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor.
Uses
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS)[1].
target
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
References
[1] Medina-Rodríguez EM, et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis. Sci Rep. 2017 Mar 3;7:43545. DOI:10.1038/srep43545
VP3.15 Dihydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
VP3.15 Dihydrobromide Suppliers
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