Cardiotoxin Analog (CTX) IV 6-12

Product Name: Cardiotoxin Analog (CTX) IV 6-12
CAS No.: 115722-23-1
Chemical Name: Cardiotoxin Analog (CTX) IV 6-12
Synonyms: Cardiotoxin Analog;L-Lysinamide, L-leucyl-L-isoleucyl-L-prolyl-L-prolyl-L-phenylalanyl-L-tryptophyl- (9CI)
CBNumber: CB35475664
Molecular Formula: C48H70N10O7
Formula Weight: 899.13
MOL File: 115722-23-1.mol

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Cardiotoxin Analog (CTX) IV 6-12 Property

Boiling point:: 1240.9±65.0 °C(Predicted)
Density: 1.236±0.06 g/cm3(Predicted)
form: Solid
pka: 13.45±0.20(Predicted)
color: White to off-white
Sequence: H-Leu-Ile-Pro-Pro-Phe-Trp-Lys-NH2

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Hazard and Precautionary Statements (GHS)

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Cardiotoxin Analog (CTX) IV 6-12 Chemical Properties,Usage,Production

Uses

Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol). Cardiotoxin Analog (CTX) IV (6-12) binds to cell membranes through hydrophobic interactions and electrostatic attraction. Cardiotoxin Analog (CTX) IV (6-12) is mainly embedded in the lipid bilayer through the N-terminal hydrophobic loop (amino acid sequence at positions 6-12), destroying the stability of the membrane structure, inducing membrane lipid disorder and cell lysis, and exhibiting hemolysis and cytotoxicity[1][2].

References

[1] Kaneda N, et al. The amino acid sequence of cardiotoxin-analogue IV from the venom of Naja naja atra. FEBS Lett. 1976 Nov;70(1):217-22. DOI:10.1016/0014-5793(76)80761-2
[2] Dufourcq J, et al. Structure-function relationships for cardiotoxins interacting with phospholipids. Toxicon. 1982;20(1):165-74. DOI:10.1016/0041-0101(82)90187-8

Cardiotoxin Analog (CTX) IV 6-12 Preparation Products And Raw materials

Raw materials

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Cardiotoxin Analog (CTX) IV 6-12 Suppliers

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115722-23-1, Cardiotoxin Analog (CTX) IV 6-12Related Search:

MDL 29,913 SEGLITIDE AC-TRP-NHME cyclo(L-leucyl-L-tryptophyl) DESOTAMIDE

L-Lysinamide, L-leucyl-L-isoleucyl-L-prolyl-L-prolyl-L-phenylalanyl-L-tryptophyl- (9CI)

Cardiotoxin Analog

115722-23-1