Ramatercept

Product Name: Ramatercept
CAS No.: 1169766-01-1
Chemical Name: Ramatercept
Synonyms: RAMATERCEPT;Research Grade Ramatercept;Research Grade Ramatercept (DHA30606);Activin receptor type IIB (synthetic human extracellular domain fragment) fusion protein with glycylglycylglycine fusion protein with immunoglobulin G1 (synthetic human Fc region C-terminal fragment), dimer
CBNumber: CB35554099
Formula Weight: 0
MOL File: Mol file

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Ramatercept Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Ramatercept Chemical Properties,Usage,Production

Description

Ramatercept is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy.

Uses

Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy[1][2][3].

in vivo

Ramatercept (10 mg/kg; s.c.; three times a week for 5 weeks) significantly increases the muscle mass of mice.

References

[1] Fariello R G, et al. A novel Biological (FOX-115) improves endurance of motor performances in old mice (P2. 4-033)[J]. 2019.
[2] Feike Y, et al. Advances in research on pharmacotherapy of sarcopenia. Aging Med (Milton). 2021 Aug 9;4(3):221-233. DOI:10.1002/agm2.12168
[3] Louvel é. Dopage: nouveaux médicaments influant sur la biogenèse musculaire et mitochondriale[J]. 2019.

Ramatercept Preparation Products And Raw materials

Raw materials

Preparation Products

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Ramatercept Suppliers

China 6 Global 6

AFINE CHEMICALS LIMITED

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Nantong Guangyuan Chemicl Co,Ltd

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1169766-01-1, RamaterceptRelated Search:

Activin receptor type IIB (synthetic human extracellular domain fragment) fusion protein with glycylglycylglycine fusion protein with immunoglobulin G1 (synthetic human Fc region C-terminal fragment), dimer

RAMATERCEPT

Research Grade Ramatercept (DHA30606)

Research Grade Ramatercept

1169766-01-1