ChemicalBook > CAS DataBase List > ML401
ML401
- Product Name
- ML401
- CAS No.
- 1597489-14-9
- Chemical Name
- ML401
- Synonyms
- ML401;CID73169083;ML401 ,E0106;ML401 (CID73169083);ML401, 10 mM in DMSO;ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401;(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one;(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-
- CBNumber
- CB35559120
- Molecular Formula
- C20H20BrClN2O
- Formula Weight
- 419.74
- MOL File
- 1597489-14-9.mol
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ML401 Property
- Boiling point:
- 557.2±50.0 °C(Predicted)
- Density
- 1.422±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 10.42 mg/mL (24.82 mM)
- pka
- 5.99±0.10(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0066585
- Product name
- ML401
- Purity
- 99.87%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0066585
- Product name
- ML401
- Purity
- 99.87%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0066585
- Product name
- ML401
- Purity
- 99.87%
- Packaging
- 25mg
- Price
- $990
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0066585
- Product name
- ML401
- Purity
- 99.87%
- Packaging
- 50mg
- Price
- $1650
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0066585
- Product name
- ML401
- Purity
- 99.87%
- Packaging
- 100mg
- Price
- $2250
- Updated
- 2021/12/16
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ML401 Chemical Properties,Usage,Production
Uses
ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1].
in vivo
ML401 shows very good stability in both human plasma and mouse plasma[1].
References
[1] Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet]. PMID:25834900
ML401 Preparation Products And Raw materials
Raw materials
Preparation Products
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ML401 Suppliers
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