ChemicalBook > CAS DataBase List > ML401

ML401

Product Name
ML401
CAS No.
1597489-14-9
Chemical Name
ML401
Synonyms
ML401;CID73169083;ML401 ,E0106;ML401 (CID73169083);ML401, 10 mM in DMSO;ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401;(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one;(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-
CBNumber
CB35559120
Molecular Formula
C20H20BrClN2O
Formula Weight
419.74
MOL File
1597489-14-9.mol
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ML401 Property

Boiling point:
557.2±50.0 °C(Predicted)
Density 
1.422±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 10.42 mg/mL (24.82 mM)
pka
5.99±0.10(Predicted)
form 
Solid
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0066585
Product name
ML401
Purity
99.87%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0066585
Product name
ML401
Purity
99.87%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0066585
Product name
ML401
Purity
99.87%
Packaging
25mg
Price
$990
Updated
2021/12/16
ChemScene
Product number
CS-0066585
Product name
ML401
Purity
99.87%
Packaging
50mg
Price
$1650
Updated
2021/12/16
ChemScene
Product number
CS-0066585
Product name
ML401
Purity
99.87%
Packaging
100mg
Price
$2250
Updated
2021/12/16
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ML401 Chemical Properties,Usage,Production

Uses

ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1].

in vivo

ML401 shows very good stability in both human plasma and mouse plasma[1].

References

[1] Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet]. PMID:25834900

ML401 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML401 Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4769
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55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
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62
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
12475
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58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29760
Advantage
68
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58

1597489-14-9, ML401Related Search:


  • ML401
  • CID73169083
  • 2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-
  • (E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one
  • ML401 (CID73169083)
  • ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401
  • (E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one
  • ML401, 10 mM in DMSO
  • ML401 ,E0106
  • 1597489-14-9
  • C20H20BrClN2O