ML401

Product Name: ML401
CAS No.: 1597489-14-9
Chemical Name: ML401
Synonyms: ML401;CID73169083;ML401 ，E0106;ML401 (CID73169083);ML401, 10 mM in DMSO;ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401;(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one;(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-
CBNumber: CB35559120
Molecular Formula: C20H20BrClN2O
Formula Weight: 419.74
MOL File: 1597489-14-9.mol

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ML401 Property

Boiling point:: 557.2±50.0 °C(Predicted)
Density: 1.422±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 10.42 mg/mL (24.82 mM)
pka: 5.99±0.10(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 25mg
Price: $990
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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ML401 Chemical Properties,Usage,Production

Uses

ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1].

in vivo

ML401 shows very good stability in both human plasma and mouse plasma^[1].

References

[1] Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet]. PMID:25834900

ML401 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML401 Suppliers

China 32 United States 3 Global 35

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
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ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 7999
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Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
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Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29661
Advantage: 68

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
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InvivoChem

Tel: +1-708-310-1919 +1-13798911105
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
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1597489-14-9, ML401Related Search:

ML401

CID73169083

2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-

(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one

ML401 (CID73169083)

ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401

(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one

ML401, 10 mM in DMSO

ML401 ，E0106

1597489-14-9

C20H20BrClN2O