BAK1 antibody
Applications Immunogen Background- Product Name
- BAK1 antibody
- Chemical Name
- BAK1 antibody
- Synonyms
- BAK1 antibody;Mouse Monoclonal BAK1 Antibody
- CBNumber
- CB35607261
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb18359
- Product name
- BAK1 antibody
- Purity
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Packaging
- 20μg(Trial Size)
- Price
- $127.5
- Updated
- 2021/12/16
- Product number
- orb18359
- Product name
- BAK1 antibody
- Purity
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Packaging
- 100μg
- Price
- $499.8
- Updated
- 2021/12/16
BAK1 antibody Chemical Properties,Usage,Production
Applications
BAK1 antibody has been tested by ELISA, Western blot and Immunofluorescence analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:250 ~ 500.
Recommended starting dilution is 1:
Immunogen
Anti-human BAK1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BAK1 amino acids 29-187 purified from E. coli.
Background
BAK1 is a member of the BCL2 protein family. The BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators which are involved in a wide variety of cellular activities. The BAK1 gene encodes a receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtamembrane domain, and a kinase domain. BAK1 localizes to mitochondria, and functions to induce apoptosis. BAK1 interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to a loss in membrane potential and the release of cytochrome c. Furthermore, BAK1 interacts with the tumor suppressor P53 after exposure to cell stress. BAK1 expression is linked to the progression of Prostate cancer.
BAK1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
BAK1 antibody Suppliers
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