(1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol

Product Name: (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol
CAS No.: 22972-51-6
Chemical Name: (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol
Synonyms: (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol;trans-Mentha-2,8-dien-1-ol;(1S,4R) 1-METHYL-4-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-OL;cis-Isolimonenol;8-DIEN-1-OL;4R)-P-MENTHA-2;CanbidiolImpurity2;Cinchocaine Monomer;Cannabidiol Impurity 2;(+) p-mentha-2,8-dien-1-ol
CBNumber: CB3670819
Molecular Formula: C10H16O
Formula Weight: 152.23
MOL File: 22972-51-6.mol

More

Less

(1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol Property

Boiling point:: 69-70 °C(Press: 3 Torr)
Density: 0.9398
Flash point:: 87.0±19.6 °C
storage temp.: 2-8°C
solubility: Chloroform (Soluble), Methanol (Soluble)
pka: 14.66±0.40(Predicted)
form: Oil
color: Colourless
optical activity: -0.11° (C=1.00 g/100ml, CHCL3)
Water Solubility: 4.2g/L
Stability:: Light Sensitive
InChI: InChI=1S/C10H16O/c1-8(2)9-4-6-10(3,11)7-5-9/h4,6,9,11H,1,5,7H2,2-3H3/t9-,10+/m0/s1
InChIKey: MKPMHJQMNACGDI-VHSXEESVSA-N
SMILES: [C@@]1(C)(O)CC[C@@H](C(C)=C)C=C1
LogP: 2.82

More

Less

Safety

HS Code: 2906190090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TRC

Product number: M320460
Product name: (1S,4R)-1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol
Packaging: 500mg
Price: $460
Updated: 2021/12/16

Matrix Scientific

Product number: 084692
Product name: (1S,4R)-4-Isopropenyl-1-methylcyclohex-2-en-1-ol
Purity: 97%
Packaging: 100g
Price: $965
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 52301
Product name: 1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol
Packaging: 1g
Price: $1075
Updated: 2021/12/16

AK Scientific

Product number: J95374
Product name: (1S,4R)-p-Mentha-2,8-dien-1-ol
Packaging: 100g
Price: $1350
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 52301
Product name: 1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol
Packaging: 2.5g
Price: $2250
Updated: 2021/12/16

More

Less

(1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol Chemical Properties,Usage,Production

Uses

1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol is an acetal reagent used in the synthesis of desoxy cannabidiols and THC (T293202) related psychoactive compounds. It is formed from (+)-Limonene using a photosynthesized O2 transfer.

Definition

ChEBI: (1S,4R)-p-Mentha-2,8-dien-1-ol is a p-menthane monoterpenoid.

Synthesis

1415961-21-5

22972-51-6

The 1S,2S,5R-N,N,2-trimethyl-2-hydroxy-5-isopropenylcyclohexylamine oxide (1.430 g, 6.7 mmol) was heated in a Kugelrohr oven at 180 °C under 1 mmHg vacuum until the solid residue completely disappeared. The yellow distillate (1.317 g) was collected and purified by fast chromatography (ether:hexane=2:3) to afford the target product (1S,4R)-1-methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol (0.752 g, 74% yield) as a colorless oil. the Rf value was 0.32 (ether:hexane=2:3); the specific optical rotation [α]D26: +60 (c=1.0, CHCl3), consistent with literature value [α]D23: +53.8 (CHCl3); IR spectrum (SeZn) showed absorption peaks: 3354 (medium, broad, O-H), 2967 (medium, C-H), 2935 (medium, CH), 2861 (medium, CH), 1644 (medium, C=C), 1105 (strong, CO), and 888 (strong, C=CH bent), 736 (strong, C=CH bent) cm-1; 1H NMR (500 MHz, CDCl3) chemical shift: δ 5.70 (1H, ddd, 3JH2-H3=10.0 Hz, 4JH2-H4=2.4 Hz, 4JH2-H6=1.4 Hz, H2), 5.65 (1H, ddd. 3JH3-H2=10.0 Hz, 3JH3-H4=2.4 Hz, 4JH3-H5=0.8 Hz, H3), 4.78 (1H, quin, 4JH9b-H10≈4JH9b-H4=1.6 Hz, H9b), 4.74 (1H, quin, 4JH9a-H10≈4JH9a-H4=0.88 Hz, H9a), 2.65 (1H, m, H4), 1.88-1.73 (2H, m, H5eq, H6eq), 1.73 (3H, s, H10), 1.66-1.51 (3H, m, H5ax, H6ax, OH), 1.29 (3H, s, H7) ppm; 13C NMR (125 MHz, CDCl3) chemical shift : 148.3 (C8), 134.1 (C2), 132.3 (C3), 110.7 (C9), 67.6 (C1), 43.6 (C4), 36.9 (C6), 29.6 (C7), 25.0 (C5), 21.0 (C10) ppm; low resolution mass spectra (GC-MS): m/z 152 (M+, 2%), 134 ( [M-H2O]+, 11%), 119 ([M-CH3-H2O]+, 32%), 91 (100%), 79 (37%), 77 (46%); Elemental analysis (C10H16O) Calculated values: C 78.90, H 10.59; Measured values: C 78.25, H 10.59, N < 0.05.

References

[1] Tetrahedron Letters, 2013, vol. 54, # 1, p. 52 - 54

(1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol Suppliers

Canada 1 China 233 India 4 United Kingdom 2 United States 12 Global 252

Suzhou Hosyn Pharm Ltd.

Tel: 17621975170; 17621975170
Email: sales@hosynpharm.com
Country: China
ProdList: 492
Advantage: 58

Xishi Chemical (Shanghai) Co., Ltd.

Tel: 021-60499358 13661956116
Fax: +86 (21) 5106-9359
Email: info@cs-pharm.com
Country: China
ProdList: 223
Advantage: 58

Jinan Cen Ben Medical Technology Co., Ltd

Tel: 14793566
Email: info@cenpharm.com
Country: China
ProdList: 773
Advantage: 58

Taizhou Blazer Biomedical Technology Co., Ltd.

Tel: 0523-86112008 13915404123
Fax: 0523-86112008
Email: sales@blazerbio.com
Country: China
ProdList: 274
Advantage: 58

BEIJING EAGLE SKY PHARMATECH CO., LTD

Tel: 010-88755821 13911359480
Email: sophia_818@126.com
Country: China
ProdList: 294
Advantage: 55

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Suzhou Jinglige Technology Co., Ltd

Tel: 18551175068
Email: jinglige888@163.com
Country: China
ProdList: 249
Advantage: 58

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 023-13650506873 19923294409
Email: xingcanyaoye@sina.com
Country: China
ProdList: 1604
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

More

Less

View Lastest Price from (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol manufacturers

Xi an Biohorlden Industry Trade Co Ltd

Product: cis-Isolimonenol 22972-51-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 200 kg
Release date: 2025-06-09

Guangzhou Tengyue Chemical Co., Ltd.

Product: (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol 22972-51-6
Price: US $2300.00-1500.00/kg
Min. Order: 1kg
Purity: 99% Purity (What/sapp: +86 18145728414)
Supply Ability: 1000 Tons/Month
Release date: 2023-06-30

Zhengzhou Anbu Chem Co.,Ltd

Product: (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol 22972-51-6
Price: US $0.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2023-06-13

22972-51-6, (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enolRelated Search:

trans-4-Aminocyclohexanemethanol N,N-DIETHYLBENZAMIDE 2-Methylindole Adenosine 3-METHYLSTYRENE VINYL PROPIONATE Methoxyethene (1R)-(+)-TRANS-ISOLIMONENE (4R)-1-METHYL-4-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-OL (1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol

(1S,4R) 1-METHYL-4-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-OL

(+)-(1S,4R)-P-MENTHA-2,8-DIEN-1-OL

2-Cyclohexen-1-ol,1-Methyl-4-(1-Methylethenyl)-, (1S,4R)-

(1S,4R)-1-methyl-4-prop-1-en-2-ylcyclohex-2-en-1-ol

(1S,4R)-p-Menth-2,8-dien-1-ol

(1S,4S)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-en-1-ol

(1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-en-1-ol22972-51-6

(1S,4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-2-enol

trans-Mentha-2,8-dien-1-ol

(1S,4R)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-2-eno

(1S,4R)-4-Isopropenyl-1-methylcyclohex-2-en-1-ol

(1S,4R)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-2-en-1-ol 97+%

(1S,4R)-1-Methyl-4-(1-propen-2-yl)-2-cyclohexenol

cis-Isolimonenol

(+)-(1S,4R)-P-MENTHA-2,8-DIEN-1-OL ISO 9001：2015 REACH

4R)-P-MENTHA-2

8-DIEN-1-OL

(+) p-mentha-2,8-dien-1-ol

CanbidiolImpurity2

Benzenemethanol,α-(aminomethyl)-7-bromo-

Milbemycin oxime 129496-10-2

2-Cyclohexen-1-ol,1-methyl-4-(1-methylethenyl)-, (1S,4R)- (Menthadienol)

Cannabidiol Impurity 2

Cinchocaine Monomer

(1S,4R)-1 methyl-4-(prop-1 -en-2-yl)cylclohex-2-enol

(+)-cis-p-Mentha-2,8-dien-1-ol

(1S,4R)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-2-en-1-ol/cis-Isolimonenol

Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol

(+)-(1S,4R)-p-Mentha-2,8-dien-1-ol -

1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol

22972-51-6