trans-4-Aminocyclohexanemethanol
- Product Name
- trans-4-Aminocyclohexanemethanol
- CAS No.
- 1467-84-1
- Chemical Name
- trans-4-Aminocyclohexanemethanol
- Synonyms
- ((1R,4r)-4-aMinocyclohexyl)Methanol;(trans-4-Aminocyclohexyl)methanol;Aminocyclohexanemethanol;trans-4-Aminocyclohexanemethanol;Cyclohexanemethanol, 4-amino-, trans-;Rel-((1r,4r)-4-aminocyclohexyl)methanol;trans-1-Amino-4-(hydroxymethyl)cyclohexane
- CBNumber
- CB01565164
- Molecular Formula
- C7H15NO
- Formula Weight
- 129.2
- MOL File
- 1467-84-1.mol
trans-4-Aminocyclohexanemethanol Property
- Melting point:
- 146-148?C
- Boiling point:
- 218.8±13.0 °C(Predicted)
- Density
- 0.974±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Chloroform, Dichloromethane, Methanol
- form
- Solid
- pka
- 15.05±0.10(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C7H15NO/c8-7-3-1-6(5-9)2-4-7/h6-7,9H,1-5,8H2/t6-,7-
- InChIKey
- GHUJZOFJZVGTSN-LJGSYFOKSA-N
- SMILES
- [C@@H]1(CO)CC[C@@H](N)CC1
- CAS DataBase Reference
- 1467-84-1
Safety
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A603535
- Product name
- trans4-Aminocyclohexanemethanol
- Packaging
- 250mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- 002075
- Product name
- trans 4-Aminocyclohexanemethanol
- Packaging
- 50mg
- Price
- $418
- Updated
- 2021/12/16
- Product number
- 7282AA
- Product name
- (trans-4-Aminocyclohexyl)methanol
- Packaging
- 1g
- Price
- $512
- Updated
- 2021/12/16
- Product number
- 6457
- Product name
- trans-4-Aminocyclohexanemethanol
- Packaging
- 50mg
- Price
- $890
- Updated
- 2021/12/16
- Product number
- CHM0068718
- Product name
- TRANS-4-AMINOCYCLOHEXANEMETHANOL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1085.4
- Updated
- 2021/12/16
trans-4-Aminocyclohexanemethanol Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Metabolites of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (Me CCNU)
Synthesis
1678-68-8
1467-84-1
General procedure for the synthesis of (trans-4-aminocyclohexyl)methanol from ethyl trans-4-aminocyclohexanecarboxylate: 1. a suspension was prepared by suspending ethyl trans-4-aminocyclohexanecarboxylate (Intermediate 16; 7.2 g, 0.034 mol) in THF (200 mL). 2. the above suspension was slowly added to lithium aluminum hydride (69 mL of 1 M THF solution, 0.069 mol) and the reaction system was kept at 0 °C. 3. The reaction mixture was stirred continuously for 1 hour at 0 °C. 4. The ice bath was removed and the reaction mixture was stirred overnight at room temperature. 5. The stirred reaction mixture was placed back in the ice bath to cool and water (6.9 mL), 15% NaOH solution (21 mL) and water (21 mL) were added slowly and carefully in sequence. 6. After continued stirring at room temperature for 30 min, the reaction mixture was filtered through a thin layer of diatomaceous earth (1 cm) and the filter cake was washed with THF. 7. The filtrate was combined with the washings and subjected to evaporation and concentration to afford a white solid product, the title compound (trans-4-aminocyclohexyl) methanol (4.4 g, 99% yield). Product characterization data: 1H NMR (300 MHz, DMSO) δ 3.18 (d, J = 6.3 Hz, 2H), 2.42 (m, 1H), 1.79-1.60 (m, 4H), 1.30-1.13 (m, 1H), 1.05-0.72 (m, 4H).
References
[1] Patent: WO2016/46390, 2016, A1. Location in patent: Page/Page column 44
trans-4-Aminocyclohexanemethanol Preparation Products And Raw materials
Raw materials
Preparation Products
trans-4-Aminocyclohexanemethanol Suppliers
- Tel
- 523-86810021 18921709486
- Fax
- gwli@elitechemie.com
- gwli@elitechemie.com
- Country
- China
- ProdList
- 509
- Advantage
- 65
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15394
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 5000
- Advantage
- 55
- Tel
- 18515581800 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 9400
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
View Lastest Price from trans-4-Aminocyclohexanemethanol manufacturers
- Product
- trans-4-Aminocyclohexanemethanol 1467-84-1
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-24
- Product
- trans-4-Aminocyclohexanemethanol 1467-84-1
- Price
- US $5.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100kg/month
- Release date
- 2020-10-30
- Product
- trans-4-Aminocyclohexanemethanol 1467-84-1
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 99.9%
- Supply Ability
- 20tons
- Release date
- 2020-09-21