N,N-DIETHYLNICOTINAMIDE
- Product Name
- N,N-DIETHYLNICOTINAMIDE
- CAS No.
- 59-26-7
- Chemical Name
- N,N-DIETHYLNICOTINAMIDE
- Synonyms
- NIKETHAMIDE;Nikotin;CORVOTONE;Tonocard;nicor;Ni-Cor;Corivo;Cormed;Cormid;Corvin
- CBNumber
- CB3677171
- Molecular Formula
- C10H14N2O
- Formula Weight
- 178.23
- MOL File
- 59-26-7.mol
N,N-DIETHYLNICOTINAMIDE Property
- Melting point:
- 23 °C (lit.)
- Boiling point:
- 296-300 °C (lit.)
- Density
- 1.06 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.524(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- pka
- pKa 3.46(H2O,t =20) (Uncertain)
- form
- Liquid
- color
- Clear colorless to yellow
- Merck
- 14,6543
- BRN
- 5743
- InChI
- InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3
- InChIKey
- NCYVXEGFNDZQCU-UHFFFAOYSA-N
- SMILES
- C1=NC=CC=C1C(N(CC)CC)=O
- CAS DataBase Reference
- 59-26-7(CAS DataBase Reference)
- EPA Substance Registry System
- Nikethamide (59-26-7)
Safety
- Hazard Codes
- T
- Risk Statements
- 25-36/37/38-23/24/25
- Safety Statements
- 26-45-36/37/39
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- QS4375000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29333999
- Toxicity
- LD50 i.p. in rats: 272 mg/kg (Goldenthal)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- D98807
- Product name
- N,N-Diethylnicotinamide
- Purity
- 99%
- Packaging
- 25g
- Price
- $62.4
- Updated
- 2024/03/01
- Product number
- D98807
- Product name
- N,N-Diethylnicotinamide
- Purity
- 99%
- Packaging
- 100g
- Price
- $128
- Updated
- 2023/06/20
- Product number
- N0800000
- Product name
- Nikethamide
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- n0800000
- Price
- $220
- Updated
- 2024/03/01
- Product number
- D98807
- Product name
- N,N-Diethylnicotinamide
- Purity
- 99%
- Packaging
- 500g
- Price
- $176
- Updated
- 2024/03/01
- Product number
- 459840
- Product name
- N,N-Diethylnicotinamide
- Packaging
- 2.5g
- Price
- $403
- Updated
- 2021/12/16
N,N-DIETHYLNICOTINAMIDE Chemical Properties,Usage,Production
Description
A further Corydalis alkaloid, coramine has been obtained from C. pseudoadunca M. Pop. It forms colourless needles from EtOH and is optically active with a specific rotation of [α]D - 391 ° (c 0.2, MeOH). Both the hydrochloride, m.p. 216-9°C and the hydrobromide, m.p. 223-6°C have been described.
Chemical Properties
clear colorless to yellow liquid
Uses
analeptic
Uses
N,N-Diethylnicotinamide (DENC) is commonly used as a ligand to prepare tetranuclear copper complexes.
Definition
ChEBI: Nikethamide is a pyridinecarboxamide. It is functionally related to a nicotinamide.
Application
N,N-Diethylnicotinamide (DENA) is one of the central respiratory stimulants and is used in the study of respiratory failure. DENA is also an excellent hydrophilic agent for paclitaxel (PTX) and improves the water solubility of PTX.
General Description
Clear light yellow viscous liquid or crystalline solid. Slightly bitter taste followed by a faint sensation of the warmth.
Air & Water Reactions
Water soluble.
Reactivity Profile
N,N-DIETHYLNICOTINAMIDE is incompatible with sodium carbonate solutions which cause precipitation. .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition N,N-DIETHYLNICOTINAMIDE emits toxic fumes.
Fire Hazard
N,N-DIETHYLNICOTINAMIDE is combustible.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.
References
Yunusov, Akramov, Yunusov, Dokl. Akad. Nauk. USSR, 162,607 (1965)
Yunusov, Akramov, Yunusov, Khim. Prir. Soedin., 2, 340 (1966)
Ibragimova, Yunusov, Yunusov, ibid, 6,438 (1970)
Yunusov, et al., ibid, 7, 380 (1971)
N,N-DIETHYLNICOTINAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
N,N-DIETHYLNICOTINAMIDE Suppliers
- Tel
- --
- Fax
- --
- biuro@pol-aura.pl
- Country
- Poland
- ProdList
- 1453
- Advantage
- 58
View Lastest Price from N,N-DIETHYLNICOTINAMIDE manufacturers
- Product
- N,N-DIETHYLNICOTINAMIDE 59-26-7
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 99.0%
- Supply Ability
- 1tons
- Release date
- 2024-04-28
- Product
- N,N-DIETHYLNICOTINAMIDE 59-26-7
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-21
- Product
- Nikethamide 59-26-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 0.98
- Supply Ability
- 1000
- Release date
- 2024-07-19