4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
- Product Name
- 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
- CAS No.
- 65874-27-3
- Chemical Name
- 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
- Synonyms
- tert-butyl 4-forMylbenzoate;4-(tert-Butoxycarbonyl)benzaldehyde;4-Formylbenzoic Acid tert-Butyl Ester;4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER;Benzoic acid, 4-formyl-, 1,1-dimethylethyl ester;4-ForMyl-benzoic acid Mono tert-butyl ester(70%)
- CBNumber
- CB3684128
- Molecular Formula
- C12H14O3
- Formula Weight
- 206.24
- MOL File
- 65874-27-3.mol
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Property
- Melting point:
- 52.0 to 56.0 °C
- Boiling point:
- 310.7±25.0 °C(Predicted)
- Density
- 1.093±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- color
- White to Orange to Green
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B5414
- Product name
- tert-Butyl 4-Formylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $199
- Updated
- 2025/07/31
- Product number
- B5414
- Product name
- tert-Butyl 4-Formylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $492
- Updated
- 2025/07/31
- Product number
- B745425
- Product name
- tert-Butyl 4-Formylbenzoate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 102870
- Product name
- 4-Formyl-benzoic acid mono tert-butyl ester
- Purity
- >95%
- Packaging
- 500mg
- Price
- $544
- Updated
- 2021/12/16
- Product number
- CS-W007267
- Product name
- tert-Butyl 4-Formylbenzoate
- Purity
- >98.0%
- Packaging
- 10g
- Price
- $299
- Updated
- 2021/12/16
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Chemical Properties,Usage,Production
Synthesis
24424-99-5
619-66-9
65874-27-3
Example 1 Synthesis of tert-butyl 4-formylbenzoate: To a 250 mL round bottom flask were sequentially added tert-butyl para-formylbenzoate (5.0 g, 33 mmol), di-tert-butyl dicarbonate (14.54 g, 66.6 mmol), 4-dimethylaminopyridine (0.814 g, 6.66 mmol) and tetrahydrofuran (100 mL). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give the crude product. Ethyl acetate (150 mL) was added to the residue and washed with saturated sodium bicarbonate solution (25 mL) and water (25 mL). After partitioning, the aqueous phase was back-extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, washed with saturated saline (50 mL), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. Finally, it was purified by fast column chromatography (eluent: petroleum ether to 10% ethyl acetate-petroleum ether gradient elution) to give tert-butyl 4-formylbenzoate (1.90 g, 28% yield) as a white solid. The product was characterized by 1H NMR (CDCl3, 400 MHz): δ 10.10 (s, 1H), 8.14 (d, J = 8.3 Hz, 2H), 7.93 (d, J = 8.5 Hz, 2H), 1.61 (s, 9H).
References
[1] Journal of the American Chemical Society,
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 7488 - 7489
[3] Patent: US2003/176495, 2003, A1
[4] Patent: US2011/212969, 2011, A1. Location in patent: Page/Page column 109
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER manufacturers
- Product
- 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER 65874-27-3
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-14