ChemicalBook > CAS DataBase List > L-4-BENZOYLPHENYLALANINE

L-4-BENZOYLPHENYLALANINE

Product Name: L-4-BENZOYLPHENYLALANINE
CAS No.: 104504-45-2
Chemical Name: L-4-BENZOYLPHENYLALANINE
Synonyms: (S)-2-aMino-3-(4-benzoylphenyl)propanoic acid;H-BPA-OH;4-BENZOYL-L-PHENYLALANINE;P-BENZOYL-L-PHENYLALANINE;(2S)-2-aMino-3-(4-benzoylphenyl)propanoic acid;Al660-1;L-Bpa-OH;H-4-Bz-Phe-Oh;H-P-BZ-PHE-OH;H-PHE(P-BZ)-OH
CBNumber: CB3686238
Molecular Formula: C16H15NO3
Formula Weight: 269.3
MOL File: 104504-45-2.mol

Less

L-4-BENZOYLPHENYLALANINE Property

Boiling point:: 467.6±40.0 °C(Predicted)
Density: 1.249±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMF: insol; DMSO: insol; Ethanol: insol; PBS (pH 7.2): insol
form: A solid
pka: 2.16±0.10(Predicted)
color: White to light yellow
InChI: InChI=1S/C16H15NO3/c17-14(16(19)20)10-11-6-8-13(9-7-11)15(18)12-4-2-1-3-5-12/h1-9,14H,10,17H2,(H,19,20)/t14-/m0/s1
InChIKey: TVIDEEHSOPHZBR-AWEZNQCLSA-N
SMILES: C(O)(=O)[C@H](CC1=CC=C(C(=O)C2=CC=CC=C2)C=C1)N

Less

Safety

Safety Statements: 24/25
HS Code: 29225090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

AK Scientific

Product number: O027
Product name: L-p-Benzoylphenylalanine
Packaging: 250mg
Price: $92
Updated: 2021/12/16

Activate Scientific

Product number: AS43582
Product name: (S)-2-Amino-3-(4-benzoylphenyl)propanoic acid
Purity: 95% ee
Packaging: 1g
Price: $98
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48340
Product name: 4-Benzoyl-L-phenylalanine
Packaging: 2g
Price: $120
Updated: 2021/12/16

AK Scientific

Product number: O027
Product name: L-p-Benzoylphenylalanine
Packaging: 1g
Price: $128
Updated: 2021/12/16

Apolloscientific

Product number: BIBA1027
Product name: H-p-Bz-Phe-OH
Packaging: 1g
Price: $129
Updated: 2021/12/16

Less

L-4-BENZOYLPHENYLALANINE Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

4-Benzoyl-L-phenylalanine is a photoreactive amino acid which can easily be incorporated into a peptide by solid-phase synthesis and finds application as phtolabel. It is an important raw material as well as an intermediate in organic synthesis.

Synthesis

63-91-2

98-88-4

104504-45-2

The general procedure for the synthesis of (S)-2-amino-3-(4-benzoylphenyl)propionic acid from L-phenylalanine and benzoyl chloride was as follows: in a reaction tube fitted with a screw cap and polytetrafluoroethylene (PTFE)-faced rubber lining, L-phenylalanine (16.5 mg, 0.1 mmol) was added followed by trifluoromethanesulfonic acid (0.5 mL). After the solution was homogenized, benzoyl chloride (8 eq.) was added slowly at 0 °C. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the mixture was poured into a mixture of cold water and ethyl acetate. The organic layer was separated, washed with saturated sodium chloride solution, dried over anhydrous magnesium sulfate and filtered. The filtrate was concentrated and the residue was purified by silica gel column chromatography (eluent ratio ethyl acetate:methanol:water=8:1:0.5) to give a colorless amorphous product (7.5 mg, 28% yield, 98% enantiomeric excess value). The structure of the product was confirmed by 1H-NMR (CD3OD): δ 7.76 (d, 2H, J=8.6 Hz, Ar), 7.75 (d, 2H, J=8.6 Hz, Ar), 7.64 (t, 1H, J=7.4 Hz, Ar), 7.52 (t, 2H, J=7.4 Hz, Ar), 7.47 (d, 2H, J=8.0 Hz, Ar ), 3.83(m, 1H, Hα), 3.35(m, 1H, Hβ), 3.09(m, 1H, Hβ).

storage

Store at +4°C

References

[1] Molecules, 2013, vol. 18, # 7, p. 8393 - 8401
[2] Heterocycles, 2013, vol. 87, # 10, p. 2119 - 2126

L-4-BENZOYLPHENYLALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

L-4-BENZOYLPHENYLALANINE Suppliers

China 113 Germany 1 India 1 Japan 1 United Kingdom 3 United States 19 Global 138

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Shanghai HC Biotech Co., Ltd

Tel: 021-20227858
Fax: +86-21-20227857
Email: sale@hcbiotech.com.cn
Country: China
ProdList: 1095
Advantage: 55

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Suzhou haiyu Biochem Industrial Co., LTD

Tel: 512-68097639 18013585858
Fax: 0512-
Email: 744942877@qq.com
Country: China
ProdList: 915
Advantage: 62

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Nanjing Derno Pharmaceutical Technology Co., Ltd.

Tel: 025-86957866 13952093866
Fax: 025-68661287
Email: sales@dernopharm.com
Country: China
ProdList: 932
Advantage: 58

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8258
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
ProdList: 6716
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Taian Jiaye Biotechnology Co.Ltd

Tel: 13127280945
Email: 285424065@qq.com
Country: China
ProdList: 9976
Advantage: 55

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 10063
Advantage: 58

Beijing Minruida Technology Co., Ltd.

Tel: 010-82387566 18001021521;
Fax: 82387566-801
Email: sales@mreda.com.cn
Country: China
ProdList: 10083
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Kanghua (Shanghai) New Drug Development Co., Ltd.

Tel: 021-61263370 18901917034
Email: xingli@glbiochem.com
Country: China
ProdList: 5637
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Shanghai Jifeng Biotechnology Co., Ltd.

Tel: 021-61263377 15023907684
Fax: 021-61263399
Email: 15800684150@163.com
Country: China
ProdList: 8131
Advantage: 58

Zhengzhou Alfa Chemical Co.,Ltd

Tel: +8618530059196
Email: sale04@alfachem.cn
Country: China
ProdList: 11784
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

GL Biochem (Shanghai) Ltd.

Tel: +86-021-61263370 +86-18901917034
Country: CHINA
ProdList: 3904
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Wuhan Monad Medicine Tech Co.,LTD

Tel: 02768782018 18771942761
Email: sales01@whmonad.com
Country: CHINA
ProdList: 979
Advantage: 58

GL Biochem(Binhai) Ltd.

Tel: +86-021-61263370 +8615301650015
Email: wuqiuyan@glschina.com
Country: China
ProdList: 2975
Advantage: 58

Shanghai Lanle Bird Industrial Co., Ltd.

Tel: 15021845385
Email: 765325601@qq.com
Country: China
ProdList: 3609
Advantage: 58

Binhai gill polypeptide co. LTD

Tel: 021-61263389 13524856427
Fax: WeChat630417570
Email: Joetang@glschina.com
Country: China
ProdList: 10000
Advantage: 58

Shanghai Anhua Biotechnology Co., Ltd.

Tel: 021-61263375 18168859245
Country: China
ProdList: 5958
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Wuxi maimo topp biotechnology co., LTD

Tel: 13771048682 13771048682
Email: linda-fu@mimotopes.cn
Country: China
ProdList: 5796
Advantage: 58

Jiangsu Hongmin Pharmaceutical Co., Ltd.

Tel: 18221292452
Email: fannieliu@glschina.com
Country: China
ProdList: 6798
Advantage: 58

Jiangsu Jitai Peptide Technology Co., Ltd.

Tel: 0515-8085-5066 13770132022
Email: sales05@gtaipeptide.com
Country: China
ProdList: 2675
Advantage: 58

Shenzhen DBU TECH Co. Ltd.

Tel: 13528871800
Fax: QQ:2405094377
Email: dbutech@163.com
Country: China
ProdList: 504
Advantage: 58

Jiangsu Shengkang Meixiang Technology Co., Ltd.

Tel: 18217475093
Email: 1615396342@qq.com
Country: China
ProdList: 4309
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Less

View Lastest Price from L-4-BENZOYLPHENYLALANINE manufacturers

Career Henan Chemical Co

Product: L-4-BENZOYLPHENYLALANINE 104504-45-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-22

104504-45-2, L-4-BENZOYLPHENYLALANINERelated Search:

4-Methylphenyl-L-alanine L-PHE(4-COCH3) H-PHE-ALA-OH PHE-GLY-GLY H-4-NITRO-PHE-OET HCL L-4-Iodophenylalanine 4-Methoxy-L-phenylalanine L-4-Chlorophenylalanine L-4-Fluorophenylalanine L-4-TERT-BUTYL-PHE H-Phe-D-Phe-OMe.HCl L-4-Nitrophenylalanine methyl ester hydrochloride 4-AMINOTETRAHYDROPYRAN-4-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE L-4-Cyanophenylalanine 4-Amino-L-phenylalanine hydrochloride METHYL 4-BROMO-L-PHENYLALANINATE HYDROCHLORIDE H-Phe(4-Cl)-OMe.HCl 4-Amino-L-phenylalanine

(S)-2-aMino-3-(4-benzoylphenyl)propanoic acid

p-benzoyl-L-phenylanaline

(2S)-2-aMino-3-(4-benzoylphenyl)propanoic acid

H-4-Bz-Phe-Oh

H-Bpa-OH H-Phe(4-Bz)-OH

L-4-BENZOYLPHENYLALANINE 1G

H-Bpa-OH H-Phe(4-Bz)

4-Benzoyl-L-phenylalanine≥ 99% (HPLC, Chiral purity)

H-L-Phe(4-Bz)-OH

L-Bpa-OH

4-BENZOYL-L-PHENYLALANINE

P-BENZOYL-L-PHENYLALANINE

P-BZ-PHENYLALANINE

L-P-BENZOYLPHENYLALANINE

H-PHE(P-BZ)-OH

H-PHE(4-BZ)-OH

H-PHE(4-BZO)-OH

H-P-BZ-PHE-OH

L-4-BENZOYLPHENYLALANINE

H-BPA-OH

4-Benzoylphenylalanine

Al660-1

4-Benzoyl-L-phenylalanine，98%

L-Phenylalanine, 4-benzoyl-

(S)-2-Amino-3-(4-benzoylphenyl)propanoicaci

(S) 2-Amino-3- (4-benzoylphenyl) propionic acid

(R)-3-amino-3-(3-(p-tolyloxy)phenyl)propanoic acid

104504-45-2

Phenylalanine analogs and other aromatic alpha amino acids

Amino Acid Derivatives

Amino Acids

proteins

Chiral Compound

a-amino