4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE

Product Name: 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE
CAS No.: 62968-37-0
Chemical Name: 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE
Synonyms: 4-(2-Chloropyrimidin-4-yl);2-Chloro-4-morpholine pyrimidine;4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE;4-(2-CHLORO-PYRIMIDIN-4-YL)-MORPHOLINE;Morpholine, 4-(2-chloro-4-pyrimidinyl)-
CBNumber: CB3689411
Molecular Formula: C8H10ClN3O
Formula Weight: 199.64
MOL File: 62968-37-0.mol

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4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: White to off-white Solid

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C598203
Product name: 4-(2-Chloropyrimidin-4-yl)morpholine
Packaging: 500mg
Price: $220
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC140787
Product name: 4-(2-Chloropyrimidin-4-yl)morpholine
Packaging: 1g
Price: $250
Updated: 2021/12/16

Matrix Scientific

Product number: 083952
Product name: 4-(2-Chloropyrimidin-4-yl)morpholine
Purity: 97%
Packaging: 1g
Price: $341
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC140787
Product name: 4-(2-Chloropyrimidin-4-yl)morpholine
Packaging: 2g
Price: $425
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0128196
Product name: 2-CHLORO-4-MORPHOLINOPYRIMIDINE
Purity: 95.00%
Packaging: 5MG
Price: $504.04
Updated: 2021/12/16

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4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Chemical Properties,Usage,Production

Synthesis

110-91-8

3934-20-1

62968-37-0

General procedure: 2,4-Dichloropyrimidine (1.0 g, 6.7 mmol) was suspended in ethanol (20 ml) under inert atmosphere, cooled to 0°C and stirred. To this suspension triethylamine (1.4 ml, 10.1 mmol) and morpholine (0.59 ml, 6.7 mmol) were added sequentially. The reaction mixture was stirred at 0°C for 3 hours. After completion of the reaction, the mixture was concentrated in vacuum, diluted with 1 M NaOH solution (20 ml) and extracted with ethyl acetate (3 x 20 ml). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to give a colorless solid. The crude product was recrystallized by ethyl acetate/hexane to give 2-chloro-4-morpholino pyrimidine (1.21 g, 90% yield) as a colorless solid, which did not require further purification.LC-MS (ESP) analysis showed m/z 200 [M+H]+ and retention time (R/T) = 3.26 min.

References

[1] Patent: US2006/199804, 2006, A1. Location in patent: Page/Page column 27
[2] Tetrahedron, 2015, vol. 71, # 29, p. 4859 - 4867
[3] Organic Letters, 2018, vol. 20, # 2, p. 473 - 476
[4] Patent: WO2017/58503, 2017, A1. Location in patent: Page/Page column 419-421
[5] European Journal of Medicinal Chemistry, 1991, vol. 26, # 7, p. 729 - 733

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE Suppliers

China 40 India 1 The Netherlands 1 United Kingdom 3 United States 12 Global 57

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View Lastest Price from 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 4-(2-chloropyrimidin-4-yl)morpholine 62968-37-0
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-13

62968-37-0, 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINERelated Search:

Moroxydine Diphenhydramine triflumezopyrim Trichloropyrimidine 2-Amino-4-chloro-6-methoxypyrimidine Morpholine Nitroxinil 4-(4-CHLORO-2-PYRIMIDINYL)MORPHOLINE 2-Chloro-4-(morpholin-4-yl)thieno[3,2-d]pyrimidine 5-bromo-2-chloro-4-morpholinopyrimidine 2-chloro-6,7-dimethoxy-4-(4-morpholinyl)quinazoline 4-(2-chloropyrimidin-4-yl)-2,6-dimethylmorpholine 4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE 4-(2,6-DICHLOROPYRIMIDIN-4-YL)MORPHOLINE 4-(6-Amino-2-chloro-5-nitro-4-pyrimidinyl)morpholine

4-(2-Chloropyrimidin-4-yl)

4-(2-CHLORO-4-PYRIMIDINYL)MORPHOLINE

4-(2-CHLORO-PYRIMIDIN-4-YL)-MORPHOLINE

Morpholine, 4-(2-chloro-4-pyrimidinyl)-

2-Chloro-4-morpholine pyrimidine

62968-37-0

62968-37-1

C8H10ClN3O

Halides

Pyrazines, Pyrimidines & Pyridazines