(S)-1-BOC-2-METHYLPYRROLIDINE

Product Name: (S)-1-BOC-2-METHYLPYRROLIDINE
CAS No.: 137496-71-0
Chemical Name: (S)-1-BOC-2-METHYLPYRROLIDINE
Synonyms: Zinc04203908;(S)-N-Boc-2-methylpyrrolidine;(S)-1-BOC-2-METHYLPYRROLIDINE;(S)-tert-Butyl 2-Methylpyrrolidine-1-carboxylate;Tert-butyl (2s)-2-methylpyrrolidine-1-carboxylate;1,1-Dimethylethyl (2S)-2-methyl-1-pyrrolidinecarboxylate;(S)-2-Methyl-pyrrolidine-1-carboxylic acid tert-butyl ester;(S)-tert-Butyl 2-methylpyrrolidine-1-carboxylateStructural picture;1-Pyrrolidinecarboxylic acid, 2-Methyl-, 1,1-diMethylethyl ester, (2S)-
CBNumber: CB3702826
Molecular Formula: C10H19NO2
Formula Weight: 185.26
MOL File: 137496-71-0.mol

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(S)-1-BOC-2-METHYLPYRROLIDINE Property

Boiling point:: 234.0±9.0 °C(Predicted)
Density: 0.962 g/mL at 25 °C
refractive index: n20/D 1.444
Flash point:: 82 °C
storage temp.: 2-8°C
pka: -1.21±0.40(Predicted)
Appearance: Colorless to light yellow Liquid
optical activity: Consistent with structure

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Safety

Hazard Codes: T,N
Risk Statements: 25-37/38-41-50
Safety Statements: 26-39-45-61
RIDADR: UN 2810 6.1/PG 3
HazardClass: 8, 6.1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B810280
Product name: (S)-tert-Butyl2-Methylpyrrolidine-1-carboxylate
Packaging: 500mg
Price: $130
Updated: 2021/12/16

AK Scientific

Product number: 6588AA
Product name: (S)-tert-Butyl2-methylpyrrolidine-1-carboxylate
Packaging: 500mg
Price: $144
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB149784
Product name: (S)-1-Boc-2-methylpyrrolidine
Packaging: 2g
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB149784
Product name: (S)-1-Boc-2-methylpyrrolidine
Packaging: 5G
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB149784
Product name: (S)-1-Boc-2-methylpyrrolidine
Packaging: 250mg
Price: $40
Updated: 2021/12/16

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(S)-1-BOC-2-METHYLPYRROLIDINE Chemical Properties,Usage,Production

Synthesis

132482-10-1

137496-71-0

Tert-butyl 2R-methanesulfonyloxymethylpyrrolidine-1-carboxylate (1.6 g, 5.73 mmol) was used as a raw material, and lithium triethylborohydride (1 M solution in THF, 17 mL, 17 mmol) was slowly added to its solution in 10 mL of tetrahydrofuran at 0 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 16 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and water and washed sequentially with 0.1 N HCl and saturated saline. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated to give tert-butyl (S)-2-methylpyrrolidine-1-carboxylate as a colorless transparent oil (0.930 g, 88% yield). Its NMR hydrogen spectrum (400 MHz, CDCl3) data were as follows: δ 3.83 (m, 1H), 3.38 (m, 2H), 1.92 (m, 3H), 1.58 (m, 1H), 1.48 (s, 9H), 1.2 (d, J = 8 Hz, 3H).

References

[1] Patent: WO2006/19833, 2006, A1. Location in patent: Page/Page column 61
[2] Tetrahedron Letters, 1995, vol. 36, # 8, p. 1223 - 1226

(S)-1-BOC-2-METHYLPYRROLIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-1-BOC-2-METHYLPYRROLIDINE Suppliers

China 46 Switzerland 1 United Kingdom 2 United States 12 Global 61

Shanghai Boyle Chemical Co., Ltd.

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Shandong Ono Chemical Co., Ltd.

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View Lastest Price from (S)-1-BOC-2-METHYLPYRROLIDINE manufacturers

Career Henan Chemical Co

Product: (S)-1-BOC-2-METHYLPYRROLIDINE 137496-71-0
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customise
Release date: 2018-08-09

137496-71-0, (S)-1-BOC-2-METHYLPYRROLIDINERelated Search:

N-(TERT-BUTOXYCARBONYL)-D-PROLINAL (3S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid BOC-L-Prolinol BOC-D-PRO-OME (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate N-Boc-Nortropinone (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid (2s)-n-boc-5-methylpyrrolidine-2-carboxylic acid 2-Boc-aminomethylpyrrolidine (2s,5s)-n-boc-5-methylpyrrolidine-2-carboxylic acid (2s,4r)-n-boc-4-methylpyrrolidine-2-carboxylic acid (R)-1-BENZYL-3-N-BOC-AMINOMETHYL PYRROLIDINE (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE (2s,4s)-n-boc-4-methylpyrrolidine-2-carboxylic acid (S)-N-Cbz-3-N-Boc-aminomethyl-pyrrolidine (R)-1-Boc-2-methylpyrrolidine hydrochloride,(R)-N-Boc-2-methylpyrrolidine (2s,5r)-n-boc-5-methylpyrrolidine-2-carboxylic acid (S)-3-N-BOC-AMINOMETHYL PYRROLIDINE

(S)-N-Boc-2-methylpyrrolidine

(S)-2-Methyl-pyrrolidine-1-carboxylic acid tert-butyl ester

Zinc04203908

(S)-tert-Butyl 2-Methylpyrrolidine-1-carboxylate

(S)-1-BOC-2-METHYLPYRROLIDINE

1-Pyrrolidinecarboxylic acid, 2-Methyl-, 1,1-diMethylethyl ester, (2S)-

Tert-butyl (2s)-2-methylpyrrolidine-1-carboxylate

(S)-tert-Butyl 2-methylpyrrolidine-1-carboxylateStructural picture

1,1-Dimethylethyl (2S)-2-methyl-1-pyrrolidinecarboxylate

137496-71-0

Heterocyclic Compounds