BOC-D-PRO-OME

Product Name: BOC-D-PRO-OME
CAS No.: 73323-65-6
Chemical Name: BOC-D-PRO-OME
Synonyms: (2R)-pyrroL;BOC-D-PRO-OME;BOC-D-PYRD(2)-OME;idine-1,2-dicarboxyL;Boc-D-methyl proline;BOC-D-PRO-OME USP/EP/BP;Bok - D - Methyl proline;BOC-D-PROLINE METHYL ESTER;N-Boc-D-proline methyl este;N-BOC-D-PROLINE METHYL ESTER
CBNumber: CB4138390
Molecular Formula: C11H19NO4
Formula Weight: 229.27
MOL File: 73323-65-6.mol

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BOC-D-PRO-OME Property

Boiling point:: 288.6±33.0 °C(Predicted)
Density: 1.120±0.06 g/cm3(Predicted)
refractive index: 1.4510-1.4550
storage temp.: Sealed in dry,2-8°C
solubility: Soluble in DMSO.
pka: -3.35±0.40(Predicted)
form: Oil
color: Clear Colourless
optical activity: 59.8°(C=0.01g/ml MEOH)
InChI: InChI=1S/C11H19NO4/c1-11(2,3)16-10(14)12-7-5-6-8(12)9(13)15-4/h8H,5-7H2,1-4H3/t8-/m1/s1
InChIKey: WVDGSSCWFMSRHN-MRVPVSSYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC[C@@H]1C(OC)=O
CAS DataBase Reference: 73323-65-6(CAS DataBase Reference)

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Safety

HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

H371May cause damage to organs

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4787
Product name: N-(tert-Butoxycarbonyl)-D-proline Methyl Ester
Purity: >98.0%(GC)
Packaging: 1g
Price: $26
Updated: 2025/07/31

TCI Chemical

Product number: B4787
Product name: N-(tert-Butoxycarbonyl)-D-proline Methyl Ester
Purity: >98.0%(GC)
Packaging: 5g
Price: $76
Updated: 2025/07/31

TRC

Product number: B664205
Product name: N-Boc-D-prolineMethylEster
Packaging: 10g
Price: $225
Updated: 2021/12/16

Usbiological

Product number: 265160
Product name: Boc-D-proline methyl ester
Packaging: 500mg
Price: $333
Updated: 2021/12/16

Chem-Impex

Product number: 06651
Product name: Boc-D-proline methyl ester
Purity: ≥ 99% (HPLC)
Packaging: 5G
Price: $352
Updated: 2021/12/16

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BOC-D-PRO-OME Chemical Properties,Usage,Production

Uses

N-Boc-D-proline methyl ester is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

Synthesis

37784-17-1

74-88-4

73323-65-6

To a mixture of (R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid (5.8 g, 27 mmol) and potassium carbonate (8.6 g, 62 mmol) in tetrahydrofuran (160 mL) was added iodomethane (4.0 mL, 65 mmol). The reaction mixture was heated to reflux for 17 hours and subsequently cooled to room temperature. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by automated column chromatography using petroleum ether/ethyl acetate (3:1, v/v) as eluent to afford (R)-1-tert-butyl 2-methyl pyrrolidine-1,2-dicarboxylate (6.0 g, 65% yield) as a yellow oil.

References

[1] Patent: WO2013/131018, 2013, A1. Location in patent: Page/Page column 38

BOC-D-PRO-OME Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-D-PRO-OME Suppliers

Americas 1 China 158 Europe 2 Germany 2 India 5 Japan 3 Switzerland 1 United Kingdom 1 United States 20 Global 193

Shanghai Chiral Chemicals Inc.

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Fax: 86-021-51714507
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Shandong Lonyuta Pharmaceutical Technology Co., Ltd

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Email: Fu_qx@inyelchem.com
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Alfa Aesar

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Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
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Wuhan Chemwish Technology Co., Ltd

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Capot Chemical Co., Ltd

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Fax: 0086-571-85864795
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Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
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Accela ChemBio Co.,Ltd.

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Fax: 021-50795055
Email: sales@accelachem.com
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ProdList: 11035
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View Lastest Price from BOC-D-PRO-OME manufacturers

Career Henan Chemical Co

Product: BOC-D-PRO-OME 73323-65-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: KG/T
Release date: 2019-12-17

73323-65-6, BOC-D-PRO-OMERelated Search:

D-Proline N-Boc-D-proline 1-Boc-Pyrrolidine Boc-L-Pro-OMe (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate BOC-D-PRO-OME 1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER (2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER Boc-lle-Pro-OMe (R)-N-BOC-5-METHOXYCARBONYL-2-PYRROLIDINONE BOC-D-HYP-OTBU BOC-ALA-PRO-OME BOC-ILE-PRO-OME (2R,4S)-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER (2R,4R)-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER (R)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

BOC-D-PROLINE METHYL ESTER

BOC-D-PRO-OME

BOC-D-PYRD(2)-OME

R-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER

N-ALPHA-T-BUTOXYCARBONYL-D-PROLINE METHYL ESTER

N-ALPHA-T-BUTOXYCARBONYL-D-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER

N-tert-Butoxycarbonyl-D-Proline methyl ester

BOC-D-PROLINE METHYLESTER LIQUID

N-BOC-D-PROLINE METHYL ESTER

O1-tert-Butyl O2-methyl (2R)-pyrrolidine-1,2-dicarboxylate

1-O-tert-butyl 2-O-methyl (2R)-pyrrolidine-1,2-dicarboxylate

(R)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

1-tert-Butyl 2-methyl (2R)-pyrrolidine-1,2-dicarboxylate

N-Boc-D-proline methyl este

(R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate

(R)-1-tert-Butyl 2-Methyl pyrrolidine-1,2-dicarboxylate

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-diMethylethyl) 2-Methyl ester, (2R)-

Bok - D - Methyl proline

(R)-Boc-pyrrolidine-2-carboxylic acid methyl ester

Boc-D-proline methyl ester≥ 99% (HPLC)

N-(tert-Butoxycarbonyl)-D-proline Methyl Ester &gt

(2R)-pyrroL

idine-1,2-dicarboxyL

BOC-D-PRO-OME USP/EP/BP

1-(1,1-Dimethylethyl) 2-methyl (2R)-1,2-pyrrolidinedicarboxylate

1-(tert-butyl) 2-methyl (R)-pyrrolidine-1,2-dicarboxylate

Boc-D-methyl proline

N-Boc-D-proline methyl ester, 95%

O1-tert-Butyl O2-methyl (2R)-pyrrolidine-1,2-dicarboxylate - [B15682]

73323-65-6

Pyrrole&Pyrrolidine&Pyrroline