N-Boc-Trans-4-Hydroxy-D-proline methyl ester

Product Name: N-Boc-Trans-4-Hydroxy-D-proline methyl ester
CAS No.: 135042-17-0
Chemical Name: N-Boc-Trans-4-Hydroxy-D-proline methyl ester
Synonyms: Boc-trans-D-Hyp-OMe;Boc-D-trans-Hyp-OMe;trans-Boc-D-Hpy-Ome;N-Boc-trans-D-Hyp-Ome;(Tert-Butoxy)Carbonyl D-trans-Hyp-OMe;Methyl (4S)-1-Boc-4-hydroxy-D-prolinate;Boc-trans-4-Hydroxy-D-proline Methyl ester;N-Boc-Trans-4-Hydroxy-D-Proline Methyl Este;(2R,4S)-N-Boc-4-hydroxyproline methyl ester;N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
CBNumber: CB21561519
Molecular Formula: C11H19NO5
Formula Weight: 245.27
MOL File: 135042-17-0.mol

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N-Boc-Trans-4-Hydroxy-D-proline methyl ester Property

Boiling point:: 335.2±42.0 °C(Predicted)
Density: 1.216±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: 2-8°C
pka: 14.27±0.40(Predicted)
form: Solid
color: White to off-white
InChI: InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m0/s1
InChIKey: MZMNEDXVUJLQAF-JGVFFNPUSA-N
SMILES: N1(C(OC(C)(C)C)=O)C[C@@H](O)C[C@@H]1C(OC)=O
CAS DataBase Reference: 135042-17-0

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: R701033
Product name: (2R,4S)-1-tert-Butyl2-Methyl4-Hydroxypyrrolidine-1,2-dicarboxylate
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB142238
Product name: (2R,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB142238
Product name: (2R,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
Packaging: 2g
Price: $160
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-UM
Product name: 1-tert-Butyl 2-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
Purity: 97.0%
Packaging: 5G
Price: $188
Updated: 2021/12/16

ChemPep

Product number: 180835
Product name: Boc-trans-D-Hyp-OMe
Packaging: 5g
Price: $300
Updated: 2021/12/16

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N-Boc-Trans-4-Hydroxy-D-proline methyl ester Chemical Properties,Usage,Production

Uses

N-Boc-Trans-4-Hydroxy-D-proline methyl ester is a valuable organic compound that could be used to synthesis 1-tert-Butyl 2-methyl (2R)-4-oxopyrrolidine-1,2-dicarboxylate.

Application

N-Boc-Trans-4-Hydroxy-D-proline methyl ester is mainly used as a chiral building block in drug development and organic synthesis, especially as a non-cleaving linker in the synthesis of antibody-drug conjugates (ADCs), and plays a key role in proteomics research, peptide synthesis and the development of complex bioactive molecules.

IC 50

Non-cleavable Linker

N-Boc-Trans-4-Hydroxy-D-proline methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-Trans-4-Hydroxy-D-proline methyl ester Suppliers

China 155 India 5 United Kingdom 2 United States 12 Global 174

Nanjing Junnahe Biopharmaceutical Co., Ltd

Tel: 025-58367986 17351780683
Fax: QQ3209878052
Email: amy.xiang@ally-chem.com
Country: China
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Sichuan Tongsheng Amino acids Co.,Ltd.

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Jia Xing Isenchem Co.,Ltd

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Pure Chemistry Scientific Inc.

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Accela ChemBio Co.,Ltd.

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Shanghai Boc Chemical Co.,Ltd

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Nanjing Chemlin Chemical Co., Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
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China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
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View Lastest Price from N-Boc-Trans-4-Hydroxy-D-proline methyl ester manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER 135042-17-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Career Henan Chemical Co

Product: N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER 135042-17-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-05-25

135042-17-0, N-Boc-Trans-4-Hydroxy-D-proline methyl esterRelated Search:

N-BOC-TRANS-4-CYANO-L-PROLINE N-BOC-TRANS-4-CYANO-L-PROLINE METHYL ESTER (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate N-Boc-trans-4-Hydroxy-L-proline methyl ester N-Boc-cis-4-Hydroxy-L-proline methyl ester BOC-D-HYP-OTBU BOC-D-PRO-OME N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER METHYL-R-N-(METHOXY CARBONYL)-PROLINE ESTER trans-4-Hydroxy-D-proline TRANS-4-HYDROXY-L-PROLINE METHYL ESTER (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid (2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID (S)-Methyl-2-Boc-AMino-4-pentenoic acid (2R,4R)-1-[(tert-butoxy)carbonyl]-4-fluoropyrrolidine-2-carboxylic acid N-BOC-SERINOL, 97 N-Boc-trans-4-amino-L-proline methyl ester hydrochloride N-BOC-CYCLOHEXAMIDE

N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER

N-Boc-Trans-4-Hydroxy-D-Proline Methyl Este

Boc-trans-D-Hyp-OMe

(2R,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

(2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

(2R,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-Methyl ester (N-Boc-trans-4-Hydroxy-D-proline Methyl ester

1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2R,4S)-

Boc-trans-4-Hydroxy-D-proline Methyl ester

N-tert-butoxycarbonyl-trans-4-hydroxy-D-proline Methyl ester

(2R,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

1-tert-butyl 2-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

Methyl (4S)-1-Boc-4-hydroxy-D-prolinate

N-Boc-Trans-5-Hydroxy-D-Proline Methyl Ester

(2R,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl

Methyl (2R,4S)-1-Boc-4-hydroxypyrrolidine-2-carboxylate

(Tert-Butoxy)Carbonyl D-trans-Hyp-OMe

(2R,4S)-N-Boc-4-hydroxyproline methyl ester

Boc-D-trans-Hyp-OMe

(2R,4S)-N-Boc-trans-4-hydroxy-D-proline methyl ester

N-Boc-trans-D-Hyp-Ome

1-O-tert-butyl 2-O-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER (CAS NO.135042-17-0)

N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER USP/EP/BP

trans-Boc-D-Hpy-Ome

1-(1,1-Dimethylethyl) 2-methyl (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate

(2R,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate/N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER

1-(tert-Butyl) 2-methyl (2R,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate

135042-17-0